ClinicalTrials.gov record
A Study of Mevrometostat for Treatment of Relapsed/Refractory SCLC, Castration Resistant Prostate Cancer, and Follicular Lymphoma
ClinicalTrials.gov ID: NCT03460977
Public ClinicalTrials.gov record NCT03460977. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 6, 2026, 7:33 PM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A PHASE I DOSE ESCALATION AND EXPANDED COHORT STUDY OF PF 06821497 (MEVROMETOSTAT) IN THE TREATMENT OF ADULT PATIENTS WITH RELAPSED/REFRACTORY SMALL CELL LUNG CANCER (SCLC), CASTRATION RESISTANT PROSTATE CANCER (CRPC) AND FOLLICULAR LYMPHOMA (FL)
Study identification
- NCT ID
- NCT03460977
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- Pfizer
- Industry
- Enrollment
- 453 participants
Conditions and interventions
Conditions
Interventions
- Enzalutamide Drug
- Itraconazole Drug
- Mervometostat (PF-06821497) Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 16, 2018
- Primary completion
- Apr 19, 2028
- Completion
- Jul 6, 2029
- Last update posted
- May 4, 2026
2018 – 2029
United States locations
- U.S. sites
- 45
- U.S. states
- 15
- U.S. cities
- 25
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Banner-University Medical Center Tucson | Tucson | Arizona | 85719 | Active, not recruiting |
| The University of Arizona Cancer Center-North Campus | Tucson | Arizona | 85719 | Active, not recruiting |
| The University of Arizona Cancer Center | Tucson | Arizona | 85724 | Active, not recruiting |
| Arizona Urology Specialists, PLLC | Tucson | Arizona | 85741 | Terminated |
| Pacific Cancer Medical Center INC | Anaheim | California | 92801 | Active, not recruiting |
| City of Hope (City of Hope National Medical Center, City of Hope Medical Center) | Duarte | California | 91010 | Active, not recruiting |
| City of Hope Investigational Drug Services (IDS) | Duarte | California | 91010 | Active, not recruiting |
| Norwalk Hospital | Norwalk | Connecticut | 06856 | Active, not recruiting |
| The University of Kansas Cancer Center, Investigational Drug Services | Fairway | Kansas | 66205 | Active, not recruiting |
| The University of Kansas Clinical Research Center | Fairway | Kansas | 66205 | Active, not recruiting |
| The University of Kansas Hospital | Kansas City | Kansas | 66160 | Active, not recruiting |
| The University of Kansas Medical Center Medical Office Building | Kansas City | Kansas | 66160 | Active, not recruiting |
| The University of Kansas Cancer Center - Indian Creek Campus | Overland Park | Kansas | 66211 | Active, not recruiting |
| The University of Kansas Cancer Center | Westwood | Kansas | 66205 | Active, not recruiting |
| Norton Cancer Institute Pharmacy, Downtown Pharmacy | Louisville | Kentucky | 40202 | Active, not recruiting |
| Norton Cancer Institute Pharmacy | Louisville | Kentucky | 40202 | Active, not recruiting |
| Norton Cancer Institute, Norton Healthcare Pavilion | Louisville | Kentucky | 40202 | Active, not recruiting |
| Norton Hospital | Louisville | Kentucky | 40202 | Active, not recruiting |
| Maryland Oncology Hematology, P.A. | Rockville | Maryland | 20850 | Terminated |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | Active, not recruiting |
| Dana Farber Cancer Institute | Boston | Massachusetts | 02215 | Active, not recruiting |
| Dana Farber Cancer Institute- Chestnut Hill | Newton | Massachusetts | 02459 | Active, not recruiting |
| Oncology Hematology West, PC dba Nebraska Cancer Specialists | Omaha | Nebraska | 68130 | Recruiting |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | Active, not recruiting |
| John Theurer Cancer Center at Hackensack University Medical Center | Hackensack | New Jersey | 07601 | Active, not recruiting |
| OU Health University of Oklahoma Medical Center | Oklahoma City | Oklahoma | 73104 | Recruiting |
| Stephenson Cancer Center (chemo location) | Oklahoma City | Oklahoma | 73104 | Recruiting |
| Carolina Urologic Research Center | Myrtle Beach | South Carolina | 29572 | Recruiting |
| Parkway Surgery Center | Myrtle Beach | South Carolina | 29572 | Recruiting |
| Sarah Cannon Research Institute - Pharmacy | Nashville | Tennessee | 37203 | Recruiting |
| SCRI Oncology Partners | Nashville | Tennessee | 37203 | Recruiting |
| Texas Oncology - Austin Midtown | Austin | Texas | 78705 | Terminated |
| University of Texas Southwestern Medical Center - Simmons Cancer Center | Dallas | Texas | 75390 | Active, not recruiting |
| UT Southwestern Medical Center | Dallas | Texas | 75390 | Active, not recruiting |
| UT Southwestern University Hospital - William P. Clements, Jr | Dallas | Texas | 75390 | Active, not recruiting |
| UT Southwestern University Hospital - Zale Lipshy | Dallas | Texas | 75390 | Active, not recruiting |
| US Oncology Investigational Product Center (IPC) | Irving | Texas | 75063 | Terminated |
| US Oncology Investigational Products Center | Irving | Texas | 75063 | Terminated |
| NEXT Oncology | San Antonio | Texas | 78229 | Not yet recruiting |
| NEXT Oncology | San Antonio | Texas | 78240 | Active, not recruiting |
| Virginia Cancer Specialists, PC | Fairfax | Virginia | 22031 | Active, not recruiting |
| Olympic Medical Center | Port Angeles | Washington | 98362 | Recruiting |
| Fred Hutchinson Cancer Center Alliance Peninsula | Poulsbo | Washington | 98370 | Recruiting |
| Fred Hutchinson Cancer Center | Seattle | Washington | 98109 | Recruiting |
| University of Washington Medical Center | Seattle | Washington | 98109 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 37 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03460977, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 4, 2026 · Synced May 6, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03460977 live on ClinicalTrials.gov.