Study to Compare the Efficacy and Safety of Enzyme Replacement Therapies Avalglucosidase Alfa and Alglucosidase Alfa Administered Every Other Week in Patients With Late-onset Pompe Disease Who Have Not Been Previously Treated for Pompe Disease
Public ClinicalTrials.gov record NCT02782741. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3 Randomized, Multicenter, Multinational, Double-blinded Study Comparing the Efficacy and Safety of Repeated Biweekly Infusions of Avalglucosidase Alfa (neoGAA, GZ402666) and Alglucosidase Alfa in Treatment naïve Patients With Late-onset Pompe Disease
Study identification
- NCT ID
- NCT02782741
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Genzyme, a Sanofi Company
- Industry
- Enrollment
- 101 participants
Conditions and interventions
Interventions
- Alglucosidase alfa (GZ419829) Drug
- Avalglucosidase alfa (GZ402666) Drug
Drug
Eligibility (public fields only)
- Age range
- 3 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 1, 2016
- Primary completion
- Mar 18, 2020
- Completion
- May 30, 2023
- Last update posted
- Apr 3, 2024
2016 – 2023
United States locations
- U.S. sites
- 21
- U.S. states
- 18
- U.S. cities
- 21
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Investigational Site Number 8400015 | Phoenix | Arizona | 85013 | — |
| Investigational Site Number 8400020 | Los Angeles | California | 90095 | — |
| Investigational Site Number 8400011 | Orange | California | 92868 | — |
| Investigational Site Number 8400017 | Stanford | California | 94305 | — |
| Investigational Site Number 8400016 | Gainesville | Florida | 32610 | — |
| Investigational Site Number 8400007 | Decatur | Georgia | 30033 | — |
| Investigational Site Number 8400023 | Chicago | Illinois | 60611 | — |
| Investigational Site Number 8400002 | Iowa City | Iowa | 52242 | — |
| Investigational Site Number 8400012 | Kansas City | Kansas | 66160-7321 | — |
| Investigational Site Number 8400010 | Boston | Massachusetts | 02114 | — |
| Investigational Site Number 8400001 | Detroit | Michigan | 48201 | — |
| Investigational Site Number 8400019 | Minneapolis | Minnesota | 55455 | — |
| Investigational Site Number 8400026 | Great Neck | New York | 11020 | — |
| Investigational Site Number 8400008 | Valhalla | New York | 10595 | — |
| Investigational Site Number 8400006 | Durham | North Carolina | 27710 | — |
| Investigational Site Number 8400009 | Cincinnati | Ohio | 45267-0542 | — |
| Investigational Site Number 8400014 | Portland | Oregon | 97239 | — |
| Investigational Site Number 8400025 | Pittsburgh | Pennsylvania | 15213 | — |
| Investigational Site Number 8400018 | Salt Lake City | Utah | 84132 | — |
| Investigational Site Number 8400005 | Fairfax | Virginia | 22030 | — |
| Investigational Site Number 8400024 | Morgantown | West Virginia | 26506 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 48 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02782741, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 3, 2024 · Synced May 20, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02782741 live on ClinicalTrials.gov.