ClinicalTrials.gov record
Completed Phase 3 Interventional Results available

A Study of Nivolumab + Chemotherapy or Nivolumab + Ipilimumab Versus Chemotherapy in Non-Small Cell Lung Cancer (NSCLC) Participants With Epidermal Growth Factor Receptor (EGFR) Mutation Who Failed 1L or 2L EGFR Tyrosine Kinase Inhibitor (TKI) Therapy

ClinicalTrials.gov ID: NCT02864251

Public ClinicalTrials.gov record NCT02864251. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 5, 2026, 6:21 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Open-Label, Randomized Trial of Nivolumab (BMS-936558) Plus Pemetrexed/Platinum or Nivolumab Plus Ipilimumab (BMS-734016) vs Pemetrexed Plus Platinum in Stage IV or Recurrent Non-Small Cell Lung Cancer (NSCLC) Subjects With Epidermal Growth Factor Receptor (EGFR) Mutation Who Failed 1L or 2L EGFR Tyrosine Kinase Inhibitor Therapy

Study identification

NCT ID
NCT02864251
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Bristol-Myers Squibb
Industry
Enrollment
367 participants

Conditions and interventions

Interventions

  • Carboplatin Drug
  • Cisplatin Drug
  • Ipilimumab Biological
  • Nivolumab Biological
  • Pemetrexed Drug

Drug · Biological

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 16, 2017
Primary completion
Jan 19, 2022
Completion
Oct 16, 2022
Last update posted
Sep 27, 2023

2017 – 2022

United States locations

U.S. sites
18
U.S. states
10
U.S. cities
15
Facility City State ZIP Site status
Pacific Shores Medical Group Long Beach California 90808
Local Institution - 0029 Los Angeles California 90017
Local Institution - 0033 Los Angeles California 90095
Local Institution - 0061 Orange California 92868
Torrance Memorial Physican Network Redondo Beach California 90277
Local Institution - 0003 New Haven Connecticut 06520
Local Institution - 0004 Chicago Illinois 60637
Johns Hopkins University Baltimore Maryland 21205
Local Institution - 0002 Boston Massachusetts 02114
Beth Israel Deaconess Medical Center Boston Massachusetts 02215
Dana Farber Cancer Institute Boston Massachusetts 02215
Local Institution - 0064 New York New York 10016
Duke University Medical Center Butner North Carolina 27509-1626
Fox Chase Cancer Center Philadelphia Pennsylvania 19111
Texas Health Physicians Group Arlington Texas 76012
Baylor Scott and White Research Institute Temple Texas 76508
Local Institution - 0063 Tyler Texas 75701
Local Institution - 0001 Salt Lake City Utah 84112

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 91 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02864251, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 27, 2023 · Synced May 5, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02864251 live on ClinicalTrials.gov.

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