An Investigational Immuno-therapy Study Of Nivolumab In Combination With Trametinib With Or Without Ipilimumab In Participants With Previously Treated Cancer of the Colon or Rectum That Has Spread
Public ClinicalTrials.gov record NCT03377361. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Study Of Nivolumab In Combination With Trametinib With Or Without Ipilimumab In Participants With Previously Treated Metastatic Colorectal Cancers
Study identification
- NCT ID
- NCT03377361
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Lead sponsor
- Bristol-Myers Squibb
- Industry
- Enrollment
- 325 participants
Conditions and interventions
Interventions
- Ipilimumab Biological
- Nivolumab Biological
- Regorafenib Drug
- Trametinib Drug
Biological · Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 30, 2018
- Primary completion
- Nov 3, 2024
- Completion
- Nov 3, 2024
- Last update posted
- Dec 2, 2025
2018 – 2024
United States locations
- U.S. sites
- 16
- U.S. states
- 11
- U.S. cities
- 14
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Local Institution - 0022 | Birmingham | Alabama | 35249 | — |
| Local Institution - 0027 | Los Angeles | California | 90033 | — |
| Local Institution - 0067 | Los Angeles | California | 90089 | — |
| Local Institution - 0001 | San Francisco | California | 94158 | — |
| Local Institution - 0107 | Gainesville | Florida | 32610 | — |
| Local Institution - 0111 | Miami | Florida | 33136 | — |
| Local Institution - 0028 | Baltimore | Maryland | 21287 | — |
| Local Institution - 0116 | Hattiesburg | Mississippi | 39401-7233 | — |
| Local Institution - 0103 | St Louis | Missouri | 63110 | — |
| Local Institution - 0104 | New York | New York | 10016 | — |
| Local Institution - 0029 | Charlotte | North Carolina | 28204 | — |
| Local Institution - 0100 | Lancaster | Pennsylvania | 17604 | — |
| Local Institution - 0003 | Philadelphia | Pennsylvania | 19104 | — |
| Thomas Jefferson University - Clinical Research Institute | Philadelphia | Pennsylvania | 19107 | — |
| Local Institution - 0101 | Temple | Texas | 76508 | — |
| Local Institution - 0002 | Madison | Wisconsin | 53792-0001 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 31 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03377361, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 2, 2025 · Synced May 16, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03377361 live on ClinicalTrials.gov.