ClinicalTrials.gov record
Safety and Efficacy of Selonsertib in Adults With Compensated Cirrhosis Due to Nonalcoholic Steatohepatitis (NASH)
ClinicalTrials.gov ID: NCT03053063
Public ClinicalTrials.gov record NCT03053063. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of Selonsertib in Subjects With Compensated Cirrhosis Due to Nonalcoholic Steatohepatitis (NASH)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objective of this study is to evaluate whether selonsertib (SEL; GS-4997) can cause fibrosis regression and reduce associated complications in adults with cirrhosis due to NASH.
Study identification
- NCT ID
- NCT03053063
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 883 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 70 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 30, 2017 (Actual)
- Primary completion
- May 6, 2019 (Actual)
- Completion
- May 6, 2019 (Actual)
- Last update posted
- May 7, 2020
2017 – 2019
United States locations
- U.S. sites
- 128
- U.S. states
- 32
- U.S. cities
- 96
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Institute of Liver Health | Chandler | Arizona | 85224 | — |
| St. Joseph's Hospital and Medical Center | Phoenix | Arizona | 85013 | — |
| Mayo Clinic | Phoenix | Arizona | 85054 | — |
| Baptist Medical Center | Little Rock | Arkansas | 72204 | — |
| Arkansas Gastroenterology | North Little Rock | Arkansas | 72117 | — |
| Southern California Research Center | Coronado | California | 92118 | — |
| Fresno Clinical Research Center | Fresno | California | 93720 | — |
| Scripps Clinical Research Services | La Jolla | California | 92037 | — |
| University of California, San Diego (Altman Clinical and Translational Research Center) | La Jolla | California | 92093 | — |
| Ruane Clinical Research Group | Los Angeles | California | 90036 | — |
| Cedars-Sinai Medical Center | Los Angeles | California | 90048 | — |
| Veterans Affair Greater Los Angeles Healthcare System, West Los Angeles VA Medical Center | Los Angeles | California | 90073 | — |
| California Liver Research Institute | Pasadena | California | 91105 | — |
| Huntington Medical Research Institutes (HMRI) Liver Center | Pasadena | California | 91105 | — |
| Inland Empire Liver Foundation | Rialto | California | 92377 | — |
| University of California, Davis Medical Center | Sacramento | California | 95817 | — |
| Research and Education, Inc. | San Diego | California | 92105 | — |
| Medical Associates Research Group | San Diego | California | 92123 | — |
| Kaiser Permanente | San Diego | California | 92514 | — |
| California Pacific Medical Center - Sutter Pacific Medical Foundation San Francisco Center for Liver Disease Dept. of Transplant | San Francisco | California | 94115 | — |
| eStudySite | San Francisco | California | 94115 | — |
| University of California, San Francisco-Liver Clinic | San Francisco | California | 94143 | — |
| Island View Gastroenterology Associates- Ventura | Ventura | California | 93003 | — |
| University of Colorado Denver and Hospital | Aurora | Colorado | 80045 | — |
| South Denver Gastroenterology, PC | Englewood | Colorado | 80113 | — |
| Integrity Clinical Research, LLC | Doral | Florida | 33166 | — |
| University of Florida Hepatology Research at CTRB | Gainesville | Florida | 32610 | — |
| Clinical Research of Homestead | Homestead | Florida | 33030 | — |
| Nature Coast Clinical Research | Inverness | Florida | 34452 | — |
| Florida Research Institute | Lakewood Rch | Florida | 34211 | — |
| Schiff Center for Liver Diseases/University of Miami | Miami | Florida | 33136 | — |
| Florida Hospital Transplant Institute | Orlando | Florida | 32804 | — |
| IMIC Inc | Palmetto | Florida | 33157 | — |
| South Florida Center of Gastroenterology, PA | Wellington | Florida | 33414 | — |
