ClinicalTrials.gov record
Completed Phase 4 Interventional

Comparative Effectiveness Research Trial for Antidepressant Incomplete and Non-responders With TRD

ClinicalTrials.gov ID: NCT02977299

Public ClinicalTrials.gov record NCT02977299. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 7, 2026, 9:04 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Augmentation Versus Switch: Comparative Effectiveness Research Trial for Antidepressant Incomplete and Non-responders With Treatment Resistant Depression (ASCERTAIN-TRD)

Study identification

NCT ID
NCT02977299
Recruitment status
Completed
Study type
Interventional
Phase
Phase 4
Lead sponsor
Massachusetts General Hospital
Other
Enrollment
278 participants

Conditions and interventions

Interventions

  • Aripiprazole Drug
  • Repetitive transcranial magnetic stimulation (rTMS) Device
  • Venlafaxine XR Drug

Drug · Device

Eligibility (public fields only)

Age range
18 Years to 80 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 30, 2017
Primary completion
Apr 23, 2022
Completion
Apr 23, 2022
Last update posted
Apr 26, 2022

2017 – 2022

United States locations

U.S. sites
11
U.S. states
9
U.S. cities
11
Facility City State ZIP Site status
The University of Alabama School of Medicine Birmingham Alabama 35294
Pacific Institute of Medical Research Los Angeles California 90095
Stanford University Stanford California 94305
University of South Florida Tampa Florida 33613
Northwestern University, Feinberg School of Medicine Chicago Illinois 60611
New York University New York New York 10003
University of Cincinnati Cincinnati Ohio 45219
University of Pennsylvania Philadelphia Pennsylvania 19104
Roper St. Francis Hospital Charleston South Carolina 29425
University of Texas Southwestern Medical Center Dallas Texas 75390
Baylor College of Medicine Houston Texas 77030

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02977299, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 26, 2022 · Synced May 7, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02977299 live on ClinicalTrials.gov.

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