ClinicalTrials.gov record
Active, not recruiting Phase 2 Interventional

ExIST Study of LY2157299 (Galunisertib) in Rectal Cancer

ClinicalTrials.gov ID: NCT02688712

Public ClinicalTrials.gov record NCT02688712. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 4, 2026, 11:41 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase II Study of TGFβ Type I Receptor Inhibitor LY2157299 With Neoadjuvant Chemoradiation in Patients With Locally Advanced Rectal Adenocarcinoma

Study identification

NCT ID
NCT02688712
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 2
Lead sponsor
Providence Health & Services
Other
Enrollment
50 participants

Conditions and interventions

Interventions

  • Capecitabine Drug
  • Fluorouracil Drug
  • LY2157299 Drug
  • Tumor specific mesorectal excision Procedure

Drug · Procedure

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 23, 2016
Primary completion
Jan 25, 2026
Completion
Nov 30, 2026
Last update posted
Apr 12, 2026

2016 – 2026

United States locations

U.S. sites
1
U.S. states
1
U.S. cities
1
Facility City State ZIP Site status
Providence Cancer Center Portland Oregon 97213

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02688712, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 12, 2026 · Synced May 4, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02688712 live on ClinicalTrials.gov.

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