| Cleveland Clinic Florida | Weston | Florida | 33331 | — |
| Florida Medical Clinic, PA | Zephyrhills | Florida | 33540 | — |
| Digestive Healthcare of Georgia | Atlanta | Georgia | 30309 | — |
| Piedmont Transplant Institute | Atlanta | Georgia | 30309 | — |
| Columbus Regional Research Institute | Columbus | Georgia | 31904 | — |
| Gastroenterology Associates of Central Georgia, LLC | Macon | Georgia | 31201 | — |
| Gastrointestinal Specialists of Georgia, PC | Marietta | Georgia | 30060 | — |
| Northwestern Memorial Hospital; Clinical Research Unit | Chicago | Illinois | 60611 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| The University of Chicago Medical Center | Chicago | Illinois | 60615 | — |
| NorthShore University HealthSystem - Glenbrook ACC | Glenview | Illinois | 60026 | — |
| Indiana University Health - University Hospital | Indianapolis | Indiana | 46202 | — |
| Indianapolis Gastroenterology Research Foundation | Indianapolis | Indiana | 46237 | — |
| Iowa Digestive Disease Center, P.C. | Clive | Iowa | 50325 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| Gastroenterology Associates of Hazard | Hazard | Kentucky | 41707 | — |
| University of Louisville Clinical Trials Unit | Louisville | Kentucky | 40202 | — |
| Delta Research Partners | Bastrop | Louisiana | 71021 | — |
| Tulane University Health Sciences Center | New Orleans | Louisiana | 70112 | — |
| Ocshner Medical Center | New Orleans | Louisiana | 70121 | — |
| Louisiana Research Center, LLC | Shreveport | Louisiana | 71105 | — |
| Mercy Medical Center | Baltimore | Maryland | 21202 | — |
| Walter Reed National Military Medical Center | Bethesda | Maryland | 20889 | — |
| Digestive Disease Associates, PA | Catonsville | Maryland | 21228 | — |
| Meritus Center for Clinical Research | Hagerstown | Maryland | 21742 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| University of Massachusetts Medical School | Worcester | Massachusetts | 01655 | — |
| Henry Ford Health System | Detroit | Michigan | 48202 | — |
| Gastroenterology Associates of Western Michigan, P.L.C. | Wyoming | Michigan | 49519 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Southern Therapy and Advanced Research LLC (STAR) | Ridgeland | Mississippi | 39157 | — |
| Saint Luke's Hospital of Kansas City | Kansas City | Missouri | 64111 | — |
| Kansas City Research Institute | Kansas City | Missouri | 64131 | — |
| Saint Louis University | St Louis | Missouri | 63104 | — |
| Rutgers New Jersey Medical School- Doctors Office Center | Newark | New Jersey | 07102 | — |
| AccumetRx Clinical Research | Albuquerque | New Mexico | 87109 | — |
| University of Buffalo, Clinical and Translational Research Center | Buffalo | New York | 14230 | — |
| Northwell Health - Sandra Atlas Bass Center for Liver Diseases | Manhasset | New York | 11030 | — |
| Icahn School of Medicine at Mount Sinai Beth Israel | New York | New York | 10003 | — |
| NYU Langone Medical Center | New York | New York | 10016 | — |
| Weill Cornell Medical College | New York | New York | 10021 | — |
| Icahn School of Medicine at Mount Sinai | New York | New York | 10029 | — |
| University of Rochester Medical Center | Rochester | New York | 14642 | — |
| Montefiore Medical Center | The Bronx | New York | 10467 | — |
| NC TraCS Institute- CTRC, University of North Carolina at Chapel Hill | Chapel Hill | North Carolina | 27599 | — |
| Carolinas HealthCare System Center for Liver Disease | Charlotte | North Carolina | 28204 | — |
| Duke University Medical Center - Duke South Clinics | Durham | North Carolina | 27710 | — |
| Cumberland Research Associates LLC | Fayetteville | North Carolina | 28304 | — |
| Piedmont HealthCare, d/b/a Carolinas Center for Liver Disease | Huntersville | North Carolina | 28078 | — |
