Aspirin Dosing: A Patient-Centric Trial Assessing Benefits and Long-term
Public ClinicalTrials.gov record NCT02697916. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Aspirin Dosing: A Patient-Centric Trial Assessing Benefits and Long-term Effectiveness
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
ADAPTABLE is a pragmatic clinical trial in which 15,000 patients who are at high risk for ischemic events will be randomly assigned in a 1:1 ratio to receive an aspirin dose of 81 mg/day vs. 325 mg/day. Study participants will be enrolled over 38 months. Maximum follow-up will be 50 months. The purpose of the study is to identify the optimal dose of aspirin for secondary prevention in patients with Atherosclerotic cardiovascular disease (ASCVD). The primary endpoint is a composite of all-cause death, hospitalization for MI, or hospitalization for stroke. The primary safety endpoint is hospitalization for major bleeding with an associated blood product transfusion.
Study identification
- NCT ID
- NCT02697916
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 15,076 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 2016 (Actual)
- Primary completion
- Jun 30, 2020 (Actual)
- Completion
- Jun 30, 2020 (Actual)
- Last update posted
- Jul 1, 2021
2016 – 2020
United States locations
- U.S. sites
- 40
- U.S. states
- 21
- U.S. cities
- 31
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| UCLA Medical Center | Los Angeles | California | 90095 | — |
| HealthCore | Wilmington | Delaware | 19801 | — |
| University of Florida Cardiology - Springhill | Gainesville | Florida | 32606 | — |
| Florida Hospital | Orlando | Florida | 32806 | — |
| Orlando Health | Orlando | Florida | 32806 | — |
| Bond Community Health Center | Tallahassee | Florida | 32301 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| University of Chicago Medical Center | Chicago | Illinois | 60637 | — |
| Indiana University | Indianapolis | Indiana | 46202 | — |
| University of Iowa Hospitals & Clinics | Iowa City | Iowa | 52242 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| Ochsner Health System | New Orleans | Louisiana | 70112 | — |
| Tulane University Heart & Vascular Institute | New Orleans | Louisiana | 70112 | — |
| Johns Hopkins Medical Center | Baltimore | Maryland | 21287 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| Essentia Health St. Mary's Medical Center | Duluth | Minnesota | 55805 | — |
| Allina Health | Minneapolis | Minnesota | 55407 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| University of Missouri | Columbia | Missouri | 65211 | — |
| University of Nebraska Medical Center | Omaha | Nebraska | 68196 | — |
| New York University School of Medicine | New York | New York | 10016 | — |
| Icahn School of Medicine at Mount Sinai | New York | New York | 10029 | — |
| Weill Cornell Medicine of Cornell University | New York | New York | 10065 | — |
| Montefiore Medical Center | New York | New York | 10461 | — |
| UNC Chapel Hill | Chapel Hill | North Carolina | 27514 | — |
| Duke University | Durham | North Carolina | 27701 | — |
| Wake Forest University Health Sciences | Winston-Salem | North Carolina | 27157 | — |
| Ohio State Univerity | Columbus | Ohio | 43210 | — |
| Penn State Milton S Hershey Medical Center | Hershey | Pennsylvania | 17033 | — |
| Temple University Hospital | Philadelphia | Pennsylvania | 19140 | — |
| University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | 15213 | — |
| Vanderbilt University | Nashville | Tennessee | 37203 | — |
| Baylor Scott and White Heart and Vascular Hospital | Dallas | Texas | 75226 | — |
| University of Texas-Southwestern | Dallas | Texas | 75390 | — |
| University of Texas Health Sciences Center at San Antonio | San Antonio | Texas | 78229 | — |
| Intermountain Medical Center | Salt Lake City | Utah | 84107 | — |
| University of Utah Hospitals and Clinics | Salt Lake City | Utah | 84112 | — |
| Marshfield Clinic | Marshfield | Wisconsin | 54449 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02697916, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 1, 2021 · Synced Oct 19, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02697916 live on ClinicalTrials.gov.