Pragmatic Randomized Trial of Proton vs. Photon Therapy for Patients With Non-Metastatic Breast Cancer: A Radiotherapy Comparative Effectiveness (RADCOMP) Consortium Trial
Public ClinicalTrials.gov record NCT02603341. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
A pragmatic randomized clinical trial of patients with locally advanced breast cancer randomized to either proton or photon therapy and followed longitudinally for cardiovascular morbidity and mortality, health-related quality of life, and cancer control outcomes. Quality of life is the outcome measure for the estimated primary completion date of December, 2024, www.radcomp.org.
Study identification
- NCT ID
- NCT02603341
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 1,238 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 21 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 6, 2016 (Actual)
- Primary completion
- Nov 2036 (Estimated)
- Completion
- Nov 2036 (Estimated)
- Last update posted
- Nov 6, 2025
2016 – 2036
United States locations
- U.S. sites
- 40
- U.S. states
- 22
- U.S. cities
- 36
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama | Birmingham | Alabama | 35233 | — |
| Mayo Clinic-Arizona | Phoenix | Arizona | 85054 | — |
| UC San Diego | San Diego | California | 92121 | — |
| Georgetown University Medical Center | Washington D.C. | District of Columbia | 20007 | — |
| University of Miami Sylvester Cancer Center at Coral Gables | Coral Gables | Florida | 33146 | — |
| University of Miami Sylvester Cancer Center - Deerfield | Deerfield Beach | Florida | 33442 | — |
| University of Florida Health | Gainesville | Florida | 32610 | — |
| University of Florida Health Proton Therapy Institute | Jacksonville | Florida | 32206 | — |
| University of Miami Sylvester Cancer Center | Miami | Florida | 33136 | — |
| Miami Cancer Insititute | Miami | Florida | 33176 | — |
| Orlando Health | Orlando | Florida | 32806 | — |
| Emory University | Atlanta | Georgia | 30322 | — |
| Northwestern Medicine Proton Center | Chicago | Illinois | 60190 | — |
| Willis Knighton | Shreveport | Louisiana | 71103 | — |
| University of Maryland | Baltimore | Maryland | 21201 | — |
| Johns Hopkins | Baltimore | Maryland | 21287 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Mass General/North Shore Cancer Center | Danvers | Massachusetts | 01923 | — |
| McLaren Proton Therapy | Flint | Michigan | 48532 | — |
| William Beaumont | Royal Oak | Michigan | 48073 | — |
| Mayo Clinic-Rochester | Rochester | Minnesota | 55905 | — |
| Washington University, St. Louis | St Louis | Missouri | 63110 | — |
| RWJ University Hospital Hamilton | Hamilton | New Jersey | 08690 | — |
| Cancer Institute of NJ | New Brunswick | New Jersey | 08903 | — |
| ProCure Proton Therapy Center | Somerset | New Jersey | 07728 | — |
| New York Proton Center | New York | New York | 10035 | — |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | — |
| University of Cincinnati | Cincinnati | Ohio | 45267 | — |
| University Hospitals, Case Medical Center | Cleveland | Ohio | 44106 | — |
| University Pointe, University of Cincinnati | West Chester | Ohio | 45069 | — |
| Oklahoma University - Stephenson Cancer Center | Oklahoma City | Oklahoma | 73104 | — |
| Pinnacle Health Cancer Institute | Harrisburg | Pennsylvania | 17109 | — |
| Abramson Cancer Center at Penn Medicine | Philadelphia | Pennsylvania | 19104 | — |
| Chester County Hospital | West Chester | Pennsylvania | 19380 | — |
| Thompson Proton Center | Knoxville | Tennessee | 37909 | — |
| MD Anderson Cancer Center | Houston | Texas | 77030 | — |
| Texas Center for Proton Therapy | Irving | Texas | 75063 | — |
| Inova Schar Cancer Institute | Fairfax | Virginia | 22031 | — |
| Seattle Cancer Care Alliance | Seattle | Washington | 98133 | — |
| University of Washington | Seattle | Washington | 98195 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02603341, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 6, 2025 · Synced Oct 25, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02603341 live on ClinicalTrials.gov.