ClinicalTrials.gov record
Prospective ARNI vs ACE Inhibitor Trial to DetermIne Superiority in Reducing Heart Failure Events After MI
ClinicalTrials.gov ID: NCT02924727
Public ClinicalTrials.gov record NCT02924727. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 19, 2026, 11:47 AM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multi-center, Randomized, Double-blind, Active-controlled, Parallel-group Phase 3 Study to Evaluate the Efficacy and Safety of LCZ696 Compared to Ramipril on Morbidity and Mortality in High Risk Patients Following an Acute Myocardial Infarction (AMI)
Study identification
- NCT ID
- NCT02924727
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Novartis Pharmaceuticals
- Industry
- Enrollment
- 5,669 participants
Conditions and interventions
Conditions
Interventions
- LCZ696 (sacubitril/valsartan) Drug
- Placebo of LCZ696 Drug
- Placebo of ramipril Drug
- Placebo of valsartan Drug
- Ramipril Drug
- Valsartan Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 8, 2016
- Primary completion
- Feb 25, 2021
- Completion
- Feb 25, 2021
- Last update posted
- Jun 21, 2023
2016 – 2021
United States locations
- U.S. sites
- 81
- U.S. states
- 30
- U.S. cities
- 77
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Novartis Investigative Site | Birmingham | Alabama | 35243 | — |
| Novartis Investigative Site | Birmingham | Alabama | 35294-2041 | — |
| Novartis Investigative Site | Huntsville | Alabama | 35801 | — |
| Novartis Investigative Site | Gilbert | Arizona | 85297 | — |
| Novartis Investigative Site | Bakersfield | California | 93301 | — |
| Novartis Investigative Site | Carmichael | California | 95608 | — |
| Novartis Investigative Site | Los Alamitos | California | 90720 | — |
| Novartis Investigative Site | Northridge | California | 91325 | — |
| Novartis Investigative Site | Orange | California | 92868 | — |
| Novartis Investigative Site | San Francisco | California | 94143 | — |
| Novartis Investigative Site | Sylmar | California | 91342 | — |
| Novartis Investigative Site | Brandon | Florida | 33511 | — |
| Novartis Investigative Site | Hollywood | Florida | 33312 | — |
| Novartis Investigative Site | Jacksonville Beach | Florida | 32050 | — |
| Novartis Investigative Site | Ocala | Florida | 34480 | — |
| Novartis Investigative Site | Cumming | Georgia | 30041 | — |
| Novartis Investigative Site | Johns Creek | Georgia | 30024 | — |
| Novartis Investigative Site | Thomasville | Georgia | 31792 | — |
| Novartis Investigative Site | Boise | Idaho | 83702 | — |
| Novartis Investigative Site | Coeur d'Alene | Idaho | 83814 | — |
| Novartis Investigative Site | Muncie | Indiana | 47303-3400 | — |
| Novartis Investigative Site | Munster | Indiana | 46321 | — |
| Novartis Investigative Site | Richmond | Indiana | 47374 | — |
| Novartis Investigative Site | Iowa City | Iowa | 52242 | — |
| Novartis Investigative Site | Alexandria | Louisiana | 71301 | — |
| Novartis Investigative Site | Baton Rouge | Louisiana | 70808 | — |
| Novartis Investigative Site | Covington | Louisiana | 70433 | — |
| Novartis Investigative Site | Hammond | Louisiana | 70403 | — |
| Novartis Investigative Site | Slidell | Louisiana | 70458 | — |
| Novartis Investigative Site | Bangor | Maine | 04401 | — |
| Novartis Investigative Site | Baltimore | Maryland | 21201 | — |
| Novartis Investigative Site | Baltimore | Maryland | 21218 | — |
| Novartis Investigative Site | Rockville | Maryland | 20850 | — |
| Novartis Investigative Site | Detroit | Michigan | 48201 | — |
| Novartis Investigative Site | Kalamazoo | Michigan | 49008 | — |
| Novartis Investigative Site | Lansing | Michigan | 48912 | — |
| Novartis Investigative Site | Petoskey | Michigan | 49770 | — |
| Novartis Investigative Site | Saginaw | Michigan | 48601 | — |
| Novartis Investigative Site | Southfield | Michigan | 48075 | — |
| Novartis Investigative Site | Duluth | Minnesota | 55805 | — |
| Novartis Investigative Site | Robbinsdale | Minnesota | 55422 | — |
| Novartis Investigative Site | Saint Cloud | Minnesota | 56303 | — |
| Novartis Investigative Site | Saint Paul | Minnesota | 55101 | — |
| Novartis Investigative Site | Hattiesburg | Mississippi | 39401 | — |
| Novartis Investigative Site | Jackson | Mississippi | 39216 | — |
| Novartis Investigative Site | Lee's Summit | Missouri | 64064 | — |
| Novartis Investigative Site | North Kansas City | Missouri | 64116 | — |
| Novartis Investigative Site | Springfield | Missouri | 65804 | — |
| Novartis Investigative Site | Lincoln | Nebraska | 68506 | — |
| Novartis Investigative Site | Lincoln | Nebraska | 68526 | — |
| Novartis Investigative Site | Omaha | Nebraska | 68114 | — |
| Novartis Investigative Site | Lebanon | New Hampshire | 03756 | — |
| Novartis Investigative Site | Hackensack | New Jersey | 07601 | — |
| Novartis Investigative Site | Flushing | New York | 11355 | — |
| Novartis Investigative Site | New York | New York | 10016 | — |
| Novartis Investigative Site | New York | New York | 10029 | — |
| Novartis Investigative Site | Valhalla | New York | 10595 | — |
| Novartis Investigative Site | Chapel Hill | North Carolina | 27599 | — |
| Novartis Investigative Site | Charlotte | North Carolina | 28204 | — |
| Novartis Investigative Site | Durham | North Carolina | 27710 | — |
| Novartis Investigative Site | Grand Forks | North Dakota | 58201 | — |
| Novartis Investigative Site | Canton | Ohio | 44710 | — |
| Novartis Investigative Site | Cincinnati | Ohio | 45220 | — |
| Novartis Investigative Site | Medford | Oregon | 97504 | — |
| Novartis Investigative Site | Erie | Pennsylvania | 16550 | — |
| Novartis Investigative Site | Hershey | Pennsylvania | 17033 | — |
| Novartis Investigative Site | York | Pennsylvania | 17403 | — |
| Novartis Investigative Site | Charleston | South Carolina | 29403 | — |
| Novartis Investigative Site | Columbia | South Carolina | 29203 | — |
| Novartis Investigative Site | Greenville | South Carolina | 29607 | — |
| Novartis Investigative Site | Rapid City | South Dakota | 57701 | — |
| Novartis Investigative Site | Knoxville | Tennessee | 37917 | — |
| Novartis Investigative Site | Nashville | Tennessee | 37212 | — |
| Novartis Investigative Site | Dallas | Texas | 75226 | — |
| Novartis Investigative Site | Houston | Texas | 77030 | — |
| Novartis Investigative Site | Webster | Texas | 77598 | — |
| Novartis Investigative Site | Danville | Virginia | 24541 | — |
| Novartis Investigative Site | Falls Church | Virginia | 22042 | — |
| Novartis Investigative Site | Lynchburg | Virginia | 24501 | — |
| Novartis Investigative Site | Manassas | Virginia | 20109 | — |
| Novartis Investigative Site | Bellevue | Washington | 98004 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 405 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02924727, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 21, 2023 · Synced May 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02924727 live on ClinicalTrials.gov.