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Completed Phase 2Phase 3 Interventional Results available

Selinexor in Advanced Liposarcoma

ClinicalTrials.gov ID: NCT02606461

Public ClinicalTrials.gov record NCT02606461. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 23, 2026, 6:52 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2-3, Multicenter, Randomized, Double-blind Study of Selinexor (KPT-330) Versus Placebo in Patients With Advanced Unresectable Dedifferentiated Liposarcoma (DDLS)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a randomized, multicenter, double-blind, placebo-controlled, Phase 2-3 study of patients diagnosed with advanced unresectable dedifferentiated liposarcoma. Approximately 342 total patients will be randomized to study treatment (selinexor or placebo).

Study identification

NCT ID
NCT02606461
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2, Phase 3
Lead sponsor
Karyopharm Therapeutics Inc
Industry
Enrollment
342 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
12 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 4, 2016 (Actual)
Primary completion
Oct 28, 2020 (Actual)
Completion
Oct 26, 2021 (Actual)
Last update posted
Jan 23, 2023

2016 – 2021

United States locations

U.S. sites
26
U.S. states
18
U.S. cities
21
Facility City State ZIP Site status
Cedars-Sinai Medical Center Los Angeles California 90048 —
University of California, Los Angeles Los Angeles California 90095 —
Sarcoma Oncology Center Santa Monica California 90403 —
Stanford University Stanford California 94305 —
University of Colorado-Denver Denver Colorado 80202 —
Yale Cancer Center New Haven Connecticut 06520-8032 —
Mayo Clinic Jacksonville Florida 32224 —
Northwestern Memorial Hospital Chicago Illinois 60611 —
Johns Hopkins Baltimore Maryland 21231 —
Massachusetts General Hospital Boston Massachusetts 02114 —
Dana Farber Cancer Institute Boston Massachusetts 02215 —
University of Michigan Ann Arbor Michigan 48109 —
Mayo Clinic Rochester Rochester Minnesota 55905 —
Washington University School of Medicine St Louis Missouri 63110 —
Columbia University Medical Center New York New York 10032 —
Memorial Sloan Kettering Cancer Center New York New York 10065 —
Northwell Health Physicians Partners New York New York 11042 —
Duke Institute of Cancer Durham North Carolina 27710 —
James Cancer Center, Ohio State University Columbus Ohio 43210-1240 —
Oregon Health and Science Portland Oregon 97239 —
University of Pennsylvania Philadelphia Pennsylvania 19106 —
Fox Chase Cancer Center Philadelphia Pennsylvania 19111 —
University of Pittsburgh Medical Center (UPMC) Pittsburgh Pennsylvania 15232 —
Vanderbilt Nashville Tennessee 37232 —
MD Anderson Houston Texas 77030 —
Fred Hutchinson Cancer Research Center Seattle Washington 98109 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 45 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02606461, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 23, 2023 · Synced Oct 23, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT02606461 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →