ClinicalTrials.gov record
Completed Phase 2 Interventional

A Dose Ranging Study of OPT-302 With Ranibizumab in Neovascular (Wet) AMD

ClinicalTrials.gov ID: NCT03345082

Public ClinicalTrials.gov record NCT03345082. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 6, 2026, 8:38 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Dose-Ranging Study of Intravitreal OPT-302 in Combination With Ranibizumab, Compared With Ranibizumab Alone, in Participants With Neovascular Age-Related Macular Degeneration (Wet AMD)

Study identification

NCT ID
NCT03345082
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Opthea Limited
Industry
Enrollment
366 participants

Conditions and interventions

Interventions

  • OPT-302 Biological
  • ranibizumab Biological
  • sham intravitreal injection Other

Biological · Other

Eligibility (public fields only)

Age range
50 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 5, 2017
Primary completion
May 13, 2019
Completion
May 13, 2019
Last update posted
Jan 11, 2021

2017 – 2019

United States locations

U.S. sites
55
U.S. states
21
U.S. cities
52
Facility City State ZIP Site status
Opthea Investigational Site Phoenix Arizona 85014
Opthea Investigational Site Phoenix Arizona 85020
Opthea Investigational Site Beverly Hills California 90211
Opthea Investigational Site Encino California 91436
Opthea Investigational Site Palm Desert California 92260
Opthea Investigational Site Redlands California 92374
Opthea Study Site Sacramento California 95819
Opthea Investigational Site Sacramento California 95841
Opthea Investigational Site San Diego California 94143
Opthea Investigational Site Santa Ana California 92705
Opthea Investigational Site Santa Barbara California 93103
Opthea Investigational Site Santa Maria California 93454
Opthea Investigational Site Colorado Springs Colorado 80909
Opthea Investigational Site Golden Colorado 80401
Opthea Investigational Site Boynton Beach Florida 33426
Opthea Investigational Site Fort Myers Florida 33907
Opthea Investigational Site Fort Myers Florida 33912
Opthea Investigational Site Melbourne Florida 32901
Opthea Investigational Site Pensacola Florida 32503
Opthea Investigational Site St. Petersburg Florida 33703
Opthea Investigational Site Tallahassee Florida 32308
Opthea Investigational Site Winter Haven Florida 33880
Opthea Investigational Site Augusta Georgia 30909
Opthea Investigational Site Shawnee Mission Kansas 66204
Opthea Investigational Site Wichita Kansas 67214
Opthea Investigational Site Paducah Kentucky 42001
Opthea Investigational Site Baltimore Maryland 21204
Opthea Investigational Site Grand Rapids Michigan 49546
Opthea Investigational Site Las Vegas Nevada 89144
Opthea Investigational Site Reno Nevada 89502
Opthea Investigational Site Edison New Jersey 08820
Opthea Investigational Site Teaneck New Jersey 07666
Opthea Investigational Site Albuquerque New Mexico 87109
Opthea Investigational Site Lynbrook New York 11563
Opthea Investigational Site Rochester New York 14620
Opthea Investigational Site Syracuse New York 13224
Opthea Investigational Site Asheville North Carolina 28803
Opthea Investigational Site Charlotte North Carolina 28210
Opthea Investigational Site Cleveland Ohio 44195
Opthea Investigational Site Columbus Ohio 43212
Opthea Investigational Site Portland Oregon 97239
Opthea Investigational Site Camp Hill Pennsylvania 17011
Opthea Investigational Site Kingston Pennsylvania 18704
Opthea Investigational Site Philadelphia Pennsylvania 19107
Opthea Investigational Site Ladson South Carolina 29456
Opthea Investigational Site West Columbia South Carolina 29169
Opthea Investigational Site Abilene Texas 79606
Opthea Investigational Site Austin Texas 78705
Opthea Investigational Site Houston Texas 77030
Opthea Investigational Site San Antonio Texas 78240
Opthea Investigational Site The Woodlands Texas 77384
Opthea Investigational Site Willow Park Texas 76087
Opthea Investigational Site Fairfax Virginia 22031
Opthea Investigational Site Virginia Beach Virginia 23462
Opthea Investigational Site Silverdale Washington 98383

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 53 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03345082, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 11, 2021 · Synced May 6, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03345082 live on ClinicalTrials.gov.

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