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Completed Phase 3 Interventional Accepts healthy volunteers

Investigating Gains in Neurocognition in an Intervention Trial of Exercise

ClinicalTrials.gov ID: NCT02875301

Public ClinicalTrials.gov record NCT02875301. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 5, 2026, 8:10 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This randomized control trial will examine whether a 12 month monitored exercise intervention improves brain health in cognitively normal older adults. This trial will also address several important unanswered questions: (1) Are the recommended public health guidelines of 150 minutes/week of exercise sufficient for improving cognitive performance? (2) Does exercise influence brain structure and/or function? (3) Is there a dose-response effect of exercise on the above variables such that greater amounts of exercise brings about greater benefits in cognitive and brain health? (4) What are the mechanisms by which exercise influences brain health? and (5) What factors attenuate or magnify the effects of exercise on brain and cognitive health and contribute to the individual variability in intervention outcomes?

Study identification

NCT ID
NCT02875301
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
University of Pittsburgh
Other
Enrollment
648 participants

Conditions and interventions

Interventions

Behavioral

Eligibility (public fields only)

Age range
65 Years to 80 Years
Sex
All
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 5, 2017
Primary completion
Apr 10, 2023
Completion
Apr 10, 2023
Last update posted
Jun 13, 2024

2017 – 2023

United States locations

U.S. sites
5
U.S. states
4
U.S. cities
4
Facility City State ZIP Site status
University of Illinois Champaign Illinois 15218
University of Kansas Kansas City Kansas 66205
Northeastern University Boston Massachusetts 02115
University of Pittsburgh Pittsburgh Pennsylvania 15213
Carnegie Mellon University Pittsburgh Pennsylvania 51260

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02875301, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 13, 2024 · Synced Sep 5, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02875301 live on ClinicalTrials.gov.

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