Long-term Safety of Tafamidis in Subjects With Transthyretin Cardiomyopathy
Public ClinicalTrials.gov record NCT02791230. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A PHASE 3 MULTICENTER, OPEN-LABEL STUDY TO EVALUATE THE SAFETY OF DAILY ORAL DOSING OF TAFAMIDIS MEGLUMINE (PF-06291826-83) 20 MG OR 80 MG [OR TAFAMIDIS (PF-06291826-00) 61 MG] IN SUBJECTS DIAGNOSED WITH TRANSTHYRETIN CARDIOMYOPATHY (ATTR-CM)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Open label study to evaluate tafamidis for the treatment of transthyretin cardiomyopathy
Study identification
- NCT ID
- NCT02791230
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,733 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 13, 2016 (Actual)
- Primary completion
- Oct 26, 2023 (Actual)
- Completion
- Nov 2, 2023 (Actual)
- Last update posted
- Feb 3, 2025
2016 – 2023
United States locations
- U.S. sites
- 41
- U.S. states
- 16
- U.S. cities
- 23
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| The Kirklin Clinic of UAB Hospital | Birmingham | Alabama | 35233 | — |
| Cardiovascular Clinical Trials Unit (CCTU) | Birmingham | Alabama | 35294 | — |
| University Hospital, University of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| California Heart Center | Beverly Hills | California | 90211 | — |
| Cedars-Sinai Medical Care Foundation | Beverly Hills | California | 90211 | — |
| Altman Clinical Translational Research Institute | La Jolla | California | 92037 | — |
| University of California, San Diego | La Jolla | California | 92037 | — |
| Cedars-Sinai Medical Center | Los Angeles | California | 90048 | — |
| University of California, San Diego Medical Center - Hillcrest | San Diego | California | 92103 | — |
| Center Adv Lab Medicine | San Diego | California | 92121 | — |
| UCSF Ambulatory Care Center | San Francisco | California | 94143 | — |
| University of California | San Francisco | California | 94143 | — |
| UCSF Cardiovascular Care and Prevention Center | San Francisco | California | 94158 | — |
| Stanford University Hospital and Clinics | Stanford | California | 94305 | — |
| Sylvester at Deerfield Beach | Deerfield Beach | Florida | 33136 | — |
| University of Miami Hospital & Clinics/Sylvester Comprehensive Cancer Center | Miami | Florida | 33136 | — |
| Northwestern Medical Group | Chicago | Illinois | 60611 | — |
| Northwestern Memorial Hospital | Chicago | Illinois | 60611 | — |
| Advocate Christ Medical Center | Oak Lawn | Illinois | 60453 | — |
| University of Maryland, Baltimore | Baltimore | Maryland | 21201 | — |
| Johns Hopkins University | Baltimore | Maryland | 21287 | — |
| Boston Medical Center Investigational Pharmacy | Boston | Massachusetts | 02118 | — |
| Boston Medical Center | Boston | Massachusetts | 02118 | — |
| Boston University Medical Center | Boston | Massachusetts | 02118 | — |
| Michigan Medicine,University of Michigan | Ann Arbor | Michigan | 48109 | — |
| Mayo Clinic Hospital-Rochester | Rochester | Minnesota | 55902 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Newark Beth Israel Medical Center | Newark | New Jersey | 07112 | — |
| NYU Langone Health | New York | New York | 10016 | — |
| Center for Advanced Cardiac Care | New York | New York | 10032 | — |
| Columbia University Irving Medical Center | New York | New York | 10032 | — |
| Duke University | Durham | North Carolina | 27710 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| OHSU Center for Health and Healing | Portland | Oregon | 97239 | — |
| OHSU Research Pharmacy Services | Portland | Oregon | 97239 | — |
| Oregon Health & Science University | Portland | Oregon | 97239 | — |
| Penn Presbyterian Medical Center | Philadelphia | Pennsylvania | 19104 | — |
| Vanderbilt Univ. Med. Ctr | Nashville | Tennessee | 37232 | — |
| Huntsman Cancer Hospital | Salt Lake City | Utah | 84112 | — |
| University of Utah Hospitals & Clinics | Salt Lake City | Utah | 84132 | — |
| University of Utah, Division of Cardiovascular Medicine | Salt Lake City | Utah | 84132 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 39 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02791230, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 3, 2025 · Synced Oct 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02791230 live on ClinicalTrials.gov.