A Study to Evaluate the Efficacy and Safety of CC-220 in Subjects With Active Systemic Lupus Erythematosus
Public ClinicalTrials.gov record NCT03161483. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A PHASE 2, MULTICENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY TO EVALUATE THE EFFICACY AND SAFETY OF CC-220 IN SUBJECTS WITH ACTIVE SYSTEMIC LUPUS ERYTHEMATOSUS
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this Phase 2, multicenter, randomized, placebo-controlled, double-blind study to evaluate the efficacy and safety of an oral treatment regimen of CC-220 versus placebo in adult subjects with active systemic lupus erythematosus. Approximately 280 subjects with a documented diagnosis of SLE will be randomized 2:2:1:2 to receive CC-220 (0.45 mg QD, 0.3 mg QD or 0.15 mg QD) or identically appearing placebo.
Study identification
- NCT ID
- NCT03161483
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 289 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 31, 2017 (Actual)
- Primary completion
- Aug 3, 2021 (Actual)
- Completion
- Aug 3, 2021 (Actual)
- Last update posted
- Jun 15, 2023
2017 – 2021
United States locations
- U.S. sites
- 46
- U.S. states
- 20
- U.S. cities
- 39
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Clinical and Translational Research Center of Alabama, PC | Tuscaloosa | Alabama | 35406 | — |
| AZ Arthritis and Rheum Rsch, PLLC | Mesa | Arizona | 85202 | — |
| Saint Jude Heritage Medical Center | Fullerton | California | 92835 | — |
| University of California San Diego Medical Center | La Jolla | California | 92037 | — |
| UCLA Division of Rheumatology | Los Angeles | California | 90095 | — |
| Desert Medical Advances | Palm Desert | California | 92260 | — |
| C Michael Neuwelt M D | San Leandro | California | 94578 | — |
| Inland Rheumatology Clinical Trials | Upland | California | 91786 | — |
| University of Colorado Denver | Aurora | Colorado | 80045 | — |
| Yale University School of Medicine | New Haven | Connecticut | 06520 | — |
| Centre For Rheumatology, Immun. And Arthritis | Fort Lauderdale | Florida | 33334 | — |
| University of Florida College of Medicine | Gainesville | Florida | 32610 | — |
| University of Miami | Miami | Florida | 33136 | — |
| Integral Rheumatology and Immunology Specialists | Plantation | Florida | 33324 | — |
| Bay Care Medical Group | Tampa | Florida | 33614 | — |
| Emory University School of Medicine | Atlanta | Georgia | 30303 | — |
| Piedmont Hospital - Atlanta | Atlanta | Georgia | 30309 | — |
| Jefrey Lieberman, MD, PC | Decatur | Georgia | 30033-5910 | — |
| North Georgia Rheumatology | Lawrenceville | Georgia | 30046 | — |
| Clinic of Robert Hozman | Skokie | Illinois | 60076 | — |
| University of Maryland - School of Medicine | Baltimore | Maryland | 21201 | — |
| Beth Israel Deaconness Medical Center | Boston | Massachusetts | 02215 | — |
| Advanced Rheumatology | Lansing | Michigan | 48910 | — |
| Great Lakes Center of Rheumatology | Lansing | Michigan | 48910 | — |
| Arthritis and Osteoporosis Associates of New Mexico | Las Cruces | New Mexico | 88011-4741 | — |
| Local Institution - 134 | Great Neck | New York | 11021 | — |
| North Shore-LIJ Health System-Division of Rheumatology | Great Neck | New York | 11021 | — |
| NYU Langone Medical Center | New York | New York | 10016 | — |
| Local Institution - 124 | Syracuse | New York | 13210 | — |
| SUNY Upstate Medical University | Syracuse | New York | 13210 | — |
| Montefiore Medical Center | The Bronx | New York | 10461 | — |
| DJL Clinical Research | Charlotte | North Carolina | 28210 | — |
| Local Institution - 101 | Charlotte | North Carolina | 28210 | — |
| Shanahan Rheumatology and Immunotherapy | Raleigh | North Carolina | 27617 | — |
| MetroHealth Medical Systems | Cleveland | Ohio | 44109 | — |
| St. Anthony's Medical Center | Oklahoma City | Oklahoma | 73102 | — |
| Hershey Medical Center | Hershey | Pennsylvania | 17033-8807 | — |
| Local Institution - 136 | Hershey | Pennsylvania | 17033-8807 | — |
| University of Pennsylvania Department of Dermatology | Philadelphia | Pennsylvania | 19104 | — |
| University Of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| University of Pittsburgh UPMC Lupus Center of Excellence | Pittsburgh | Pennsylvania | 15213 | — |
| Advanced Rheumatology & Arthritis Research Center, PC | Wexford | Pennsylvania | 15090 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| UT Southwestern Medical Center | Dallas | Texas | 75390 | — |
| Pioneer Research Solutions | Houston | Texas | 77099 | — |
| Virginia Mason Medical Center | Seattle | Washington | 98101 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 138 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03161483, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 15, 2023 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03161483 live on ClinicalTrials.gov.