ClinicalTrials.gov record
Safety and Efficacy of Selonsertib in Adults With Nonalcoholic Steatohepatitis (NASH) and Bridging (F3) Fibrosis
ClinicalTrials.gov ID: NCT03053050
Public ClinicalTrials.gov record NCT03053050. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of Selonsertib in Subjects With Nonalcoholic Steatohepatitis (NASH) and Bridging (F3) Fibrosis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objective of this study is to evaluate whether selonsertib (SEL; GS-4997) can cause fibrosis regression and reduce progression to cirrhosis and associated complications in adults with NASH and bridging (F3) fibrosis.
Study identification
- NCT ID
- NCT03053050
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 808 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 70 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 13, 2017 (Actual)
- Primary completion
- Jun 19, 2019 (Actual)
- Completion
- Jun 19, 2019 (Actual)
- Last update posted
- Jun 29, 2020
2017 – 2019
United States locations
- U.S. sites
- 124
- U.S. states
- 33
- U.S. cities
- 98
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Institute of Liver Health | Chandler | Arizona | 85224 | — |
| Banner University Medical Center-Phoenix | Phoenix | Arizona | 85006 | — |
| St. Joseph's Hospital and Medical Center | Phoenix | Arizona | 85013 | — |
| Mayo Clinic | Phoenix | Arizona | 85054 | — |
| University of Arizona | Tucson | Arizona | 85724 | — |
| Baptist Medical Center | Little Rock | Arkansas | 72204 | — |
| Arkansas Gastroenterology | North Little Rock | Arkansas | 72204 | — |
| eStudySite | Chula Vista | California | 91911 | — |
| Southern California Liver Centers | Coronado | California | 92673 | — |
| United Gastroenterologists | Costa Mesa | California | 92626 | — |
| TriWest Research Associates, LLC | El Cajon | California | 92020 | — |
| Fresno Clinical Research Center | Fresno | California | 93720 | — |
| University of California San Diego (UCSD) | La Jolla | California | 92103 | — |
| Ruane Clinical Research Group | Los Angeles | California | 90036 | — |
| Cedars Sinai Medical Center | Los Angeles | California | 90048 | — |
| VA Greater Los Angeles Healthcare System | Los Angeles | California | 90073 | — |
| eStudySite | Oceanside | California | 92056 | — |
| California Liver Institute | Pasadena | California | 91105 | — |
| Inland Empire Liver Foundation | Rialto | California | 92377 | — |
| University of California, Davis Medical Center | Sacramento | California | 95817 | — |
| Medical Associates Research Group | San Diego | California | 92123 | — |
| Kaiser Permanente | San Diego | California | 92514 | — |
| California Pacific Medical Center - Sutter Pacific Medical Foundation San Francisco Center for Liver Disease Dept. of Transplant | San Francisco | California | 94115 | — |
| Mission Gastroenterology and Hepatology | San Francisco | California | 94115 | — |
| University of California San Francisco (UCSF) | San Francisco | California | 94143 | — |
| Silicon Valley Research Institute | San Jose | California | 95128 | — |
| University of Colorado | Aurora | Colorado | 80045 | — |
| Yale University School of Medicine | New Haven | Connecticut | 06510 | — |
| Integrity Clinical Research, LLC | Doral | Florida | 33166 | — |
| UF Hepatology Research at CTRB | Gainesville | Florida | 32610 | — |
| UF Health Jacksonville-Gastroenterology Emerson | Jacksonville | Florida | 32207 | — |
| Florida Research Institute | Lakewood Rch | Florida | 34211 | — |
| Sunrise Medical Research, Inc | Lauderdale Lakes | Florida | 33319 | — |
| Sunrise Research Institute | Miami | Florida | 33130 | — |
