Proton Beam or Intensity-Modulated Radiation Therapy in Preserving Brain Function in Patients With IDH Mutant Grade II or III Glioma
Public ClinicalTrials.gov record NCT03180502. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II Randomized Trial of Proton Vs. Photon Therapy (IMRT) for Cognitive Preservation in Patients With IDH Mutant, Low to Intermediate Grade Gliomas
Study identification
- NCT ID
- NCT03180502
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- NRG Oncology
- Other
- Enrollment
- 120 participants
Conditions and interventions
Conditions
Interventions
- Biospecimen Collection Procedure
- Intensity-Modulated Radiation Therapy Radiation
- Laboratory Biomarker Analysis Other
- Magnetic Resonance Imaging Procedure
- Proton Beam Radiation Therapy Radiation
- Quality-of-Life Assessment Other
- Questionnaire Administration Other
- Temozolomide Drug
Procedure · Radiation · Other + 1 more
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 22, 2018
- Primary completion
- May 31, 2026
- Completion
- May 31, 2027
- Last update posted
- May 6, 2026
2018 – 2027
United States locations
- U.S. sites
- 34
- U.S. states
- 16
- U.S. cities
- 30
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham Cancer Center | Birmingham | Alabama | 35233 | — |
| Boca Raton Regional Hospital | Boca Raton | Florida | 33486 | — |
| Miami Cancer Institute | Miami | Florida | 33176 | — |
| Emory Proton Therapy Center | Atlanta | Georgia | 30308 | — |
| Emory University Hospital Midtown | Atlanta | Georgia | 30308 | — |
| Emory University Hospital/Winship Cancer Institute | Atlanta | Georgia | 30322 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| Northwestern Medicine Cancer Center Delnor | Geneva | Illinois | 60134 | — |
| Northwestern Medicine Cancer Center Warrenville | Warrenville | Illinois | 60555 | — |
| University of Kansas Cancer Center | Kansas City | Kansas | 66160 | — |
| University of Kansas Cancer Center-Overland Park | Overland Park | Kansas | 66210 | — |
| University of Kansas Hospital-Westwood Cancer Center | Westwood | Kansas | 66205 | — |
| MaineHealth Maine Medical Center- Scarborough | Scarborough | Maine | 04074 | — |
| Maryland Proton Treatment Center | Baltimore | Maryland | 21201 | — |
| University of Maryland/Greenebaum Cancer Center | Baltimore | Maryland | 21201 | — |
| UM Upper Chesapeake Medical Center | Bel Air | Maryland | 21014 | — |
| Central Maryland Radiation Oncology in Howard County | Columbia | Maryland | 21044 | — |
| UM Baltimore Washington Medical Center/Tate Cancer Center | Glen Burnie | Maryland | 21061 | — |
| Massachusetts General Hospital Cancer Center | Boston | Massachusetts | 02114 | — |
| Mayo Clinic in Rochester | Rochester | Minnesota | 55905 | — |
| University of Kansas Cancer Center - North | Kansas City | Missouri | 64154 | — |
| University of Kansas Cancer Center - Lee's Summit | Lee's Summit | Missouri | 64064 | — |
| University of Kansas Cancer Center at North Kansas City Hospital | North Kansas City | Missouri | 64116 | — |
| Mercy Hospital Springfield | Springfield | Missouri | 65804 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Laura and Isaac Perlmutter Cancer Center at NYU Langone | New York | New York | 10016 | — |
| Case Western Reserve University | Cleveland | Ohio | 44106 | — |
| University Hospitals Parma Medical Center | Parma | Ohio | 44129 | — |
| University Hospitals Portage Medical Center | Ravenna | Ohio | 44266 | — |
| University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73104 | — |
| University of Pennsylvania/Abramson Cancer Center | Philadelphia | Pennsylvania | 19104 | — |
| M D Anderson Cancer Center | Houston | Texas | 77030 | — |
| FHCC at Northwest Hospital | Seattle | Washington | 98133 | — |
| University of Washington Medical Center - Montlake | Seattle | Washington | 98195 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03180502, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 6, 2026 · Synced May 8, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03180502 live on ClinicalTrials.gov.