Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure With Preserved Ejection Fraction

ClinicalTrials.gov ID: NCT02901184

Public ClinicalTrials.gov record NCT02901184. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 8, 2026, 8:10 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure With Preserved Ejection Fraction, SPIRRIT-HFPEF

Study identification

NCT ID: NCT02901184
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 3
Lead sponsor: Uppsala University; Other
Enrollment: 2,000 participants

Conditions and interventions

Conditions

Heart Failure With Preserved Ejection Fraction

Interventions

Spironolactone Drug
Standard care Other

Drug · Other

Eligibility (public fields only)

Age range: 50 Years to 99 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Nov 22, 2017
Primary completion: Nov 30, 2026
Completion: Nov 30, 2026
Last update posted: Oct 21, 2024

2017 – 2026

United States locations

U.S. sites: 38
U.S. states: 20
U.S. cities: 37

Facility	City	State	ZIP	Site status
Advanced Cardiovascular LLC	Alexander City	Alabama	35010	Terminated
University of Alabama at Birmingham	Birmingham	Alabama	35294	Terminated
Banner - University Medical Group	Tucson	Arizona	85724	Terminated
MedStar Cardiovascular Research Network	Washington D.C.	District of Columbia	20010	Terminated
Howard University Hospital	Washington D.C.	District of Columbia	20060	Terminated
Holy Cross Hospital	Fort Lauderdale	Florida	33308	Terminated
Piedmont Atlanta Hospital	Atlanta	Georgia	30309	Terminated
Wellstar Health System, Inc.	Marietta	Georgia	30060	Terminated
Queens Medical Center	Honolulu	Hawaii	96813	Terminated
Fox Valley Clinical Research Center, LLC	Aurora	Illinois	60506-1400	Terminated
University of Illinois at Chicago	Chicago	Illinois	60612	Terminated
Alexian Brothers Medical Center	Elk Grove Village	Illinois	60007	Terminated
Methodist Medical Center of Illinois	Peoria	Illinois	61636	Terminated
St. Vincent Medical Group	Indianapolis	Indiana	46260	Terminated
Ochsner Medical Center	New Orleans	Louisiana	85724	Terminated
Shady Grove Adventist Hospital	Rockville	Maryland	20850	Terminated
Brigham and Women's Hospital	Boston	Massachusetts	02115	Terminated
Pentucket Medical Associates	Haverhill	Massachusetts	01830	Terminated
Charles River Medical Associates	Natick	Massachusetts	01760	Terminated
Newton-Wellesley Hospital	Newton	Massachusetts	02462	Terminated
University of Michigan Medical Center	Ann Arbor	Michigan	48109	Terminated
Ascension Genesys Hospital	Grand Blanc	Michigan	48439	Terminated
The Heart House Haddon Heights	Haddon Heights	New Jersey	08035	Terminated
Rutgers University - Robert Wood Johnson Medical School	New Brunswick	New Jersey	08901	Terminated
University of New Mexico Health Science Center	Albuquerque	New Mexico	87131	Terminated
University at Buffalo	Buffalo	New York	14203	Terminated
Northwell Health - Manhasset	Manhasset	New York	11030	Terminated
Mount Sinai Medical Cente	New York	New York	10029	Terminated
Mid Carolina Cardiology Research	Charlotte	North Carolina	28204	Terminated
Duke University	Durham	North Carolina	27710-4000	Terminated
University of Cincinnati Medical Center	Cincinnati	Ohio	45267-0542	Terminated
Penn State Milton S Hershey Medical Center	Hershey	Pennsylvania	17033	Terminated
Jefferson University Hospital	Philadelphia	Pennsylvania	19107	Terminated
University of Pittsburgh Medical Center	Pittsburgh	Pennsylvania	15213	Terminated
Stern Cardiovascular Center	Germantown	Tennessee	38138	Terminated
Baylor University Medical Center	Dallas	Texas	75246	Terminated
University of Miami Hospital	Miami	Texas	33136	Terminated
University of Texas Health Science Center at San Antonio	San Antonio	Texas	78229	Terminated

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 40 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT02901184, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Oct 21, 2024 · Synced May 8, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02901184 live on ClinicalTrials.gov.

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