| Schiff Center for Liver Diseases/University of Miami | Miami | Florida | 33136 | — |
| Genoma Research Group, Inc | Miami | Florida | 33165 | — |
| Advanced Research Institute | New Port Richey | Florida | 34653 | — |
| Avail Clinical Research, LLC | Orange City | Florida | 32763 | — |
| South Florida Center of Gastroenterology, PA | Wellington | Florida | 33414 | — |
| Florida Medical Clinic, PA | Zephyrhills | Florida | 33540 | — |
| Digestive Healthcare of Georgia | Atlanta | Georgia | 30309 | — |
| Piedmont Transplant Institute | Atlanta | Georgia | 30309 | — |
| Gastrointestinal Specialists of Georgia, PC | Marietta | Georgia | 30060 | — |
| Northwestern Memorial Hospital; Clinical Research Unit | Chicago | Illinois | 60611 | — |
| The University of Chicago Medical Center | Chicago | Illinois | 60615 | — |
| NorthShore University Healthsystem | Glenview | Illinois | 60026 | — |
| Indiana University Health - University Hospital | Indianapolis | Indiana | 46202 | — |
| Indianapolis Gastroenterology Research Foundation | Indianapolis | Indiana | 46237 | — |
| University of Iowa Hospitals and Clinics | Iowa City | Iowa | 52242 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| Gastroenterology Associates of Hazard | Hazard | Kentucky | 41707 | — |
| Delta Research Partners, LLC | Bastrop | Louisiana | 71021 | — |
| Tulane University Health Sciences Center | New Orleans | Louisiana | 70112 | — |
| Ocshner Medical Center | New Orleans | Louisiana | 70121 | — |
| Louisiana Research Center, LLC | Shreveport | Louisiana | 71105 | — |
| Mercy Medical Center | Baltimore | Maryland | 21202 | — |
| Walter Reed National Military Medical Center | Bethesda | Maryland | 20889 | — |
| Digestive Disease Associates, PA | Catonsville | Maryland | 21228 | — |
| Meritus Center for Clinical Research | Hagerstown | Maryland | 21472 | — |
| Henry Ford Health System | Detroit | Michigan | 48202 | — |
| Gastroenterology Associates of Western Michigan, P.L.C. | Wyoming | Michigan | 49519 | — |
| Huron Gastroenterology Associates/Center for Digestive Care | Ypsilanti | Michigan | 48197 | — |
| University of Minnesota Medical Center - Fairview | Minneapolis | Minnesota | 55455 | — |
| Mayo Clinic | Rochester | Minnesota | 55095 | — |
| Southern Therapy and Advanced Research LLC (STAR) | Ridgeland | Mississippi | 39157 | — |
| Saint Luke's Hospital of Kansas City | Kansas City | Missouri | 64111 | — |
| Kansas City Gastroenterology and Hepatology | Kansas City | Missouri | 64131 | — |
| Saint Louis University | St Louis | Missouri | 63104 | — |
| eStudySite | Las Vegas | Nevada | 89109 | — |
| Rutgers New Jersey Medical School- Doctors Office Center | Newark | New Jersey | 07102 | — |
| University of Buffalo, Clinical and Translational Research Center | Buffalo | New York | 14230 | — |
| Northwell Health - Sandra Atlas Bass Center for Liver Diseases | Manhasset | New York | 11030 | — |
| Icahn School of Medicine at Mount Sinai Beth Israel | New York | New York | 10003 | — |
| University of Rochester Medical Center | Rochester | New York | 14642 | — |
| University of North Carolina at Chapel Hill / UNC School of Medicine | Chapel Hill | North Carolina | 27599 | — |
| Duke University Medical Center - Duke South Clinics | Durham | North Carolina | 27710 | — |
| Cumberland Research Associates, LLC | Fayetteville | North Carolina | 28304 | — |
| Triad Clinical Trials LLC | Greensboro | North Carolina | 27410 | — |
| Piedmont HealthCare, d/b/a Carolinas Center for Liver Disease | Huntersville | North Carolina | 28078 | — |
| PMG Research of Rocky Mount, LLC | Rocky Mount | North Carolina | 27804 | — |
| Piedmont HealthCare, d/b/a Carolinas Center for Liver Disease | Statesville | North Carolina | 28625 | — |
| Digestive Health Specialists, PA | Winston-Salem | North Carolina | 27103 | — |
| Consultants for Clinical Research | Cincinnati | Ohio | 45249 | — |
| UC Health/Holmes Hospital | Cincinnati | Ohio | 45267 | — |
| Northeast Clinical Research Center, LLC | Bethlehem | Pennsylvania | 18017 | — |
| Hospital of the University of Pennsylvania- Perelman Center for Advanced Medicine | Philadelphia | Pennsylvania | 19104 | — |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | — |
| UPMC - Center for Liver Diseases at the Thomas E. Starlz Institute | Pittsburgh | Pennsylvania | 15213 | — |
| VA Pittsburgh Healthcare System | Pittsburgh | Pennsylvania | 15240 | — |
| eStudySite | Pittsburgh | Pennsylvania | 15251 | — |
| Guthrie Medical Group, PC | Sayre | Pennsylvania | 18840 | — |
| University Gastroenterology | Providence | Rhode Island | 02905 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29245 | — |
| Greenville Health System - Gastroenterology and Liver Center | Greenville | South Carolina | 29605 | — |
| WR-ClinSearch, LLC | Chattanooga | Tennessee | 37421 | — |
| Gastro One | Germantown | Tennessee | 38138 | — |
| Quality Medical Research PLLC | Nashville | Tennessee | 37211 | — |
| Vanderbilt University Medical Center - Digestive Disease Center | Nashville | Tennessee | 37212 | — |
| Texas Clinical Research Institute, LLC | Arlington | Texas | 76012 | — |
| Pinnacle Clinical Research, PLLC | Austin | Texas | 78746 | — |
| Austin Center for Clinical Research | Austin | Texas | 78756 | — |
| The Liver Institute at Methodist Dallas Medical Center | Dallas | Texas | 75203 | — |
| Texas Digestive Disease Consultants | Dallas | Texas | 75246 | — |
| Baylor Scott & White All Saints Medical Center | Fort Worth | Texas | 76104 | — |
| Kelsey-Seybold Clinic | Houston | Texas | 77025 | — |
| Baylor College of Medicine - Advanced Liver Therapies | Houston | Texas | 77030 | — |
| VAMC & Baylor College | Houston | Texas | 77030 | — |
| Pinnacle Clinical Research, PLLC | Live Oak | Texas | 78233 | — |
| American Research Corporation, The Texas Liver Institute | San Antonio | Texas | 78215 | — |
| Intermountain Liver Disease and Transplant Center | Murray | Utah | 84107 | — |
| University of Utah Hospital | Salt Lake City | Utah | 84132 | — |
| The University of Vermont Medical Center | Burlington | Vermont | 05401 | — |
| University of Virginia Medical Center | Charlottesville | Virginia | 22908 | — |
| Verity Research, Inc. | Fairfax | Virginia | 22031 | — |
| Inova Fairfax Medical Campus | Falls Church | Virginia | 22042 | — |
| Emeritas Research Group | Lansdowne Town Center | Virginia | 20716 | — |
| Bon Secours St. Mary's Hospital of Richmond, Inc. d/b/a Bon Secours Liver Institute of Virginia | Newport News | Virginia | 23602 | — |
| Digestive and Liver Disease Specialists | Norfolk | Virginia | 23502 | — |
| Bon Secours St. Mary's Hospital of Richmond, Inc. d/b/a Bon Secours Liver Institute of Virginia | Richmond | Virginia | 23226 | — |
| McGuire VA Medical Center | Richmond | Virginia | 23249 | — |
| Virginia Commonwealth University | Richmond | Virginia | 23298 | — |
| Virginia Mason | Seattle | Washington | 98101 | — |
| Swedish Organ Transplant and Liver Center | Seattle | Washington | 98104 | — |
| Froedtert Memorial Lutheran Hospital | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 174 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03053050, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 29, 2020 · Synced Oct 25, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03053050 live on ClinicalTrials.gov.