Tepotinib Phase II in NSCLC Harboring MET Alterations (VISION)
Public ClinicalTrials.gov record NCT02864992. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II Single-arm Trial to Investigate Tepotinib in Advanced (Locally Advanced or Metastatic) Non-small Cell Lung Cancer With METex14 Skipping Alterations or MET Amplification (VISION)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study looked at how effective the study drug (tepotinib) was at stopping the growth and spread of lung cancer. This study also measures a number of other things including safety of the study drug and the side effects, how body processes the study drug, or how the study drug affects your quality of life. The study also has an optional pharmacogenetic research part. Pharmacogenetic research is an important way to try to understand the role of genetics in human disease and how genes impact the effectiveness of drugs, because differences in genes can change the way a person responds to a particular drug.
Study identification
- NCT ID
- NCT02864992
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 337 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 13, 2016 (Actual)
- Primary completion
- May 16, 2022 (Actual)
- Completion
- Aug 31, 2026 (Estimated)
- Last update posted
- Jul 14, 2026
2016 – 2026
United States locations
- U.S. sites
- 39
- U.S. states
- 16
- U.S. cities
- 33
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| City of Hope Cancer Center | Duarte | California | 91010 | — |
| California Cancer Associates for Research & Excellence, Inc. | Encinitas | California | 92024 | — |
| St. Joseph Hospital | Orange | California | 92868-4225 | — |
| Torrance Health Association | Redondo Beach | California | 90277 | — |
| St Joseph Heritage Healthcare | Santa Rosa | California | 95403 | — |
| Rocky Mountain Cancer Centers, LLP | Denver | Colorado | 80218 | — |
| Holy Cross Hospital Inc. | Fort Lauderdale | Florida | 33308 | — |
| H. Lee Moffitt Cancer Center and Research Institute, Inc | Tampa | Florida | 33612-9497 | — |
| University Cancer & Blood Center, LLC | Athens | Georgia | 30607 | — |
| Winship Cancer Institute | Atlanta | Georgia | 30322 | — |
| University of Chicago Medical Center | Chicago | Illinois | 60637 | — |
| Ingalls Hospital | Harvey | Illinois | 60426-3558 | — |
| Community Regional Cancer Care | Indianapolis | Indiana | 46250 | — |
| Center for Cancer and Blood Disorders | Bethesda | Maryland | 20817 | — |
| For Recruiting Locations in the United States, please Contact U.S. Medical Information | Rockland | Massachusetts | — | — |
| St. Louis Cancer Care, LLP | Bridgeton | Missouri | 63044 | — |
| Saint Louis University Cancer Center | St Louis | Missouri | 63110 | — |
| Saint Louis University | St Louis | Missouri | 63110 | — |
| Summit Medical Group, P.A. | Berkeley Heights | New Jersey | 07922 | — |
| Summit Medical Group | Berkeley Heights | New Jersey | 07922 | — |
| Regional Cancer Care Associates East Brunswick | East Brunswick | New Jersey | 08816 | — |
| Somerset Hematology Oncology Associates - Somerville Location | East Brunswick | New Jersey | 8816 | — |
| Hackensack University Medical Center PARTNER | Hackensack | New Jersey | 07601 | — |
| Prospect Medical Offices, LLC | Midland Park | New Jersey | 07432 | — |
| The Valley Hospital | Ridgewood | New Jersey | 07450 | — |
| Memorial Sloan Kettering Cancer Center - Commack | Commack | New York | 11725 | — |
| Memorial Sloan Kettering Cancer Center, West Harrison Regional Outpatient Pavilion | Harrison | New York | 10604 | — |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10022 | — |
| UC Health Clinical Trials Office | Cincinnati | Ohio | 45229 | — |
| University of Cincinnati - PARENT | Cincinnati | Ohio | 45267-0502 | — |
| Tennessee Oncology | Nashville | Tennessee | 37203 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | — |
| Texas Oncology, P.A. - Austin | Austin | Texas | 78731 | — |
| Texas Oncology, PA | Beaumont | Texas | 77702-1449 | — |
| University of Texas MD Anderson Cancer Center | Houston | Texas | 77030 | — |
| Virginia Cancer Specialists, PC | Fairfax | Virginia | 22031 | — |
| Swedish Medical Center | Seattle | Washington | 98104 | — |
| Wenatchee Valley Hospital & Clinics - ATTN: Jay Johnson | Wenatchee | Washington | 98801 | — |
| Wenatchee Valley Medical Center Oncology | Wenatchee | Washington | 98801 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 137 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02864992, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 14, 2026 · Synced Oct 19, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02864992 live on ClinicalTrials.gov.