Study of IMNN-001 (Also Known as GEN-1) With NACT for Treatment of Ovarian Cancer (OVATION 2)
Public ClinicalTrials.gov record NCT03393884. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase I/II Study Evaluating the Dosing, Safety, Efficacy, and Biological Activity of Intraperitoneal IMNN-001 (IL-12 Plasmid Formulated With PEG-PEI-Cholesterol Lipopolymer) Administered in Combination With Neoadjuvant Chemotherapy (NACT) in Patients Newly Diagnosed With Advanced Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a randomized, open label, multicenter trial to evaluate the safety, dosing, efficacy and biological activity of intraperitoneal IMNN-001 plus NACT compared to NACT alone.
Study identification
- NCT ID
- NCT03393884
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Enrollment
- 130 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 5, 2018 (Actual)
- Primary completion
- Jul 25, 2024 (Actual)
- Completion
- May 30, 2026 (Estimated)
- Last update posted
- May 4, 2026
2018 – 2026
United States locations
- U.S. sites
- 20
- U.S. states
- 13
- U.S. cities
- 20
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama Birmingham | Birmingham | Alabama | 35233 | — |
| Mitchell Cancer Institute (University of South Alabama) | Mobile | Alabama | 36604 | — |
| Gynecologic Oncology Associates (Hoag Hospital) | Newport Beach | California | 92663 | — |
| Innovative Clinical Research | Whittier | California | 90603 | — |
| Advent Health | Orlando | Florida | 32803 | — |
| Women's Care Florida | St. Petersburg | Florida | 33701 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Washington University School of Medicine in St. Louis | St Louis | Missouri | 63110 | — |
| MD Anderson at Cooper | Camden | New Jersey | 08105 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| Monter Cancer Center | Lake Success | New York | 11042 | — |
| NYU Langone, Long Island | Mineola | New York | 11501 | — |
| NYU Langone | New York | New York | 10016 | — |
| Stephenson Cancer Center - Oklahoma University | Oklahoma City | Oklahoma | 73104 | — |
| Providence Cancer Institute | Portland | Oregon | 97213 | — |
| Sanford Health | Sioux Falls | South Dakota | 57104 | — |
| Chattanooga Women's Health | Chattanooga | Tennessee | 37403 | — |
| The West Clinic | Germantown | Tennessee | 38138 | — |
| Providence Health Care | Spokane | Washington | 99204 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03393884, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 4, 2026 · Synced Oct 26, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03393884 live on ClinicalTrials.gov.