Injectable Cabotegravir Compared to TDF/FTC For PrEP in HIV-Uninfected Men and Transgender Women Who Have Sex With Men
Public ClinicalTrials.gov record NCT02720094. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2b/3 Double Blind Safety and Efficacy Study of Injectable Cabotegravir Compared to Daily Oral Tenofovir Disoproxil Fumarate/Emtricitabine For Pre-Exposure Prophylaxis in HIV-Uninfected Men and Transgender Women Who Have Sex With Men
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will evaluate the safety and efficacy of the injectable drug cabotegravir (CAB LA), for pre-exposure prophylaxis (PrEP) in HIV-uninfected cisgender men and transgender women who have sex with men (MSM and TGW).
Study identification
- NCT ID
- NCT02720094
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Enrollment
- 4,570 participants
Conditions and interventions
Conditions
Interventions
- Cabotegravir Oral Tablet Drug
- TDF/FTC tablets Drug
- Placebo for TDF/FTC tablets Drug
- Placebo for cabotegravir oral tablet Drug
- CAB LA Drug
- Placebo for CAB LA Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 19, 2016 (Actual)
- Primary completion
- May 14, 2020 (Actual)
- Completion
- Mar 31, 2025 (Actual)
- Last update posted
- Mar 19, 2026
2016 – 2025
United States locations
- U.S. sites
- 27
- U.S. states
- 17
- U.S. cities
- 23
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Alabama CRS | Birmingham | Alabama | 35294 | — |
| UCLA Vine Street Clinic CRS | Los Angeles | California | 90024 | — |
| UCLA CARE Center CRS | Los Angeles | California | 90035 | — |
| East Bay AIDS Center (EBAC) CRS | Oakland | California | 94609 | — |
| Bridge HIV CRS | San Francisco | California | 94143 | — |
| Children's Hospital Colorado CRS | Aurora | Colorado | 80045 | — |
| George Washington Univ. CRS | Washington D.C. | District of Columbia | 20037-1894 | — |
| The Ponce de Leon Center CRS | Atlanta | Georgia | 30308-2012 | — |
| The Hope Clinic of the Emory Vaccine Center CRS | Decatur | Georgia | 30030 | — |
| Adolescent & Young Adult Research at The CORE Center (AYAR at CORE) | Chicago | Illinois | 60612 | — |
| UIC Project WISH CRS | Chicago | Illinois | 60612 | — |
| New Orleans Adolescent Trials Unit CRS | New Orleans | Louisiana | 70112 | — |
| Johns Hopkins University CRS | Baltimore | Maryland | 21205 | — |
| Fenway Health (FH) CRS | Boston | Massachusetts | 02215-4302 | — |
| Washington University Therapeutics (WT) CRS | St Louis | Missouri | 63110-1010 | — |
| New Jersey Medical School Clinical Research Center CRS | Newark | New Jersey | 07103 | — |
| Weill Cornell Chelsea CRS | New York | New York | 10010 | — |
| Harlem Prevention Center CRS | New York | New York | 10027 | — |
| New York Blood Center CRS | New York | New York | 10065 | — |
| Bronx Prevention Research Center CRS | The Bronx | New York | 10451 | — |
| Chapel Hill CRS | Chapel Hill | North Carolina | 27599 | — |
| Greensboro CRS | Greensboro | North Carolina | 27401 | — |
| Cincinnati Clinical Research Site | Cincinnati | Ohio | 45219 | — |
| Ohio State University CRS | Columbus | Ohio | 43210 | — |
| Penn Prevention CRS | Philadelphia | Pennsylvania | 19104 | — |
| St. Jude Children's Research Hospital CRS | Memphis | Tennessee | 38105-3678 | — |
| Houston AIDS Research Team CRS | Houston | Texas | 77030 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 16 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02720094, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 19, 2026 · Synced Oct 23, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02720094 live on ClinicalTrials.gov.