ClinicalTrials.gov record
Active, not recruiting Phase 2 Interventional

Axitinib With or Without Anti-OX40 Antibody PF-04518600 in Treating Patients With Metastatic Kidney Cancer

ClinicalTrials.gov ID: NCT03092856

Public ClinicalTrials.gov record NCT03092856. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 6, 2026, 8:25 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase II Randomized Double Blind Trial of PF-04518600, an OX40 Antibody, in Combination With Axitinib Versus Axitinib in Immune-Checkpoint Inhibitor Exposed Patients With Metastatic Renal Cell Carcinoma

Study identification

NCT ID
NCT03092856
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 2
Lead sponsor
University of Southern California
Other
Enrollment
62 participants

Conditions and interventions

Interventions

  • Anti-OX40 Antibody PF-04518600 Biological
  • Axitinib Drug
  • Laboratory Biomarker Analysis Other
  • Placebo Other

Biological · Drug · Other

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 18, 2017
Primary completion
Jun 29, 2026
Completion
Dec 30, 2026
Last update posted
Dec 16, 2025

2017 – 2026

United States locations

U.S. sites
10
U.S. states
6
U.S. cities
9
Facility City State ZIP Site status
Los Angeles County-USC Medical Center Los Angeles California 90033
USC / Norris Comprehensive Cancer Center Los Angeles California 90033
USC Norris Oncology/Hematology-Newport Beach Newport Beach California 92663
University of California Davis Comprehensive Cancer Center Sacramento California 95817
University of Kansas Cancer Center Kansas City Kansas 66160
Weill Cornell Medical College, New York- Presbyterian Hospital New York New York 10065
Cleveland Clinic Taussig Cancer Institute, Case Comprehensive Cancer Center Cleveland Ohio 44195
Ohio State University Comprehensive Cancer Center Columbus Ohio 43210
University of Pittsburgh Cancer Institute (UPCI) Pittsburgh Pennsylvania 15232
University of Virginia Cancer Center Charlottesville Virginia 22903

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03092856, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 16, 2025 · Synced May 6, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03092856 live on ClinicalTrials.gov.

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