Safety and Efficacy of Inhaled Treprostinil in Adult PH With ILD Including CPFE
Public ClinicalTrials.gov record NCT02630316. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Randomized, Double-Blinded, Placebo-Controlled Trial to Evaluate the Safety and Efficacy of Inhaled Treprostinil in Subjects With Pulmonary Hypertension Due to Parenchymal Lung Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This was a multicenter, randomized (1:1 inhaled treprostinil: placebo), double-blinded, placebo-controlled trial to evaluate the safety and efficacy of inhaled treprostinil in subjects with pre-capillary pulmonary hypertension (PH) associated with interstitial lung disease (ILD) including combined pulmonary fibrosis and emphysema (CPFE). The study included 326 patients at approximately 120 clinical trial centers. The treatment phase of the study lasted approximately 16 weeks. Patients who completed all required assessments were eligible to enter an open-label, extension study (RIN-PH-202).
Study identification
- NCT ID
- NCT02630316
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Enrollment
- 326 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 3, 2017 (Actual)
- Primary completion
- Dec 26, 2019 (Actual)
- Completion
- Dec 26, 2019 (Actual)
- Last update posted
- Jul 27, 2022
2017 – 2019
United States locations
- U.S. sites
- 96
- U.S. states
- 34
- U.S. cities
- 74
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| IMC-Diagnostic & Medical Clinic | Mobile | Alabama | 36604 | — |
| Arizona Pulmonary Specialists, Ltd. | Phoenix | Arizona | 85012 | — |
| St. Joseph's Hospital and Medical Center | Phoenix | Arizona | 85013 | — |
| University of Arizona | Tucson | Arizona | 85724 | — |
| Cedars-Sinai Medical Center, Advanced Health Sciences Pavilion | Beverly Hills | California | 90211 | — |
| University of California San Francisco - Fresno | Fresno | California | 93701 | — |
| University of California San Diego | La Jolla | California | 92093 | — |
| VA Long Beach Healthcare System | Long Beach | California | 90822 | — |
| University of Southern California Health Sciences | Los Angeles | California | 90033 | — |
| Department of Veterans Affairs Greater Los Angeles Healthcare System | Los Angeles | California | 90073 | — |
| Pacific Pulmonary Medical Group | Riverside | California | 92505 | — |
| Kaiser Permanente - Roseville | Roseville | California | 95825 | — |
| University of California Davis Medical Center | Sacramento | California | 95817 | — |
| Kaiser Permanente | San Francisco | California | 94115 | — |
| University of Colorado Hospital - Cardiac and Vascular Center | Aurora | Colorado | 80045 | — |
| National Jewish Health | Denver | Colorado | 80206 | — |
| Yale New Haven Hospital | New Haven | Connecticut | 06510 | — |
| Medstar Georgetown University Hospital | Washington D.C. | District of Columbia | 20007 | — |
| MedStar Washington Hospital Center | Washington D.C. | District of Columbia | 20010 | — |
| Florida Lung, Asthma & Sleep Specialists, P.A. | Celebration | Florida | 34747 | — |
| St. Francis Sleep, Allergy and Lung Institute | Clearwater | Florida | 33765 | — |
| University of Florida Clinical Research Center | Gainesville | Florida | 32610 | — |
| University of Florida College of Medicine, Jacksonville | Jacksonville | Florida | 32209 | — |
| Mayo Clinic Jacksonville | Jacksonville | Florida | 32224 | — |
| St. Vincent's Health System | Jacksonville | Florida | 33204 | — |
| University of Miami | Miami | Florida | 33136 | — |
| Florida Hospital | Orlando | Florida | 32804 | — |
| South Miami Heart Specialists | South Miami | Florida | 33143 | — |
| Tampa General Hospital Center of Research Excellence | Tampa | Florida | 33606 | — |
| Cleveland Clinic Florida | Weston | Florida | 33331 | — |
| The Emory Clinic | Atlanta | Georgia | 30322 | — |
| Piedmont - Georgia Lung Associates | Austell | Georgia | 30106 | — |
| Wellstar Medical Group - Pulmonary Medicine | Marietta | Georgia | 30060 | — |
| Northwestern University School of Medicine | Chicago | Illinois | 60611 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| University of Illinois at Chicago Hospital | Chicago | Illinois | 60612 | — |
| University of Chicago Medical Center | Chicago | Illinois | 60637 | — |
| Loyola University Medical Center | Maywood | Illinois | 60153 | — |
