Treatment of Graves' Orbitopathy (Thyroid Eye Disease) to Reduce Proptosis With Teprotumumab Infusions in a Randomized, Placebo-Controlled, Clinical Study
Public ClinicalTrials.gov record NCT03298867. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-Masked, Placebo-Controlled, Parallel-Group, Multicenter Study Evaluating Teprotumumab (HZN-001) Treatment in Subjects With Active Thyroid Eye Disease
Study identification
- NCT ID
- NCT03298867
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Amgen
- Industry
- Enrollment
- 83 participants
Conditions and interventions
Conditions
Interventions
- Placebo Other
- Teprotumumab Biological
Other · Biological
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 3, 2017
- Primary completion
- Feb 12, 2019
- Completion
- Nov 29, 2020
- Last update posted
- Jul 10, 2024
2017 – 2020
United States locations
- U.S. sites
- 9
- U.S. states
- 7
- U.S. cities
- 9
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Macro, Llc | Beverly Hills | California | 90212 | — |
| Cedars-Sinai Medical Center | Los Angeles | California | 90078 | — |
| The Lennar Foundation Medical | Coral Gables | Florida | 33146 | — |
| Bascom Palmer Eye Institute | Miami | Florida | 33136 | — |
| Kellogg Eye Center at University of Michigan | Ann Arbor | Michigan | 48105 | — |
| Casey Eye Institute at Oregon Health and Science University | Portland | Oregon | 97239 | — |
| Hamilton Eye Institute at University of Tennessee Health Science Center | Memphis | Tennessee | 38163 | — |
| Eye Wellness Center | Houston | Texas | 77005 | — |
| Medical College of Wisconsin, The Eye Institute | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 5 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03298867, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 10, 2024 · Synced May 17, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03298867 live on ClinicalTrials.gov.