PARTNER 3 Trial: Safety and Effectiveness of the SAPIEN 3 Transcatheter Heart Valve in Low Risk Patients With Aortic Stenosis
Public ClinicalTrials.gov record NCT02675114. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Prospective, Randomized, Controlled, Multi-Center Study to Establish the Safety and Effectiveness of the SAPIEN 3 Transcatheter Heart Valve in Low Risk Patients Who Have Severe, Calcific, Aortic Stenosis Requiring Aortic Valve Replacement
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
To establish the safety and effectiveness of the Edwards SAPIEN 3 Transcatheter Heart Valve (THV) in patients with severe, calcific aortic stenosis who are at low operative risk for standard aortic valve replacement.
Study identification
- NCT ID
- NCT02675114
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 1,000 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- Not listed
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 2016 (Actual)
- Primary completion
- Nov 16, 2020 (Actual)
- Completion
- Dec 2029 (Estimated)
- Last update posted
- Jan 14, 2026
2016 – 2029
United States locations
- U.S. sites
- 68
- U.S. states
- 32
- U.S. cities
- 62
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama | Birmingham | Alabama | 35294 | — |
| Banner University Medical Center | Phoenix | Arizona | 85006 | — |
| Mills/Peninsula Health Services | Burlingame | California | 94010 | — |
| Cedars-Sinai Medical Center | Los Angeles | California | 90048 | — |
| University of California, Los Angeles/Ronald Reagan Medical Center | Los Angeles | California | 90095 | — |
| Hoag Hospital | Newport Beach | California | 92663 | — |
| Stanford Hospital and Clinics | Palo Alto | California | 94305 | — |
| Sutter Health Sacramento | Sacramento | California | 95816 | — |
| Kaiser Permanente San Francisco | San Francisco | California | 94115 | — |
| UC Health Northern Colorado/Medical Center of the Rockies | Loveland | Colorado | 80538 | — |
| Hartford | Hartford | Connecticut | 06102 | — |
| JFK Medical Center / Atlantic Clinical Research Collaborative | Atlantis | Florida | 33462 | — |
| University of Florida, Gainesville | Gainesville | Florida | 32610 | — |
| Mount Sinai Medical Center | Miami Beach | Florida | 33140 | — |
| Florida Hospital | Orlando | Florida | 32803 | — |
| Emory University | Atlanta | Georgia | 30322 | — |
| The Queen's Medical Center | Honolulu | Hawaii | 96813 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| NorthShore University HealthSystem Research Institute | Evanston | Illinois | 60201 | — |
| Prairie Education and Research Cooperative | Springfield | Illinois | 62701 | — |
| University of Iowa Hospitals and Clinics | Iowa City | Iowa | 52242 | — |
| Cardiovascular Research Institute of Kansas | Wichita | Kansas | 67226 | — |
| UPR - Louisiana State University Health Science Center | New Orleans | Louisiana | 70112 | — |
| Ochsner Clinic Foundation | New Orleans | Louisiana | 70121 | — |
| Central Maine Medical Center | Auburn | Maine | 04210 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| William Beaumont Hospital | Royal Oak | Michigan | 48073 | — |
| University of Minnesota Medical Center | Minneapolis | Minnesota | 55455 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Saint Luke's Hospital of Kansas City Mid America | Kansas City | Missouri | 64111 | — |
| Barnes-Jewish Hospital / Washington University | St Louis | Missouri | 63110 | — |
| Nebraska Heart Institute | Lincoln | Nebraska | 68526 | — |
| Dartmouth-Hitchcock Medical Center | Lebanon | New Hampshire | 03756 | — |
| Morristown Medical Center / Atlantic Health System Hospital | Morristown | New Jersey | 07962 | — |
| Newark Beth Israel | Newark | New Jersey | 07112 | — |
| Albany | Albany | New York | 12208 | — |
| University of Buffalo | Buffalo | New York | 14203 | — |
| Winthrop-University Hospital | Mineola | New York | 11501 | — |
| NYU Medical Center | New York | New York | 10016 | — |
| Cornell University | New York | New York | 10021 | — |
| Columbia University Medical Center/ New York Presbyterian Hospital | New York | New York | 10032 | — |
| Carolina's Health System | Charlotte | North Carolina | 28203 | — |
| UPR - Novant Health Heart and Vascular Institution | Charlotte | North Carolina | 28204 | — |
| Rex Hospital / NC Heart and Vascular Research | Raleigh | North Carolina | 27607 | — |
| The Christ Hospital, Cincinnati | Cincinnati | Ohio | 45219 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| Mount Carmel Health System | Columbus | Ohio | 43213 | — |
| Oklahoma Cardiovascular Research Group | Oklahoma City | Oklahoma | 73120 | — |
| UPR-Oklahoma Heart Institute | Tulsa | Oklahoma | 74104 | — |
| Providence Heart & Vascular Institute | Portland | Oregon | 97225 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212 | — |
| Lankenau Medical Center | Wynnewood | Pennsylvania | 19096 | — |
| York Hospital | York | Pennsylvania | 17403 | — |
| Baptist Memorial Hospital | Memphis | Tennessee | 38120 | — |
| Saint Thomas Health Services | Nashville | Tennessee | 37205 | — |
| Austin Heart | Austin | Texas | 78756 | — |
| Medical City Dallas Hospital | Dallas | Texas | 75230 | — |
| The University of Texas Health Science Center at Houston | Houston | Texas | 77030 | — |
| The Heart Hosptial Baylor Plano | Plano | Texas | 75093 | — |
| Intermountain Medical Center | Salt Lake City | Utah | 84157 | — |
| University of Virginia | Charlottesville | Virginia | 22904 | — |
| Fairfax INOVA | Falls Church | Virginia | 22042 | — |
| Sentara Cardiovascular Research Institute | Norfolk | Virginia | 23507 | — |
| University of Washington | Seattle | Washington | 98195 | — |
| University of Wisconsin | Madison | Wisconsin | 53792 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 9 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02675114, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 14, 2026 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02675114 live on ClinicalTrials.gov.