| U Health Physicians Advanced Heart and Lung Clinic | Indianapolis | Indiana | 46202 | — |
| Community Heart and Vascular Hospital East | Indianapolis | Indiana | 46250 | — |
| St. Vincent Medical Group, Inc. | Indianapolis | Indiana | 46260 | — |
| University of Iowa Hospitals & Clinics | Iowa City | Iowa | 52242 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| University of Kentucky Medical Center | Lexington | Kentucky | 40536 | — |
| University of Louisville Clinical Trials Unit | Louisville | Kentucky | 40202 | — |
| Louisiana State University Health Sciences Center New Orleans | New Orleans | Louisiana | 70112 | — |
| Chest Medicine Associates | South Portland | Maine | 04106 | — |
| University of Maryland Medical Center | Baltimore | Maryland | 21201 | — |
| Johns Hopkins University Pulmonary and Critical Care Medicine | Baltimore | Maryland | 21205 | — |
| Tufts Medical Center | Boston | Massachusetts | 02111 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Brigham & Women's Hospital | Boston | Massachusetts | 02115 | — |
| Spectrum Health Heart and Lung Specialized Care Clinic | Grand Rapids | Michigan | 49503 | — |
| University of Minnesota | Minneapolis | Minnesota | 55455 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216 | — |
| Saint Luke's Hospital of Kansas City | Kansas City | Missouri | 64111 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| The University of New Mexico Clinical and Translational Science Center | Albuquerque | New Mexico | 87131 | — |
| Albany Medical College | Albany | New York | 12208 | — |
| New York Methodist Hospital | Brooklyn | New York | 11215 | — |
| Northwell Health | New Hyde Park | New York | 11040 | — |
| NYU Langone Medical Center | New York | New York | 10016 | — |
| Mount Sinai Medical Center | New York | New York | 10029 | — |
| New York Presbyterian - Weill Cornell Medical Center | New York | New York | 10065 | — |
| University of North Carolina at Chapel Hill | Chapel Hill | North Carolina | 27599 | — |
| Duke University Medical Center-Duke South Clinic | Durham | North Carolina | 27710 | — |
| Pinehurst Medical Clinic, Inc. | Pinehurst | North Carolina | 28374 | — |
| The Lindner Research Center at The Christ Hospital | Cincinnati | Ohio | 45219 | — |
| University of Cincinnati Health | Cincinnati | Ohio | 45267 | — |
| University Hospitals Cleveland Medical Center | Cleveland | Ohio | 44106 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| The Ohio State University Medical Center | Columbus | Ohio | 43221 | — |
| INTEGRIS Baptist Medical Center | Oklahoma City | Oklahoma | 73112 | — |
| Penn Medicine University City | Philadelphia | Pennsylvania | 19104 | — |
| Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212 | — |
| UPMC Montifiore University Hospital | Pittsburgh | Pennsylvania | 15213 | — |
| AnMed Health Medical Center | Anderson | South Carolina | 29621 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Statcare Pulmonary Consultants | Knoxville | Tennessee | 37919 | — |
| Baylor University Medical Center | Dallas | Texas | 75246 | — |
| UT Southwestern Medical Center | Dallas | Texas | 75390 | — |
| Texas Tech University Health Sciences Center | El Paso | Texas | 79905 | — |
| Houston Methodist | Houston | Texas | 77030 | — |
| Memoral Hermann Hospital - Texas Medical Center | Houston | Texas | 77030 | — |
| Michael E. DeBakey VA Medical Center | Houston | Texas | 77030 | — |
| The University of Texas Health Science Center at San Antonio | San Antonio | Texas | 78229 | — |
| Vermont Lung Center | Colchester | Vermont | 05446 | — |
| Inova Fairfax Medical Campus | Fairfax | Virginia | 22042 | — |
| Sentara Norfolk General Hospital | Norfolk | Virginia | 23507 | — |
| Pulmonary Associates of Richmond | Richmond | Virginia | 23229 | — |
| University of Washington Medical Center | Seattle | Washington | 98195 | — |
| University of Wisconsin School of Medicine and Public Health | Madison | Wisconsin | 53792 | — |
| Aurora St. Luke's Medical Center | Milwaukee | Wisconsin | 53215 | — |
| Medical College of Wisconsin/Froedtert Hospital | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02630316, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 27, 2022 · Synced Oct 27, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02630316 live on ClinicalTrials.gov.