Pre-operative Aqueous Antiseptic Skin Solutions in Open Fractures
Public ClinicalTrials.gov record NCT03385304. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Aqueous-PREP: A Pragmatic Randomized Trial Evaluating Pre-operative Aqueous Antiseptic Skin Solutions in Open Fractures
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The prevention of infection is the single most important goal influencing peri-operative care of patients with open fractures. Standard practice in the management of open fractures includes sterile technique and pre-operative skin preparation with an antiseptic solution. The available solutions kill bacteria and decrease the quantity of native skin flora, thereby decreasing surgical site infection (SSI). While there is extensive guidance on specific procedures for prophylactic antibiotic use and standards for sterile technique, the evidence regarding the choice of antiseptic skin preparation solution is very limited for open fracture surgery.
Study identification
- NCT ID
- NCT03385304
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- 1,638 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 7, 2018
- Primary completion
- Oct 18, 2021
- Completion
- Jun 26, 2022
- Last update posted
- Mar 30, 2023
2018 – 2022
United States locations
- U.S. sites
- 11
- U.S. states
- 9
- U.S. cities
- 11
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| The CORE Institute / Banner University Medical Center | Phoenix | Arizona | 85006 | — |
| Banner - University Medical Center Tucson | Tucson | Arizona | 85721 | — |
| University of California San Francisco | San Francisco | California | 94143 | — |
| University of Florida | Gainesville | Florida | 32611 | — |
| Indiana University Health Methodist Hospital | Indianapolis | Indiana | 46202 | — |
| University of Maryland, R Adams Cowley Shock Trauma Center | Baltimore | Maryland | 21201 | — |
| Wright State University / Miami Valley Hospital | Dayton | Ohio | 45409 | — |
| Greenville Health System | Greenville | South Carolina | 29605 | — |
| Vanderbilt University | Nashville | Tennessee | 37240 | — |
| San Antonio Military Medical Center | Fort Sam Houston | Texas | 78234 | — |
| McGovern Medical School at University of Texas Health Science Center Houston | Houston | Texas | 77030 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 4 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03385304, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 30, 2023 · Synced Sep 8, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03385304 live on ClinicalTrials.gov.