EARLY TAVR: Evaluation of TAVR Compared to Surveillance for Patients With Asymptomatic Severe Aortic Stenosis
Public ClinicalTrials.gov record NCT03042104. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Evaluation of Transcatheter Aortic Valve Replacement Compared to Surveillance for Patients With Asymptomatic Severe Aortic Stenosis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will evaluate the safety and effectiveness of the Edwards SAPIEN 3/SAPIEN 3 Ultra Transcatheter Heart Valve (THV) compared with clinical surveillance (CS) in asymptomatic patients with severe, calcific aortic stenosis.
Study identification
- NCT ID
- NCT03042104
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 901 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 65 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 12, 2017 (Actual)
- Primary completion
- Mar 31, 2024 (Actual)
- Completion
- Mar 2032 (Estimated)
- Last update posted
- May 13, 2024
2017 – 2032
United States locations
- U.S. sites
- 74
- U.S. states
- 32
- U.S. cities
- 65
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Banner University Medical Center | Phoenix | Arizona | 85006 | — |
| Mills Peninsula Health Services | Burlingame | California | 94010 | — |
| Cedars-Sinai Medical Center | Los Angeles | California | 90048 | — |
| Hoag Memorial Hospital Presbyterian | Newport Beach | California | 92663 | — |
| Huntington Hospital | Pasadena | California | 91105 | — |
| UC Davis Medical Center | Sacramento | California | 95817 | — |
| Kaiser San Francisco Medical Center | San Francisco | California | 94115 | — |
| Stanford Hospital and Clinics Palo Alto | Stanford | California | 94305 | — |
| UC Health Northern Colorado (Medical Center of the Rockies) | Loveland | Colorado | 80538 | — |
| Yale University | New Haven | Connecticut | 06510 | — |
| Washington Hospital Center DC | Washington D.C. | District of Columbia | 20010 | — |
| The Cardiac & Vascular Institute Research Foundation | Gainesville | Florida | 32605 | — |
| University of Florida | Gainesville | Florida | 32615 | — |
| Piedmont Heart Institute | Atlanta | Georgia | 30309 | — |
| Emory University | Atlanta | Georgia | 30322 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| Rush University Medical Center Chicago | Chicago | Illinois | 60612 | — |
| NorthShore University HealthSystem Research Institution | Evanston | Illinois | 60201 | — |
| Alexian Brothers Hospital Network | Lisle | Illinois | 60532 | — |
| Prairie Education and Research Cooperative | Springfield | Illinois | 62701 | — |
| University of Iowa Hospitals and Clinics | Iowa City | Iowa | 52242 | — |
| Iowa Heart Center | West Des Moines | Iowa | 50266 | — |
| Cardiovascular Research Institute of Kansas | Wichita | Kansas | 67226 | — |
| Ochsner Clinic Foundation | New Orleans | Louisiana | 70121 | — |
| Maine Medical Center | Portland | Maine | 04102 | — |
| University of Maryland Medical Center | Baltimore | Maryland | 21201 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| Cape Cod Hospital | Hyannis | Massachusetts | 02601 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| Minneapolis Heart Institute | Minneapolis | Minnesota | 55407 | — |
| University of Minnesota Medical Center | Minneapolis | Minnesota | 55455 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| CentraCare Heart | Saint Cloud | Minnesota | 56303 | — |
| Saint Luke's Hospital of Kansas City Mid America | Kansas City | Missouri | 64111 | — |
| St. Patrick Hospital | Missoula | Montana | 59802 | — |
| Mary Hitchcock Memorial Hospital | Lebanon | New Hampshire | 03756 | — |
| Atlantic Health System Hospital Corp - Morristown Medical Center | Morristown | New Jersey | 07960 | — |
| Newark Beth Israel Medical Center | Newark | New Jersey | 07112 | — |
| Rutgers Robert Wood Johnson Medical School | Piscataway | New Jersey | 08854 | — |
| Albany Medical College | Albany | New York | 12211 | — |
| University at Buffalo - Kaleida Health | Buffalo | New York | 14203 | — |
| NYU Langone Hosptial - Long Island | Mineola | New York | 11501 | — |
| New York University Langone Medical Center | New York | New York | 10016 | — |
| Columbia University Medical Center/ New York Presbyterian Hospital | New York | New York | 10032 | — |
| Cornell University | New York | New York | 10065 | — |
| Rochester General Hospital | Rochester | New York | 14621 | — |
| Stony Brook University Medical Center | Stony Brook | New York | 11794 | — |
| Montefiore Medical Center | The Bronx | New York | 10467 | — |
| Carolina's Health System | Charlotte | North Carolina | 28203 | — |
| NC Heart and Vascular (Rex Hospital) | Raleigh | North Carolina | 27607 | — |
| The Christ Hospital, Cincinnati | Cincinnati | Ohio | 45219 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| Mount Carmel Health System | Columbus | Ohio | 43213 | — |
| The Ohio Health Research Institute | Columbus | Ohio | 43214 | — |
| Kaiser Portland | Clackamas | Oregon | 97015 | — |
| Pinnacle Health | Harrisburg | Pennsylvania | 17101 | — |
| Allegheny - Singer Research Institute | Pittsburgh | Pennsylvania | 15212 | — |
| Lankenau Medical Center | Wynnewood | Pennsylvania | 19096 | — |
| York Hospital | York | Pennsylvania | 17403 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | — |
| The Heart Hospital Baylor Plano | Dallas | Texas | 75093 | — |
| Texas Health Physician Group | Dallas | Texas | 75231 | — |
| University of Texas Health Science Center at Houston | Houston | Texas | 77030 | — |
| Intermountain Medical Center Salt Lake City | Murray | Utah | 84107 | — |
| University of Virginia | Charlottesville | Virginia | 22908 | — |
| Inova Heart and Vascular Institute (Fairfax Inova) | Falls Church | Virginia | 22042 | — |
| Sentara Cardiovascular Research Institute | Norfolk | Virginia | 23507 | — |
| Carilion Medical Center | Roanoke | Virginia | 24014 | — |
| Providence Everett | Everett | Washington | 98201 | — |
| Swedish Medical Center | Seattle | Washington | 98122 | — |
| University of Washington | Seattle | Washington | 98195 | — |
| Sacred Heart Medical Center | Spokane | Washington | 99204 | — |
| CAMC Clinical Trials Center | Charleston | West Virginia | 25304 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03042104, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 13, 2024 · Synced Oct 24, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03042104 live on ClinicalTrials.gov.