ClinicalTrials.gov record
Completed Phase 3 Interventional Results available

A Trial to Assess Brexpiprazole Versus Placebo for the Treatment of Acute Manic Episodes Associated With Bipolar I Disorder

ClinicalTrials.gov ID: NCT03259555

Public ClinicalTrials.gov record NCT03259555. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 19, 2026, 8:32 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multicenter, Randomized, Double-blind Trial of Brexpiprazole Versus Placebo for the Acute Treatment of Manic Episodes, With or Without Mixed Features, Associated With Bipolar I Disorder

Study identification

NCT ID
NCT03259555
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc.
Industry
Enrollment
322 participants

Conditions and interventions

Interventions

  • Brexpiprazole Drug
  • Placebo Drug

Drug

Eligibility (public fields only)

Age range
18 Years to 65 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 13, 2017
Primary completion
Jan 1, 2019
Completion
Jan 1, 2019
Last update posted
Feb 9, 2020

2017 – 2019

United States locations

U.S. sites
29
U.S. states
12
U.S. cities
26
Facility City State ZIP Site status
Woodland International Research Group Little Rock Arkansas 72211
Woodland Research Northwest, LLC Rogers Arkansas 72758
ProScience Research Group Culver City California 90230
Collaborative Neuroscience Network, LLC Garden Grove California 92845
Behavioral Research Specialists, LLC Glendale California 91206
Pacific Research Partners, LLC Oakland California 94607
NRC Research Institute Orange California 92868
Asclepes Research Centers Panorama City California 91402
Ci Trials Riverside California 92506
Sharp Vista Hospital San Diego California 92123
Galiz Research Hialeah Florida 33016
Advanced Research Institute of Miami Homestead Florida 33030
Florida Behavioral Medicine Largo Florida 33770
Optimus U Corporation Miami Florida 33125
Behavioral Clinical Research, Inc. North Miami Florida 33161
Segal Trials North Miami Florida 33161
Radiant Research Inc. Atlanta Georgia 30325
Alexian Brothers Center for Psychiatric Research Hoffman Estates Illinois 60169
CBH Health Gaithersburg Maryland 20877
Advanced Clinical Research Center, LLC St Louis Missouri 63123
Richard H Weisler, MD, PA, and Associates Raleigh North Carolina 27609
SP Research PLLC Oklahoma City Oklahoma 73112
Cutting Edge Research Group Oklahoma City Oklahoma 73116
Carolina Clinical Trials, Inc. Charleston South Carolina 29407
University of Texas at Austin Austin Texas 78712
Community Clinical Research, Inc. Austin Texas 78754
Pillar Clinical Research, LLC Garland Texas 75042
Pillar Clinical Research, LLC Richardson Texas 75080
Mid Columbia Research Richland Washington 99352

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 19 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03259555, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 9, 2020 · Synced May 19, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03259555 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →