Safety and Efficacy of IONIS-FB-Lrx in up to 120 Patients 55 and Older With Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (AMD)
Public ClinicalTrials.gov record NCT03446144. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Placebo-Controlled, Double-Masked Study to Assess Safety and Efficacy of ISIS 696844, an Antisense Inhibitor of Complement Factor B, in Patients With Geographic Atrophy Secondary (GA) to Age-Related Macular Degeneration (AMD)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to assess the Safety and Efficacy of IONIS-FB-Lrx for up to 120 patients with Geographic Atrophy secondary to Age Related Macular Degeneration
Study identification
- NCT ID
- NCT03446144
- Recruitment status
- Withdrawn
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- Not listed
Conditions and interventions
Eligibility (public fields only)
- Age range
- 55 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 16, 2018 (Actual)
- Primary completion
- Oct 10, 2018 (Actual)
- Completion
- Oct 10, 2018 (Actual)
- Last update posted
- Aug 13, 2019
2018
United States locations
- U.S. sites
- 24
- U.S. states
- 11
- U.S. cities
- 23
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| IONIS Investigative Site | Phoenix | Arizona | 85014-2709 | — |
| IONIS Investigational Site | Beverly Hills | California | 90211 | — |
| IONIS Investigative Site | Encino | California | 91436 | — |
| IONIS Investigative Site | Irvine | California | 92697 | — |
| IONIS Investigational Site | Mountain View | California | 94040 | — |
| IONIS Investigational Site | Santa Barbara | California | 93103 | — |
| IONIS Investigative Site | Clearwater | Florida | 33761 | — |
| IONIS Investigational Site | Tampa | Florida | 33612 | — |
| IONIS Investigational Site | Augusta | Georgia | 30909 | — |
| IONIS Investigational Site | Leawood | Kansas | 66211 | — |
| IONIS Investigative Site | Chesterfield | Missouri | 63017 | — |
| IONIS Investigative Site | New York | New York | 10021 | — |
| IONIS Investigative Site | Philadelphia | Pennsylvania | 19104 | — |
| IONIS Investigative Site | Philadelphia | Pennsylvania | 19107-5109 | — |
| IONIS Investigative Site | Pittsburgh | Pennsylvania | 15213 | — |
| IONIS Investigational Site | Ladson | South Carolina | 29456 | — |
| IONIS Investigative Site | Rapid City | South Dakota | 57701-7374 | — |
| IONIS Investigative Site | Arlington | Texas | 76012-2505 | — |
| IONIS Investigational Site | Austin | Texas | 78705 | — |
| IONIS Investigative Site | Dallas | Texas | 75231-5078 | — |
| IONIS Investigative Site | Houston | Texas | 77030-2727 | — |
| IONIS Investigative Site | McAllen | Texas | 78503-1518 | — |
| IONIS Investigative Site | San Antonio | Texas | 78240-1502 | — |
| IONIS Investigative Site | The Woodlands | Texas | 77384-8018 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 13 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03446144, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 13, 2019 · Synced Oct 25, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03446144 live on ClinicalTrials.gov.