ClinicalTrials.gov record
Active, not recruiting Phase 2 Interventional

Aggressive Smoldering Curative Approach Evaluating Novel Therapies and Transplant

ClinicalTrials.gov ID: NCT03289299

Public ClinicalTrials.gov record NCT03289299. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 10, 2026, 3:23 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Aggressive Smoldering Curative Approach Evaluating Novel Therapies (ASCENT): A Phase 2 Trial of Induction, Consolidation, and Maintenance in Subjects With High Risk Smoldering Multiple Myeloma (SMM)

Study identification

NCT ID
NCT03289299
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 2
Lead sponsor
International Myeloma Foundation
Other
Enrollment
87 participants

Conditions and interventions

Interventions

  • Carfilzomib Drug
  • Daratumumab Drug
  • Dexamethasone Drug
  • Lenalidomide Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 24, 2018
Primary completion
Sep 25, 2023
Completion
Nov 14, 2031
Last update posted
Dec 11, 2023

2018 – 2031

United States locations

U.S. sites
10
U.S. states
10
U.S. cities
10
Facility City State ZIP Site status
Moffitt Cancer Center Tampa Florida 33612
University of Chicago Medical Center Chicago Illinois 60637
Indiana University Simon Cancer Center Indianapolis Indiana 46202
University of Kansas Cancer Center Westwood Kansas 66205
University of Maryland Medical Center Baltimore Maryland 21201
Mayo Clinic Rochester Minnesota 55905
Weill Cornell Medicine New York New York 10022
Levine Cancer Institute Charlotte North Carolina 28204
Swedish Cancer Institute Seattle Washington 98104
Medical College of Wisconsin Milwaukee Wisconsin 53226

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03289299, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 11, 2023 · Synced May 10, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03289299 live on ClinicalTrials.gov.

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