Study of the Intravitreal Plasma Kallikrein Inhibitor, KVD001, in Subjects With Center-involving Diabetic Macular Edema (ciDME)
Public ClinicalTrials.gov record NCT03466099. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized Sham-controlled Double-masked Phase 2a Study of the Efficacy, Safety and Tolerability of the Intravitreal Plasma Kallikrein Inhibitor, KVD001, in Subjects With Center-involving Diabetic Macular Edema Who Have Had Prior Anti-vascular Endothelial Growth Factor Treatment
Study identification
- NCT ID
- NCT03466099
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- KalVista Pharmaceuticals, Ltd.
- Industry
- Enrollment
- 129 participants
Conditions and interventions
Conditions
Interventions
- KVD001 Injection Drug
- Sham Procedure Other
Drug · Other
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 15, 2018
- Primary completion
- Oct 9, 2019
- Completion
- Oct 9, 2019
- Last update posted
- Jan 27, 2021
2018 – 2019
United States locations
- U.S. sites
- 35
- U.S. states
- 14
- U.S. cities
- 31
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| KalVista Investigative Site | Phoenix | Arizona | 85021 | — |
| KalVista Investigative Site | Phoenix | Arizona | 85053 | — |
| KalVista Investigative Site | Tucson | Arizona | 85704 | — |
| KalVista Investigative Site | Arcadia | California | 91007 | — |
| KalVista Investigative Site | Beverly Hills | California | 90211 | — |
| KalVista Investigative Site | Palm Desert | California | 92260 | — |
| KalVista Investigative Site | Palo Alto | California | 94303 | — |
| KalVista Investigative Site | Sacramento | California | 95819 | — |
| KalVista Investigative Site | Santa Ana | California | 92705 | — |
| KalVista Investigative Site | Tustin | California | 92780 | — |
| KalVista Investigative Site | Golden | Colorado | 80401 | — |
| KalVista Investigative Site | Fort Myers | Florida | 33912 | — |
| KalVista Investigative Site | Miami | Florida | 33126 | — |
| KalVista Investigative Site | Miami | Florida | 33143 | — |
| KalVista Investigative Site | Pensacola | Florida | 32503 | — |
| KalVista Investigative Site | Winter Haven | Florida | 33880 | — |
| KalVista Investigative Site | Augusta | Georgia | 30909 | — |
| KalVista Investigative Site | Marietta | Georgia | 30060 | — |
| KalVista Investigative Site | Indianapolis | Indiana | 46290 | — |
| KalVista Investigative Site | Boston | Massachusetts | 02114 | — |
| KalVista Investigative Site | Boston | Massachusetts | 02215 | — |
| KalVista Investigative Site | Henderson | Nevada | 89052 | — |
| KalVista Investigative Site | Lynbrook | New York | 11563 | — |
| KalVista Investigative Site | Rochester | New York | 14459 | — |
| KalVista Investigative Site | Cincinnati | Ohio | 45219 | — |
| KalVista Investigative Site | Rapid City | South Dakota | 57701 | — |
| KalVista Investigative Site | Abilene | Texas | 79606 | — |
| KalVista Investigative Site | Arlington | Texas | 76012 | — |
| KalVIsta Investigative Site | Austin | Texas | 78705 | — |
| KalVista Investigative Site | Dallas | Texas | 75231 | — |
| KalVista Investigative Site | Fort Worth | Texas | 76102 | — |
| KalVista Investigative Site | San Antonio | Texas | 78240-1502 | — |
| KalVista Investigative Site | San Antonio | Texas | 78240 | — |
| KalVista Investigative Site | Charlottesville | Virginia | 22903 | — |
| KalVista Investigative Site | Silverdale | Washington | 98383 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03466099, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 27, 2021 · Synced May 20, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03466099 live on ClinicalTrials.gov.