Cobimetinib and Atezolizumab in Treating Participants With Advanced or Refractory Rare Tumors
Public ClinicalTrials.gov record NCT03108131. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II, Open-Label, Single-Arm, Multi-Cohort, Proof-of-Principle Study to Investigate the Efficacy of Cobimetinib and Atezolizumab in Advanced Rare Tumors
Study identification
- NCT ID
- NCT03108131
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- M.D. Anderson Cancer Center
- Other
- Enrollment
- 49 participants
Conditions and interventions
Conditions
- Appendix Adenocarcinoma
- Locally Advanced Malignant Neoplasm
- Locally Advanced Skin Squamous Cell Carcinoma
- Metastatic Malignant Neoplasm
- Metastatic Skin Squamous Cell Carcinoma
- Metastatic Small Intestinal Adenocarcinoma
- Rare Lesion
- Rare Neoplastic Syndrome
- Refractory Malignant Neoplasm
- Skin Squamous Cell Carcinoma
- Stage IV Small Intestinal Adenocarcinoma AJCC v8
- Unresectable Malignant Neoplasm
Interventions
- Atezolizumab Drug
- Cobimetinib Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 6, 2017
- Primary completion
- Apr 1, 2024
- Completion
- Apr 1, 2024
- Last update posted
- May 27, 2025
2017 – 2024
United States locations
- U.S. sites
- 1
- U.S. states
- 1
- U.S. cities
- 1
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| M D Anderson Cancer Center | Houston | Texas | 77030 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03108131, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 27, 2025 · Synced May 20, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03108131 live on ClinicalTrials.gov.