A Study Evaluating the Safety and Efficacy of Upadacitinib in Adults With Active Ankylosing Spondylitis
Public ClinicalTrials.gov record NCT03178487. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of Upadacitinib in Subjects With Active Ankylosing Spondylitis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the safety and efficacy of upadacitinib in participants with active ankylosing spondylitis (AS) who have had an inadequate response to at least 2 non-steroidal anti-inflammatory drugs (NSAIDs) or intolerance to or a contraindication for NSAIDs, and who are naïve to biologic disease-modifying anti-rheumatic drugs (bDMARD).
Study identification
- NCT ID
- NCT03178487
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 187 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 24, 2017 (Actual)
- Primary completion
- Jan 21, 2019 (Actual)
- Completion
- Feb 17, 2022 (Actual)
- Last update posted
- Mar 7, 2023
2017 – 2022
United States locations
- U.S. sites
- 22
- U.S. states
- 12
- U.S. cities
- 21
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arizona Arthritis & Rheumatolo /ID# 164446 | Phoenix | Arizona | 85032-9306 | — |
| AZ Arthritis and Rheumotology Research, PLLC /ID# 165705 | Phoenix | Arizona | 85032-9306 | — |
| David S. Hallegua MD /ID# 165090 | Beverly Hills | California | 90211 | — |
| Covina Arthritis Clinic /ID# 165061 | Covina | California | 91722 | — |
| St. Joseph Health System /ID# 166166 | Fullerton | California | 92835 | — |
| Global Research Foundation /ID# 165130 | Los Angeles | California | 90041 | — |
| Rheumatology Center of San Diego /ID# 166167 | San Diego | California | 92128-2549 | — |
| Colorado Arthritis Associates /ID# 164444 | Lakewood | Colorado | 80228 | — |
| Bay Area Arthritis and Osteo /ID# 165023 | Brandon | Florida | 33511 | — |
| LeJenue Research Associates /ID# 165202 | Miami | Florida | 33126 | — |
| HMD Research LLC /ID# 205172 | Orlando | Florida | 32819 | — |
| St. Lukes Clinic /ID# 165827 | Meridian | Idaho | 83642 | — |
| Clinical Investigation Specialists - Skokie /ID# 164385 | Skokie | Illinois | 60076 | — |
| Henry Ford Health System /ID# 165515 | Detroit | Michigan | 48202 | — |
| Aa Mrc Llc /Id# 165100 | Grand Blanc | Michigan | 48439 | — |
| St. Lawrence Health System /ID# 165025 | Potsdam | New York | 13676 | — |
| DJL Clinical Research, PLLC /ID# 165044 | Charlotte | North Carolina | 28210-8508 | — |
| Altoona Ctr Clinical Res /ID# 164470 | Duncansville | Pennsylvania | 16635 | — |
| Clinical Research Ctr Reading /ID# 164876 | Wyomissing | Pennsylvania | 19610 | — |
| Comprehensive Arthritis Care, a division of Comprehensive Rheumatology Care PLLC /ID# 168107 | Hendersonville | Tennessee | 37075-6213 | — |
| Diagnostic Group Integrated He /ID# 165195 | Beaumont | Texas | 77701 | — |
| Arth and Osteo Clin Brazo Valley /ID# 165194 | College Station | Texas | 77845 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 79 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03178487, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 7, 2023 · Synced Oct 30, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03178487 live on ClinicalTrials.gov.