A Study of Crenezumab Versus Placebo to Evaluate the Efficacy and Safety in Participants With Prodromal to Mild Alzheimer's Disease (AD)
Public ClinicalTrials.gov record NCT03114657. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Efficacy and Safety Study of Crenezumab in Patients With Prodromal to Mild Alzheimer's Disease
Study identification
- NCT ID
- NCT03114657
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Hoffmann-La Roche
- Industry
- Enrollment
- 806 participants
Conditions and interventions
Conditions
Interventions
- Crenezumab Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 50 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 28, 2017
- Primary completion
- Jun 10, 2019
- Completion
- Jun 10, 2019
- Last update posted
- Jul 15, 2020
2017 – 2019
United States locations
- U.S. sites
- 48
- U.S. states
- 23
- U.S. cities
- 47
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Imaging End Points Clinical Research | Scottsdale | Arizona | 85258 | — |
| Health Initiatives Research, PLLC | Fayetteville | Arkansas | 72703 | — |
| Clinical Trials Inc. | Little Rock | Arkansas | 72205 | — |
| Neuro-Therapeutics Inc. | Pasadena | California | 91105 | — |
| Desert Valley Medical Group | Rancho Mirage | California | 92270 | — |
| Anderson Clinical Research, Inc. | Redlands | California | 92374 | — |
| University of California, Davis; Alzheimers Disease Center, Department of Neurology | Sacramento | California | 95817 | — |
| UCSF - Memory and Aging Center | San Francisco | California | 94158 | — |
| MCB Clinical Research Centers | Colorado Springs | Colorado | 80910 | — |
| Research Center for Clinical Studies, Inc. | Norwalk | Connecticut | 06851 | — |
| KI Health Partners, LLC; New England Institute for Clinical Research | Stamford | Connecticut | 06905 | — |
| Georgetown University Hospital | Washington D.C. | District of Columbia | 20057 | — |
| JEM Research LLC | Atlantis | Florida | 33462 | — |
| Bradenton Research Center | Bradenton | Florida | 34205 | — |
| Neuropsychiatric Research; Center of Southwest Florida | Fort Myers | Florida | 33912 | — |
| Alzheimer's Research and Treatment Center | Lake Worth | Florida | 33414 | — |
| Renstar Medical Research | Ocala | Florida | 34470 | — |
| Bioclinica Research | Orlando | Florida | 32806 | — |
| Progressive Medical Research | Port Orange | Florida | 32127 | — |
| Columbus Memory Center | Columbus | Georgia | 31909 | — |
| Lake Charles Clinical Trials, LLC | Lake Charles | Louisiana | 70601 | — |
| Alzheimers Disease Center; Neurology | Winchester | Massachusetts | 01890 | — |
| Health Partners Institute for Education and Research | Saint Paul | Minnesota | 55130 | — |
| Precise Research Centers | Flowood | Mississippi | 39232 | — |
| University of Nebraska Medical Center; Dept of Neurological Sciences | Omaha | Nebraska | 68198-8440 | — |
| Cleveland Clinic Lou Ruvo; Center for Brain Research | Las Vegas | Nevada | 89106 | — |
| The Cognitive and Research Center of New Jersey | Summit | New Jersey | 07081 | — |
| Advanced Memory Research Institute of NJ | Toms River | New Jersey | 08755 | — |
| Columbia University Medical Center | New York | New York | 10032 | — |
| Burke Rehabilitation Hospital | White Plains | New York | 10605 | — |
| Behavioral Health Research | Charlotte | North Carolina | 28211 | — |
| Wake Research Associates | Raleigh | North Carolina | 27612 | — |
| University of Cincinnati; Department of Psychiatry and Behavioral Neuroscience | Cincinnati | Ohio | 45219 | — |
| Ohio State University; College of Medicine | Columbus | Ohio | 43210 | — |
| Dayton Center for Neuro Disorders | Dayton | Ohio | 45459 | — |
| Summit Research Network Inc. | Portland | Oregon | 97210 | — |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | — |
| Northeastern Pennsylvania Memory | Plains | Pennsylvania | 18705 | — |
| Abington Neurological Associates | Willow Grove | Pennsylvania | 19090 | — |
| Neurology Clinic PC | Cordova | Tennessee | 38018 | — |
| Senior Adults Specialty Research | Austin | Texas | 78757 | — |
| Gadolin Research, LLC | Beaumont | Texas | 77702 | — |
| Texas Neurology PA | Dallas | Texas | 75214 | — |
| Kerwin Research Center, LLC | Dallas | Texas | 75231 | — |
| Alzheimers Disease & Memory Disorders Center; Department of Neurology Baylor College of Medicine | Houston | Texas | 77030 | — |
| Clinical Trials of Texas, Inc | San Antonio | Texas | 78229 | — |
| Sentara Medical Group | Norfolk | Virginia | 23507 | — |
| National Clinical Research Inc.-Richmond | Richmond | Virginia | 23294 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 163 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03114657, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 15, 2020 · Synced May 6, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03114657 live on ClinicalTrials.gov.