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Terminated Phase 2 Interventional Results available

A Study of INCB050465 in Combination With Ruxolitinib in Subjects With Myelofibrosis

ClinicalTrials.gov ID: NCT02718300

Public ClinicalTrials.gov record NCT02718300. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 23, 2026, 6:18 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2 Study of the Safety, Tolerability, and Efficacy of INCB050465 in Combination With Ruxolitinib in Subjects With Myelofibrosis

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to evaluate the safety, tolerability, and efficacy of the combination of parsaclisib and ruxolitinib in subjects with myelofibrosis.

Study identification

NCT ID
NCT02718300
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
Incyte Corporation
Industry
Enrollment
74 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 8, 2017 (Actual)
Primary completion
Jan 28, 2021 (Actual)
Completion
Apr 29, 2022 (Actual)
Last update posted
May 1, 2024

2017 – 2022

United States locations

U.S. sites
39
U.S. states
23
U.S. cities
36
Facility City State ZIP Site status
Birmingham Hematology & Oncolgy Associates Llc Birmingham Alabama 35223 —
Mayo Clinic Arizona Scottsdale Arizona 85259 —
Alta Bates Medical Center Berkeley California 94704 —
City of Hope National Medical Center Duarte California 91010 —
California Cancer Associates For Research and Excellence Fresno California 93720 —
University of Southern California Los Angeles California 90033 —
UCLA School of Medicine Los Angeles California 90095 —
Pcr Oncology Pismo Beach California 93449 —
California Cancer Assoc. for Research and Excellence San Marcos California 92069 —
Georgetown University Hospital Washington D.C. District of Columbia 20007 —
Shands Hospital Gainesville Florida 32610 —
Emory University Atlanta Georgia 30322 —
University of Chicago Medical Center Chicago Illinois 60637 —
Indiana Blood and Marrow Transplantation Indianapolis Indiana 46237 —
McFarland Clinic Ames Iowa 50010 —
University of Kansas Cancer Center Westwood Kansas 66205 —
Norton Cancer Institute Louisville Kentucky 40202 —
Saint Agnes Hospital Baltimore Maryland 21229 —
Cancer Center For Blood Disorders Bethesda Maryland 20817 —
Massachusetts General Hospital Boston Massachusetts 02114 —
Washington University School of Medicine St Louis Missouri 63130 —
Summit Medical Group Florham Park New Jersey 07932 —
Hackensack University Medical Center Hackensack New Jersey 07601 —
New Mexico Cancer Care Alliance Albuquerque New Mexico 87106 —
Roswell Park Cancer Institute Buffalo New York 14263 —
Mount Sinai School of Medicine New York New York 10029 —
Columbia University Medical Center New York New York 10032 —
Memorial Sloan Kettering Cancer Center New York New York 10065 —
Montefiore Medical Center The Bronx New York 10467 —
Oncology Hematology Care, Inc. Cincinnati Ohio 45230 —
Cleveland Clinic Cleveland Ohio 44195 —
Oregon Health & Science University Portland Oregon 97239 —
Rush University Medical Center Nashville Tennessee 37203 —
Baylor Scott and White Research Institute Dallas Texas 75246 —
Md Anderson Cancer Center Houston Texas 77030 —
Cancer Care Centers of South Texas San Antonio Texas 78217 —
Renovatio Clinical Consultants Llc The Woodlands Texas 77380 —
Va Salt Lake City Health Care System Salt Lake City Utah 84112 —
Vista Oncology Inc Ps Olympia Washington 98506 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02718300, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 1, 2024 · Synced Oct 23, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT02718300 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →