Unrelated Donor Transplant Versus Immune Therapy in Pediatric Severe Aplastic Anemia
Public ClinicalTrials.gov record NCT02845596. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine the feasibility of comparing outcomes of patients treated de novo with immunosuppressive therapy (IST) versus matched unrelated donor (MUD) hematopoietic stem cell transplant (HSCT) for pediatric acquired severe aplastic anemia.
Study identification
- NCT ID
- NCT02845596
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 40 participants
Conditions and interventions
Conditions
Interventions
- cyclosporine Drug
- Matched Unrelated Donor Hematopoietic Stem Cell Transplant Procedure
- horse anti-thymocyte globulin (ATG) Drug
- rabbit anti-thymocyte globulin (ATG) Drug
- methotrexate Drug
- fludarabine Drug
- cyclophosphamide Drug
- low-dose total body irradiation (TBI) Radiation
- Immunosuppressive Therapy (IST) Procedure
Drug · Procedure · Radiation
Eligibility (public fields only)
- Age range
- Up to 25 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 2016 (Type not available)
- Primary completion
- Nov 3, 2020 (Actual)
- Completion
- Jul 19, 2023 (Actual)
- Last update posted
- May 11, 2025
2016 – 2023
United States locations
- U.S. sites
- 13
- U.S. states
- 10
- U.S. cities
- 13
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Children's Hospital Los Angeles | Los Angeles | California | 90027 | — |
| Stanford Lucile Packard Children's Hospital | Palo Alto | California | 94304 | — |
| UCSF | San Francisco | California | 94123 | — |
| Children's Hospital Colorado | Aurora | Colorado | 80045 | — |
| Boston Children's Hospital | Boston | Massachusetts | 02115 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| Cohen Children's Medical Center | Queens | New York | 11040 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| Children's Hospital of Philadelphia | Philadelphia | Pennsylvania | 19104 | — |
| UT Southwestern Medical Center | Dallas | Texas | 75390 | — |
| Texas Children's Hospital | Houston | Texas | 77030 | — |
| Fred Hutchinson Cancer Research Center | Seattle | Washington | 98109 | — |
| University of Wisconsin | Madison | Wisconsin | 53792 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02845596, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 11, 2025 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02845596 live on ClinicalTrials.gov.