ClinicalTrials.gov record
A Study Comparing Upadacitinib (ABT-494) to Placebo and to Adalimumab in Participants With Psoriatic Arthritis Who Have an Inadequate Response to at Least One Non-Biologic Disease Modifying Anti-Rheumatic Drug (DMARD)
ClinicalTrials.gov ID: NCT03104400
Public ClinicalTrials.gov record NCT03104400. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 20, 2026, 10:02 AM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-Blind, Study Comparing Upadacitinib (ABT-494) to Placebo and to Adalimumab in Subjects With Active Psoriatic Arthritis Who Have a History of Inadequate Response to at Least One Non-Biologic Disease Modifying Anti-Rheumatic Drug (DMARD) - SELECT - PsA 1
Study identification
- NCT ID
- NCT03104400
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- AbbVie
- Industry
- Enrollment
- 1,705 participants
Conditions and interventions
Conditions
Interventions
- Adalimumab Drug
- Placebo to Adalimumab Drug
- Placebo to Upadacitinib Drug
- Upadacitinib Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 26, 2017
- Primary completion
- Sep 25, 2019
- Completion
- Sep 8, 2024
- Last update posted
- Sep 21, 2025
2017 – 2024
United States locations
- U.S. sites
- 114
- U.S. states
- 34
- U.S. cities
- 103
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Rheum Assoc of North Alabama /ID# 163231 | Huntsville | Alabama | 35801 | — |
| SunValley Arthritis Center, Lt /ID# 161221 | Peoria | Arizona | 85381 | — |
| AZ Arthritis and Rheumotology Research, PLLC /ID# 159981 | Phoenix | Arizona | 85032-9306 | — |
| AZ Arthritis and Rheumotology Research, PLLC /ID# 160033 | Phoenix | Arizona | 85032-9306 | — |
| AZ Arthritis and Rheumotology Research, PLLC /ID# 160036 | Phoenix | Arizona | 85032-9306 | — |
| AZ Arthritis & Rheuma Research /ID# 160037 | Phoenix | Arizona | 85032 | — |
| AZ Arth & Rheum Res /ID# 166381 | Tucson | Arizona | 85704 | — |
| Little Rock Diagnostics Clinic /ID# 165161 | Little Rock | Arkansas | 72205 | — |
| Covina Arthritis Clinic /ID# 159891 | Covina | California | 91722 | — |
| St. Joseph Heritage Healthcare /ID# 159980 | Fullerton | California | 92835 | — |
| C.V. Mehta MD, Med Corporation /ID# 161216 | Hemet | California | 92543 | — |
| Care Access Research, Huntingt /ID# 160038 | Huntington Beach | California | 92648 | — |
| Kotha and Kotha /ID# 159823 | La Mesa | California | 91942 | — |
| TriWest Research Associates- La Mesa /ID# 159887 | La Mesa | California | 91942 | — |
| Arthritis & Osteo Medical Ctr /ID# 166760 | La Palma | California | 90623-1728 | — |
| University of California, Los Angeles /ID# 164542 | Los Angeles | California | 90095 | — |
| VA Sacramento Medical Center /ID# 164196 | Mather | California | 95655 | — |
| East Bay Rheumatology Medical /ID# 166382 | San Leandro | California | 94578 | — |
| Inland Rheum Clin Trials Inc. /ID# 159828 | Upland | California | 91786 | — |
| Medvin Clinical Research /ID# 160034 | Whittier | California | 90606 | — |
| Denver Arthritis Clinic /ID# 159873 | Denver | Colorado | 80230 | — |
| Arthritis and Rheum Clin N. CO /ID# 160039 | Fort Collins | Colorado | 80528 | — |
| Colorado Arthritis Associates /ID# 159847 | Lakewood | Colorado | 80228 | — |
| Stamford Therapeutics Consorti /ID# 165131 | Stamford | Connecticut | 06905 | — |
| Clinical Res of West FL, Inc. /ID# 159829 | Clearwater | Florida | 33765 | — |
| International Medical Research - Daytona /ID# 160040 | Daytona Beach | Florida | 32117 | — |
| Omega Research Maitland, LLC /ID# 164193 | DeBary | Florida | 32713-2260 | — |
| LeJenue Research Associates /ID# 170965 | Miami | Florida | 33126 | — |
| Precision Research Org, LLC /ID# 161287 | Miami Lakes | Florida | 33016-1501 | — |
| Medallion Clinical Research Institute, LLC /ID# 161228 | Naples | Florida | 34102 | — |
| Millennium Research /ID# 159822 | Ormond Beach | Florida | 32174 | — |
| Arthritis Center, Inc. /ID# 163465 | Palm Harbor | Florida | 34684 | — |
| Gulf Region Clinical Res Inst /ID# 159851 | Pensacola | Florida | 32514 | — |
| BayCare Medical Group /ID# 159792 | St. Petersburg | Florida | 33705 | — |
| W. Broward Rheum Assoc Inc. /ID# 161388 | Tamarac | Florida | 33321 | — |
| Clinical Research of West Florida, Inc /ID# 160063 | Tampa | Florida | 33606-1246 | — |
| University of South Florida /ID# 161286 | Tampa | Florida | 33612 | — |
| BayCare Medical Group, Inc. /ID# 159879 | Tampa | Florida | 33614-7101 | — |
| Florida Medical Clinic /ID# 159992 | Zephyrhills | Florida | 33542 | — |
| Institute of Arthritis Researc /ID# 165873 | Idaho Falls | Idaho | 83404 | — |
| Advanced Clinical Research /ID# 159894 | Meridian | Idaho | 83642 | — |
| Great Lakes Clinical Trials /ID# 163435 | Chicago | Illinois | 60640 | — |
| OrthoIllinois /ID# 164546 | Rockford | Illinois | 61114-4937 | — |
| Clinical Investigation Specialists - Skokie /ID# 160062 | Skokie | Illinois | 60076 | — |
| Deerbrook Medical Associates /ID# 159804 | Vernon Hills | Illinois | 60061 | — |
| Graves Gilbert Clinic /ID# 161285 | Bowling Green | Kentucky | 42101 | — |
| Four Rivers Clinical Research /ID# 159982 | Paducah | Kentucky | 42001 | — |
| Ochsner Clinic Foundation-New Orleans /ID# 165672 | New Orleans | Louisiana | 70121 | — |
| Johns Hopkins University /ID# 167665 | Baltimore | Maryland | 21224 | — |
| Klein & Associates, M.D., P.A. /ID# 164013 | Cumberland | Maryland | 21502 | — |
| The Center for Rheumatology & Bone Research /ID# 159874 | Wheaton | Maryland | 20902 | — |
| Tufts Medical Center /ID# 165144 | Boston | Massachusetts | 02111 | — |
| Mansfield Health Center /ID# 159805 | Mansfield | Massachusetts | 02048 | — |
| Clinical Pharmacology Study Gr /ID# 158700 | Worcester | Massachusetts | 01605 | — |
| Univ of Michigan Hospitals /ID# 164014 | Ann Arbor | Michigan | 48109 | — |
| Aa Mrc Llc /Id# 159846 | Grand Blanc | Michigan | 48439 | — |
| Advanced Rheumatology, PC /ID# 159893 | Lansing | Michigan | 48910 | — |
| Beals Institute PC /ID# 163128 | Lansing | Michigan | 48917 | — |
| Shores Rheumatology, PC /ID# 159889 | Saint Clair Shores | Michigan | 48081 | — |
| St. Luke's Hospital of Duluth /ID# 165671 | Duluth | Minnesota | 55805 | — |
| Clinvest Research LLC /ID# 161227 | Springfield | Missouri | 65810-2607 | — |
| Clayton Medical Associates dba Saint Louis Rheumatology /ID# 159878 | St Louis | Missouri | 63119-3845 | — |
| Glacier View Research Institut /ID# 167023 | Kalispell | Montana | 59901 | — |
| Westroads Clinical Research /ID# 159979 | Omaha | Nebraska | 68114 | — |
| Dartmouth-Hitchcock Medical Center /ID# 161235 | Lebanon | New Hampshire | 03756 | — |
| Arthritis and Osteoporosis Associates /ID# 159802 | Freehold | New Jersey | 07728 | — |
| Atlantic Coast Research /ID# 159799 | Toms River | New Jersey | 08755 | — |
| Ocean Rheumatology, PA /ID# 163898 | Toms River | New Jersey | 08755 | — |
| Arthritis and Osteo Assoc /ID# 159994 | Las Cruces | New Mexico | 88011 | — |
| Santa Fe Rheumatology /ID# 163783 | Santa Fe | New Mexico | 87505 | — |
| NYU Langone Rheum Assoc /ID# 159985 | Lake Success | New York | 11554 | — |
| NYU Langone Medical Center /ID# 163230 | New York | New York | 10016-6402 | — |
| St. Lawrence Health System /ID# 159848 | Potsdam | New York | 13676 | — |
| American Health Research /ID# 164354 | Charlotte | North Carolina | 28207 | — |
| DJL Clinical Research, PLLC /ID# 161390 | Charlotte | North Carolina | 28210-8508 | — |
| M3-Emerging Medical Research, LLC /ID# 161391 | Durham | North Carolina | 27704 | — |
| Physicians East, PA /ID# 159872 | Greenville | North Carolina | 27834 | — |
| Cape Fear Arthritis Care /ID# 161224 | Leland | North Carolina | 28451 | — |
| Shanahan Rheuma & Immuno /ID# 159987 | Raleigh | North Carolina | 27617 | — |
| Trinity Health Med Arts Clinic /ID# 159800 | Minot | North Dakota | 58701 | — |
| MetroHealth Medical Center /ID# 159888 | Cleveland | Ohio | 44109 | — |
| The Ohio State University /ID# 159892 | Columbus | Ohio | 43210 | — |
| Clinical Research Source, Inc. /ID# 164545 | Perrysburg | Ohio | 43551 | — |
| STAT Research, Inc. /ID# 161392 | Vandalia | Ohio | 45377-9464 | — |
| Health Research of Oklahoma /ID# 159880 | Oklahoma City | Oklahoma | 73103-2400 | — |
| Altoona Ctr Clinical Res /ID# 159852 | Duncansville | Pennsylvania | 16635 | — |
| PA Regional Center /ID# 165670 | Wyomissing | Pennsylvania | 19610 | — |
| Articularis Healthcare Group, Inc d/b/a Low Country Rheumatology /ID# 163464 | Summerville | South Carolina | 29486-7887 | — |
| West Tennessee Research Inst /ID# 159871 | Jackson | Tennessee | 38305 | — |
| Rheumatology Consultants, PLLC /ID# 159796 | Knoxville | Tennessee | 37909 | — |
| Dr. Ramesh Gupta /ID# 160061 | Memphis | Tennessee | 38119 | — |
| Accurate Clinical Management /ID# 159905 | Baytown | Texas | 77521 | — |
| Diagnostic Group Integrated He /ID# 159794 | Beaumont | Texas | 77701 | — |
| Arth and Osteo Clin Brazo Valley /ID# 163436 | College Station | Texas | 77845 | — |
| PCCR Solution /ID# 205723 | Colleyville | Texas | 76034 | — |
| Adriana Pop-Moody MD Clinic PA /ID# 159984 | Corpus Christi | Texas | 78404 | — |
| Metroplex Clinical Research /ID# 159785 | Dallas | Texas | 75231 | — |
| Rheumatic Disease Clin Res Ctr /ID# 161240 | Houston | Texas | 77004 | — |
| Rheumatology Clinic of Houston /ID# 161234 | Houston | Texas | 77065 | — |
| "DMCR-Texas Cent for Drug Dev /ID# 164191 | Houston | Texas | 77081 | — |
| West Texas Clinical Research /ID# 205722 | Lubbock | Texas | 79410-1198 | — |
| P&I Clinical Research /ID# 159826 | Lufkin | Texas | 75904-3132 | — |
| SW Rheumatology Res. LLC /ID# 159993 | Mesquite | Texas | 75150 | — |
| Trinity Universal Research Association /ID# 205721 | Plano | Texas | 75024-5283 | — |
| Arthritis & Osteo Ctr of S. TX /ID# 163784 | San Antonio | Texas | 78232 | — |
| Arthritis Clinic of Central TX /ID# 164049 | San Marcos | Texas | 78666 | — |
| DM Clinical Research /ID# 161735 | Tomball | Texas | 77375 | — |
| Arthritis & Osteoporosis Clinic /ID# 159786 | Waco | Texas | 76710 | — |
| Arthritis Clinic of N. VA, P.C /ID# 159849 | Arlington | Virginia | 22205 | — |
| Ctr for Arth and Rheum Disease /ID# 159830 | Chesapeake | Virginia | 23320 | — |
| Swedish Medical Center /ID# 159890 | Seattle | Washington | 98104 | — |
| Arthritis Northwest, PLLC /ID# 166380 | Spokane | Washington | 99204 | — |
| West Virginia Research Inst /ID# 159791 | South Charleston | West Virginia | 25309 | — |
| Aurora Rheumatology and Immunotherapy Center /ID# 160043 | Franklin | Wisconsin | 53132 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 231 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03104400, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 21, 2025 · Synced May 20, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03104400 live on ClinicalTrials.gov.