A Study of BR Alone Versus in Combination With Acalabrutinib in Subjects With Previously Untreated MCL
Public ClinicalTrials.gov record NCT02972840. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-blind, Placebo-controlled, Multicenter Study of Bendamustine and Rituximab (BR) Alone Versus in Combination With Acalabrutinib (ACP-196) in Subjects With Previously Untreated Mantle Cell Lymphoma
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study is evaluating the efficacy of acalabrutinib in combination with bendamustine and rituximab (BR) compared with placebo plus BR in subjects with previously untreated mantle cell lymphoma.
Study identification
- NCT ID
- NCT02972840
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 635 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 65 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 5, 2017 (Actual)
- Primary completion
- Feb 15, 2027 (Estimated)
- Completion
- Feb 15, 2027 (Estimated)
- Last update posted
- Oct 8, 2026
2017 – 2027
United States locations
- U.S. sites
- 32
- U.S. states
- 20
- U.S. cities
- 30
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Tucson | Arizona | 85719 | — |
| Research Site | Downey | California | 90241 | — |
| Research Site | Santa Monica | California | 90404 | — |
| Research Site | New Haven | Connecticut | 06510 | — |
| Research Site | Washington D.C. | District of Columbia | 20007 | — |
| Research Site | Tallahassee | Florida | 32308-5304 | — |
| Research Site | West Palm Beach | Florida | 33401 | — |
| Research Site | Marietta | Georgia | 30060 | — |
| Research Site | Westwood | Kansas | 66205 | — |
| Research Site | Louisville | Kentucky | 40207 | — |
| Research Site | Ann Arbor | Michigan | 48109 | — |
| Research Site | Rochester | Minnesota | 55905-0001 | — |
| Research Site | Kansas City | Missouri | 64132 | — |
| Research Site | St Louis | Missouri | 63110 | — |
| Research Site | Hackensack | New Jersey | 07601 | — |
| Research Site | Morristown | New Jersey | 07960 | — |
| Research Site | Hawthorne | New York | 10532 | — |
| Research Site | Lake Success | New York | 11042 | — |
| Research Site | Portland | Oregon | 97239 | — |
| Research Site | Charleston | South Carolina | 29425 | — |
| Research Site | Greenville | South Carolina | 29615 | — |
| Research Site | Chattanooga | Tennessee | 37404 | — |
| Research Site | Nashville | Tennessee | 37203 | — |
| Research Site | Houston | Texas | 77030 | — |
| Research Site | San Antonio | Texas | 78217 | — |
| Research Site | Tyler | Texas | 75702 | — |
| Research Site | Charlottesville | Virginia | 22908 | — |
| Research Site | Fort Belvoir | Virginia | 22060 | — |
| Research Site | Seattle | Washington | 98108 | — |
| Research Site | Seattle | Washington | 98109 | — |
| Research Site | Seattle | Washington | 98122 | — |
| Research Site | Morgantown | West Virginia | 26506 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 196 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02972840, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 8, 2026 · Synced Oct 24, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02972840 live on ClinicalTrials.gov.