A Study to Evaluate the Efficacy and Safety of Semorinemab in Patients With Prodromal to Mild Alzheimer's Disease
Public ClinicalTrials.gov record NCT03289143. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Efficacy, and Safety Study of MTAU9937A in Patients With Prodromal to Mild Alzheimer's Disease
Study identification
- NCT ID
- NCT03289143
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Genentech, Inc.
- Industry
- Enrollment
- 457 participants
Conditions and interventions
Conditions
Interventions
- Placebo Drug
- Semorinemab Drug
- [18F]GTP1 Drug
Drug
Eligibility (public fields only)
- Age range
- 50 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 3, 2017
- Primary completion
- Jan 14, 2021
- Completion
- Jan 14, 2021
- Last update posted
- Mar 15, 2022
2017 – 2021
United States locations
- U.S. sites
- 43
- U.S. states
- 17
- U.S. cities
- 42
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35249 | — |
| California Clinical Trials | Glendale | California | 91206 | — |
| University of California Irvine | Irvine | California | 92697 | — |
| Pharmacology Research Inst | Newport Beach | California | 92660 | — |
| Stanford Neuroscience Health Center (SNHC) | Palo Alto | California | 94304 | — |
| Pacific Research Network - PRN | San Diego | California | 92103 | — |
| Neurological Research Inst | Santa Monica | California | 90404 | — |
| Collaborative Neuroscience Network Inc. | Torrance | California | 90502 | — |
| Invicro, a Konica Minolta company | New Haven | Connecticut | 06510 | — |
| Yale University | New Haven | Connecticut | 06510 | — |
| KI Health Partners, LLC; New England Institute for Clinical Research | Stamford | Connecticut | 06905 | — |
| Georgetown University Hospital | Washington D.C. | District of Columbia | 20057 | — |
| JEM Research LLC | Atlantis | Florida | 33462 | — |
| Bradenton Research Center | Bradenton | Florida | 34205 | — |
| Brain Matters Research, Inc. | Delray Beach | Florida | 33445 | — |
| Neuropsychiatric Research; Center of Southwest Florida | Fort Myers | Florida | 33912 | — |
| Miami Jewish Health Systems | Miami | Florida | 33137 | — |
| Collier Neurologic Specialists | Naples | Florida | 34105 | — |
| Compass Research East, LLC | Orlando | Florida | 32806 | — |
| Stedman Clinical Trials, LLC | Tampa | Florida | 33613 | — |
| Alzheimer's Research and Treatment Center | Wellington | Florida | 33414 | — |
| Premiere Research Institute | West Palm Beach | Florida | 33407 | — |
| Emory University; Global Health | Atlanta | Georgia | 30322 | — |
| Rush Alzheimer's Disease Cntr. | Chicago | Illinois | 60612 | — |
| Alexian Brothers Neuroscience Institute | Elk Grove Village | Illinois | 60007 | — |
| Southern Illinois University, School of Medicine | Springfield | Illinois | 62702 | — |
| Eastern Maine Medical Center | Bangor | Maine | 04401 | — |
| Brigham & Women's Hosp; TIMI Study Grp | Boston | Massachusetts | 02115 | — |
| Alzheimers Disease Center | Quincy | Massachusetts | 02169 | — |
| Health Partners Institute for Education and Research | Saint Paul | Minnesota | 55130 | — |
| NeuroCognitive Institute | Mount Arlington | New Jersey | 07856 | — |
| Advanced Memory Research Institute of NJ | Toms River | New Jersey | 08755 | — |
| Albany Medical College; Neurology | Albany | New York | 12208 | — |
| Empire Neurology PC; MS Center of Northeastern NY | Latham | New York | 12110 | — |
| Columbia Univ Medical Center | New York | New York | 10032 | — |
| University of Rochester; AD-CARE | Rochester | New York | 14642 | — |
| Summit Research Network Inc. | Portland | Oregon | 97210 | — |
| Abington Neurological Associates | Abington | Pennsylvania | 19001 | — |
| Rhode Island Mood & Memory Research Institute | East Providence | Rhode Island | 02914 | — |
| Butler Hospital | Providence | Rhode Island | 02906 | — |
| Neurology Clinic PC | Cordova | Tennessee | 38018 | — |
| New Orleans Center For Clinical Research | Knoxville | Tennessee | 37920 | — |
| Clinical Neuroscience Research Associates, Inc. | Bennington | Vermont | 05201 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 90 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03289143, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 15, 2022 · Synced May 12, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03289143 live on ClinicalTrials.gov.