SYD985 vs. Physician's Choice in Participants With HER2-positive Locally Advanced or Metastatic Breast Cancer
Public ClinicalTrials.gov record NCT03262935. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multi-centre, Open-label, Randomized Clinical Trial Comparing the Efficacy and Safety of the Antibody-drug Conjugate SYD985 to Physician's Choice in Patients With HER2-positive Unresectable Locally Advanced or Metastatic Breast Cancer
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to demonstrate that SYD985 \[(vic-)trastuzumab duocarmazine\] is superior to physician's choice in prolonging progression free survival.
Study identification
- NCT ID
- NCT03262935
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 437 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 15, 2017 (Actual)
- Primary completion
- Mar 31, 2021 (Actual)
- Completion
- Jun 30, 2022 (Actual)
- Last update posted
- Oct 19, 2023
2017 – 2022
United States locations
- U.S. sites
- 23
- U.S. states
- 15
- U.S. cities
- 20
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Southern Cancer Center | Mobile | Alabama | 36608 | — |
| Arizona Clinical Research Center | Tucson | Arizona | 85715 | — |
| Moores UCSD Cancer Center | San Diego | California | 92093 | — |
| Woodlands Medical Specialists | Pensacola | Florida | 32503 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| Cancer Center of Kansas | Wichita | Kansas | 67214 | — |
| University of Maryland Greenebaum Cancer Center | Baltimore | Maryland | 21144 | — |
| Greater Baltimore Medical Center | Baltimore | Maryland | 21204 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| Saint Luke's Hospital of Kansas City | Kansas City | Missouri | 64111 | — |
| FirstHealth Outpatient Cancer Center | Pinehurst | North Carolina | 28374 | — |
| Toledo Clinic Cancer Center | Toledo | Ohio | 43623 | — |
| Northwest Cancer Specialists | Portland | Oregon | 97213 | — |
| Magee-Womens Hospital of UPMS | Pittsburgh | Pennsylvania | 15213 | — |
| Texas Oncology PA (Texas Oncology-Dallas Presbyterian Hospital) | Dallas | Texas | 75231 | — |
| Texas Oncology- Baylor Charles A. Sammor | Dallas | Texas | 75246 | — |
| Texas Oncology - Denton South | Denton | Texas | 76210 | — |
| Texas Oncology-Memorial City | Houston | Texas | 77024 | — |
| Baylor College of Medicine | Houston | Texas | 77030-34011 | — |
| Texas Oncology-San Antonio Northeast | San Antonio | Texas | 78217 | — |
| Texas Oncology-Tyler | Tyler | Texas | 75702 | — |
| Virginia Cancer Specialists, PC | Fairfax | Virginia | 22031 | — |
| Virginia Oncology Associates | Norfolk | Virginia | 23502 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 67 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03262935, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 19, 2023 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03262935 live on ClinicalTrials.gov.