| PMG Research of Rocky Mount, LLC | Rocky Mount | North Carolina | 27804 | — |
| Piedmont Healthcare | Statesville | North Carolina | 28677 | — |
| Digestive Health Specialists, PA | Winston-Salem | North Carolina | 27103 | — |
| Consultants for Clinical Research | Cincinnati | Ohio | 45249 | — |
| University of Cincinnati | Cincinnati | Ohio | 45267 | — |
| University Hospitals Cleveland Medical Center | Cleveland | Ohio | 44106 | — |
| Penn State University, The Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033 | — |
| Hospital of the University of Pennsylvania- Perelman Center for Advanced Medicine | Philadelphia | Pennsylvania | 19104 | — |
| Thomas Jefferson University Hospital | Philadelphia | Pennsylvania | 19107 | — |
| UPMC - Center for Liver Diseases at the Thomas E. Starlz Institute | Pittsburgh | Pennsylvania | 15213 | — |
| University Gastroenterology | Providence | Rhode Island | 02905 | — |
| Medical University of South Carolina, University Hospital | Charleston | South Carolina | 29425 | — |
| Greenville Health System Gastroenterology and Liver Center | Greenville | South Carolina | 29605 | — |
| WR-ClinSearch, LLC | Chattanooga | Tennessee | 37421 | — |
| Gastro One | Germantown | Tennessee | 38138 | — |
| Methodist University Hospital/University of Tennessee Health Science Center, Office of Clinical Research | Memphis | Tennessee | 38104 | — |
| Quality Medical Research PLLC | Nashville | Tennessee | 37211 | — |
| Vanderbilt University Medical Center - Digestive Disease Center | Nashville | Tennessee | 37232 | — |
| Texas Clinical Research Institute, LLC | Arlington | Texas | 76012 | — |
| Pinnacle Clinical Research, PLLC | Austin | Texas | 78746 | — |
| Austin Center for Clinical Research | Austin | Texas | 78756 | — |
| The Liver Institute at Methodist Dallas Medical Center | Dallas | Texas | 75203 | — |
| Texas Digestive Disease Consultants | Dallas | Texas | 75246 | — |
| Kelsey-Seybold Clinic | Houston | Texas | 77025 | — |
| Baylor College of Medicine - Advanced Liver Therapies | Houston | Texas | 77030 | — |
| Houston Methodist Hospital | Houston | Texas | 77030 | — |
| Liver Associates of Texas, P.A. | Houston | Texas | 77030 | — |
| Research Specialists of Texas | Houston | Texas | 77030 | — |
| Smith Clinic | Houston | Texas | 77030 | — |
| Pinnacle Clinical Research | Live Oak | Texas | 78233 | — |
| DHAT Research Institute | Richardson | Texas | 75082 | — |
| American Research Corporation, The Texas Liver Institute | San Antonio | Texas | 78215 | — |
| Intermountain Liver Disease and Transplant Clinic | Murray | Utah | 84107 | — |
| University of Utah | Salt Lake City | Utah | 84132 | — |
| The University of Vermont Medical Center | Burlington | Vermont | 05401 | — |
| University of Virginia Medical Center | Charlottesville | Virginia | 22908 | — |
| Inova Fairfax Medical Campus | Falls Church | Virginia | 22042 | — |
| Bon Secours St. Mary's Hospital of Richmond, Inc. d/b/a Bon Secours Liver Institute of Virginia | Newport News | Virginia | 23226 | — |
| Digestive and Liver Disease Specialists | Norfolk | Virginia | 23502 | — |
| McGuire VA Medical Center | Richmond | Virginia | 23249 | — |
| Virginia Commonwealth University | Richmond | Virginia | 23298 | — |
| Virginia Mason | Seattle | Washington | 98101 | — |
| Swedish Organ Transplant and Liver Center | Seattle | Washington | 98104 | — |
| University of Washington | Seattle | Washington | 98195 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 155 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03053063, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 7, 2020 · Synced Oct 24, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03053063 live on ClinicalTrials.gov.