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Completed Phase 1Phase 2 Interventional Results available

A Study of Itacitinib (INCB039110) in Combination With Ibrutinib in Subjects With Relapsed or Refractory Diffuse Large B-Cell Lymphoma

ClinicalTrials.gov ID: NCT02760485

Public ClinicalTrials.gov record NCT02760485. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Nov 8, 2026, 12:32 AM EST

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Official title

An Open-Label Phase 1/2 Study of Itacitinib (INCB039110) in Combination With Ibrutinib in Subjects With Relapsed or Refractory Diffuse Large B-Cell Lymphoma

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to evaluate the safety/tolerability and efficacy of itacitinib in combination with ibrutinib in subjects with relapsed or refractory diffuse large B-cell lymphoma (DLBCL)

Study identification

NCT ID
NCT02760485
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1, Phase 2
Lead sponsor
Incyte Corporation
Industry
Enrollment
33 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 29, 2016 (Actual)
Primary completion
Jun 6, 2022 (Actual)
Completion
Jun 6, 2022 (Actual)
Last update posted
Jun 15, 2023

2016 – 2022

United States locations

U.S. sites
21
U.S. states
15
U.S. cities
21
Facility City State ZIP Site status
Mayo Clinic Arizona Scottsdale Arizona 85259 —
City of Hope National Medical Center Duarte California 91010 —
Pacific Shores Medical Group Long Beach California 90813 —
LAC-USC Medical Center/Kenneth Norris Jr Cancer Hospital Los Angeles California 90033 —
Moores UC San Diego Cancer Center San Diego California 92093 —
Mount Sinai Comprehensive Cancer Center Miami Beach Florida 33140 —
Georgia Regents Research Institute Augusta Georgia 30912 —
University of Maryland Cancer Center Baltimore Maryland 21201 —
University of Michigan Cancer Center Ann Arbor Michigan 48109 —
Michigan State University Breslin Cancer Center Lansing Michigan 48910 —
St Vincent Frontier Cancer Center Billings Montana 59102 —
Comprehensive Cancer Center of Nevada Las Vegas Nevada 89169 —
Regional Cancer Center Associates, LLC Little Silver New Jersey 07739 —
Roswell Cancer Center Buffalo New York 14263 —
Memorial Sloan Kettering Cancer Center New York New York 10065 —
Toledo Clinic Cancer Centers Toledo Ohio 43623 —
Tulsa Cancer Center Tulsa Oklahoma 74146 —
Geisinger Medical Center Danville Pennsylvania 17822 —
University of Pennsylvania Health System Philadelphia Pennsylvania 19104 —
Houston Methodist Cancer Center Houston Texas 77030 —
Northwest Medical Specialists & Research Institute Puyallup Washington 98373 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02760485, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 15, 2023 · Synced Nov 8, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT02760485 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →