Local Bisphosphonate Effect on Recurrence Rate in Extremity Giant Cell Tumor of Bone

ClinicalTrials.gov ID: NCT03295981

Public ClinicalTrials.gov record NCT03295981. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Apr 29, 2026, 1:27 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Local Bisphosphonate Effect on Recurrence Rate in Extremity Giant Cell Tumor of Bone: A Prospective Randomized Controlled Trial

Study identification

NCT ID: NCT03295981
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 3
Lead sponsor: St. Louis University; Other
Enrollment: 120 participants

Conditions and interventions

Conditions

Giant Cell Tumor of Bone

Interventions

Zoledronic Acid Drug

Drug

Eligibility (public fields only)

Age range: 18 Years and older
Sex: All
Healthy volunteers: Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: May 2, 2018
Primary completion: Dec 31, 2026
Completion: Dec 31, 2027
Last update posted: Apr 21, 2026

2018 – 2028

United States locations

U.S. sites: 14
U.S. states: 12
U.S. cities: 12

Facility	City	State	ZIP	Site status
University of California - Los Angeles	Los Angeles	California	90404	Recruiting
Indiana University	Indianapolis	Indiana	46202	Recruiting
University of Iowa	Iowa City	Iowa	52242	Recruiting
University of Kansas	Overland Park	Kansas	66211	Completed
Johns Hopkins University Hospital	Baltimore	Maryland	21287	Recruiting
Massachusetts General Hospital	Boston	Massachusetts	02114	Recruiting
Boston Children's Hospital	Boston	Massachusetts	02115	Recruiting
Beth Israel Deaconess Medical Center	Boston	Massachusetts	02215	Recruiting
Saint Louis University	St Louis	Missouri	63110	Recruiting
Wake Forest University	Winston-Salem	North Carolina	27157	Completed
Cleveland Clinic	Cleveland	Ohio	44195	Recruiting
University of Oklahoma	Oklahoma City	Oklahoma	73104	Recruiting
Allegheny-Singer Research Institute	Pittsburgh	Pennsylvania	15212	Recruiting
University of Washington	Seattle	Washington	98195	Completed

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT03295981, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Apr 21, 2026 · Synced Apr 29, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03295981 live on ClinicalTrials.gov.

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