A Phase 3 STudy of CaPRe In LOwering Very hiGh TriglYcerides (TRILOGY 1)
Public ClinicalTrials.gov record NCT03398005. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Multi-center, Placebo-controlled, Randomized, Double-blind 26-week Study to Assess the Safety and Efficacy of CaPre® in Patients With Severe Hypertriglyceridemia.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objective of this study is to determine the efficacy of CaPre 4 g daily, compared to placebo, in lowering fasting triglyceride (TG) levels in patients with fasting TG levels ≥500 mg/dL and ≤1500 mg/dL (≥5.7 mmol/L and ≤17.0 mmol/L) after 12 weeks of treatment. Approximately 615 subjects will be screened to obtain 245 randomized subjects following a 2.5:1 treatment allocation ratio (CaPre: placebo).
Study identification
- NCT ID
- NCT03398005
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 256 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 23, 2018 (Actual)
- Primary completion
- Jul 21, 2019 (Actual)
- Completion
- Nov 20, 2019 (Actual)
- Last update posted
- Jan 18, 2020
2018 – 2019
United States locations
- U.S. sites
- 69
- U.S. states
- 26
- U.S. cities
- 60
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research site | Birmingham | Alabama | 35242 | — |
| Research site | Tucson | Arizona | 85712 | — |
| Research site | Conway | Arkansas | 72034 | — |
| Research site | El Cajon | California | 92020 | — |
| Research site | Fresno | California | 93702 | — |
| Research site | Garden Grove | California | 92844 | — |
| Research site | Lomita | California | 90717 | — |
| Research site | Newport Beach | California | 92663 | — |
| Research site | Tustin | California | 92780 | — |
| Research site | Boca Raton | Florida | 33487 | — |
| Research site | Clearwater | Florida | 33765 | — |
| Research site | Fort Myers | Florida | 33912 | — |
| Research site | Hialeah | Florida | 33012 | — |
| Research site | Homestead | Florida | 33030 | — |
| Research site | Jacksonville | Florida | 32256 | — |
| Research site | Kendall | Florida | 33175 | — |
| Research site | Lake Worth | Florida | 33461 | — |
| Research site | Miami | Florida | 33125 | — |
| Research site | Miami | Florida | 33126 | — |
| Research site | Miami | Florida | 33135 | — |
| Research site | Miami | Florida | 33144 | — |
| Research site | Miami | Florida | 33155 | — |
| Research site | Miami | Florida | 33165 | — |
| Research site | Miami | Florida | 33173 | — |
| Research site | Miami Springs | Florida | 33166 | — |
| Research site | North Miami Beach | Florida | 33162 | — |
| Research site | Orlando | Florida | 32825 | — |
| Research site | Pembroke Pines | Florida | 33026 | — |
| Research site | Tamarac | Florida | 33321 | — |
| Research site | Tampa | Florida | 33603 | — |
| Research site | Wellington | Florida | 33449 | — |
| Research site | West Palm Beach | Florida | 33401 | — |
| Research site | West Palm Beach | Florida | 33409 | — |
| Research site | Atlanta | Georgia | 30345 | — |
| Research site | Gainesville | Georgia | 30501 | — |
| Research site | Savannah | Georgia | 31406 | — |
| Research site | Snellville | Georgia | 30078 | — |
| Research site | Sugar Hill | Georgia | 30518 | — |
| Research site | Meridian | Idaho | 83642 | — |
| Research site | Meridian | Idaho | 83646 | — |
| Research site | Gurnee | Illinois | 60031 | — |
| Research site | Anderson | Indiana | 46011 | — |
| Research site | Louisville | Kentucky | 40213 | — |
| Research site | Eunice | Louisiana | 70535 | — |
| Research site | Cadillac | Michigan | 49601 | — |
| Research site | Jackson | Mississippi | 39202 | — |
| Research site | Olive Branch | Mississippi | 38654 | — |
| Research site | St Louis | Missouri | 63117 | — |
| Research site | Omaha | Nebraska | 68114 | — |
| Research site | Greensboro | North Carolina | 27408 | — |
| Research site | Mooresville | North Carolina | 28117 | — |
| Research site | Canton | Ohio | 44710 | — |
| Research site | Marion | Ohio | 43302 | — |
| Research site | Maumee | Ohio | 43537 | — |
| Research site | Norman | Oklahoma | 73069 | — |
| Research site | Beaver | Pennsylvania | 15009 | — |
| Research site | Spartanburg | South Carolina | 29301 | — |
| Research site | Chattanooga | Tennessee | 37421 | — |
| Research site | Memphis | Tennessee | 38119 | — |
| Research site | Arlington | Texas | 76012 | — |
| Research site | Houston | Texas | 77084 | — |
| Research site | Houston | Texas | 77089 | — |
| Research site | Lampasas | Texas | 76550 | — |
| Research site | San Antonio | Texas | 78258 | — |
| Research site | Salt Lake City | Utah | 84107 | — |
| Research site | West Jordan | Utah | 84088 | — |
| Research site | Danville | Virginia | 24541 | — |
| Research site | Bellevue | Washington | 98007 | — |
| Research site | Kenosha | Wisconsin | 53144 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03398005, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 18, 2020 · Synced Oct 31, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03398005 live on ClinicalTrials.gov.