Study to Determine the Safety and the Efficacy of Fasinumab Compared to Placebo and Nonsteroidal Anti-inflammatory Drugs (NSAIDs) for Treatment of Adults With Pain From Osteoarthritis of the Knee or Hip
Public ClinicalTrials.gov record NCT03304379. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase 3 Randomized, Double-Blind, Multi-Dose, Placebo And NSAID Controlled Study To Evaluate The Efficacy And Safety Of Fasinumab In Patients With Pain Due To Osteoarthritis Of The Knee Or Hip
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objective of the study is to evaluate the efficacy of fasinumab compared to placebo, when administered for up to 24 weeks in patients with pain due to osteoarthritis (OA) of the knee or hip. The secondary objectives of the study are: * To evaluate the efficacy of fasinumab compared to non-steroidal anti-inflammatory drugs (NSAID)s, when administered for up to 24 weeks in patients with pain due to OA of the knee or hip * To assess the safety and tolerability of fasinumab compared to placebo and compared to NSAIDs, when administered for up to 24 weeks in patients with pain due to OA of the knee or hip
Study identification
- NCT ID
- NCT03304379
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,650 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 26, 2017 (Actual)
- Primary completion
- Dec 13, 2019 (Actual)
- Completion
- Nov 9, 2020 (Actual)
- Last update posted
- Feb 24, 2023
2017 – 2020
United States locations
- U.S. sites
- 71
- U.S. states
- 27
- U.S. cities
- 66
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Pinnacle Research Group, Llc | Anniston | Alabama | 36207 | — |
| Horizon Research Partners | Mobile | Alabama | 36608 | — |
| Clinical Research Advantage, Inc./Warner Family Practice, PC | Chandler | Arizona | 85224 | — |
| Synexus Central Phoenix Medical Clinic | Phoenix | Arizona | 85020 | — |
| Clinical Research Consortium Arizona | Tempe | Arizona | 85283 | — |
| Advance Research Center | Anaheim | California | 92805 | — |
| TriWest Research Associates, LLC | El Cajon | California | 92020 | — |
| Paragon Rx Clinical Research, Inc. | Garden Grove | California | 92840 | — |
| Catalina Research Institute, LLC | Montclair | California | 91763 | — |
| Sierra Clinical Research | Roseville | California | 95661 | — |
| UC Davis Center for Musculoskeletal Health | Sacramento | California | 95817 | — |
| Advanced Research Center, Inc | San Diego | California | 92103 | — |
| California Research Foundation | San Diego | California | 92123 | — |
| Paragon Rx Clinical Research, Inc | Santa Ana | California | 92703 | — |
| Encompass Clinical Research | Spring Valley | California | 91978 | — |
| Westlake Medical Research | Thousand Oaks | California | 91360 | — |
| Synexus Clinical Research US, Inc. | Vista | California | 92083 | — |
| Mountain View Clinical Research | Denver | Colorado | 80209 | — |
| New England Research Associates, LLC | Bridgeport | Connecticut | 06606 | — |
| CRM of Greater New Haven, LLC | Hamden | Connecticut | 06157 | — |
| Stamford Therapeutics Consortium | Stamford | Connecticut | 06905 | — |
| Avail Clinical Research, LLC | DeLand | Florida | 32720 | — |
| AMB Research Center, Inc | Miami | Florida | 33144 | — |
| Allied Biomedical Research Institute | Miami | Florida | 33155 | — |
| Lakes Research, LLC | Miami Lakes | Florida | 33014 | — |
| Bioclinica Research | Orlando | Florida | 32806 | — |
| Gulf Region Clinical Research institute | Pensacola | Florida | 32514 | — |
| Integral Rheumatology & Immunology Specialists (IRIS) | Plantation | Florida | 33324 | — |
| Progressive Medical Research | Port Orange | Florida | 32127 | — |
| Drug Studies America | Marietta | Georgia | 30060 | — |
| Georgia Institute For Clinical Research LLC | Marietta | Georgia | 30060 | — |
| North Georgia Clinical Research | Woodstock | Georgia | 30189 | — |
| Chicago Clinical Research Institute, Inc | Chicago | Illinois | 60607 | — |
| Affinity Clinical Research Institute | Oak Lawn | Illinois | 60453 | — |
| Clinical Research Advantage, Inc. | Evansville | Indiana | 47714 | — |
| MediSphere Medical Research Center, LLC | Evansville | Indiana | 47714 | — |
| L-MARC Research Center | Louisville | Kentucky | 40213 | — |
| Tandem Clinical Research | Marrero | Louisiana | 70072 | — |
| Tufts Medical Center, Inc. | Boston | Massachusetts | 02111 | — |
| Great Lakes Research Group, Inc. | Bay City | Michigan | 48706 | — |
| Onyx Clinical Research | Caro | Michigan | 48723 | — |
| Synexus Clinical Research US, Inc. | Richfield | Minnesota | 55423 | — |
| Skyline Medical Center /Radiant Research, Inc. | Elkhorn | Nebraska | 68022 | — |
| Meridian Clinical Research Associates, LLC | Omaha | Nebraska | 68134 | — |
| Robert Kaplan, D.O. | Las Vegas | Nevada | 89144 | — |
| Amici Clinical Research, LLC | Raritan | New Jersey | 08869 | — |
| Albuquerque Clinical Trials, Inc. | Albuquerque | New Mexico | 87102 | — |
| Drug Trial Brooklyn | Brooklyn | New York | 11230 | — |
| Northwell Health | Great Neck | New York | 11021 | — |
| Drug Trials America | Hartsdale | New York | 10530 | — |
| Upstate Clinical Research Associates, LLC | Williamsville | New York | 14221 | — |
| Carolina Research Center | Shelby | North Carolina | 28150 | — |
| PMG Research of Wilmington LLC | Wilmington | North Carolina | 28401 | — |
| The Center For Clinical Research | Winston-Salem | North Carolina | 27103 | — |
| New Horizons Clinical Research | Cincinnati | Ohio | 45242 | — |
| Aventiv Research Inc | Columbus | Ohio | 43213 | — |
| DOC Clinical Research | Dayton | Ohio | 45432 | — |
| Center for Orthopaedics and Sports Medicine | Indiana | Pennsylvania | 15701 | — |
| Radiant Research, Inc. | Anderson | South Carolina | 29621 | — |
| Piedmont Comprehensive Pain Management Group | Greenville | South Carolina | 29601 | — |
| Radiant Research, Inc. | Greer | South Carolina | 29651 | — |
| Coastal Carolina Research Center at LowCountry Orthopaedics | North Charleston | South Carolina | 29406 | — |
| Piedmont Research Partners, LLC | Old Point Station | South Carolina | 29707 | — |
| ACME Research, LLC | Orangeburg | South Carolina | 29118 | — |
| Office of Dr.Ramesh C. Gupta MD | Memphis | Tennessee | 38119 | — |
| West Texas Clinical Research | Lubbock | Texas | 79410 | — |
| Clinical Investigations Of Texas | Plano | Texas | 75075 | — |
| Synexus USA | Plano | Texas | 75093 | — |
| Charlottesville Medical Research Center LLC | Charlottesville | Virginia | 22911 | — |
| Health Research of Hampton Roads, Inc | Newport News | Virginia | 23606 | — |
| Spokane Joint Replacement Center | Spokane | Washington | 99218 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03304379, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 24, 2023 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03304379 live on ClinicalTrials.gov.