PeriOperative ISchemic Evaluation-3 Trial
Public ClinicalTrials.gov record NCT03505723. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Study identification
- NCT ID
- NCT03505723
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Population Health Research Institute
- Other
- Enrollment
- 9,535 participants
Conditions and interventions
Interventions
- Perioperative hypertension-avoidance strategy Other
- Perioperative hypotension-avoidance strategy Other
- Placebo (Saline) Drug
- Tranexamic Acid Drug
Other · Drug
Eligibility (public fields only)
- Age range
- 45 Years and older
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 26, 2018
- Primary completion
- Nov 7, 2021
- Completion
- Feb 2, 2023
- Last update posted
- Feb 11, 2025
2018 – 2023
United States locations
- U.S. sites
- 12
- U.S. states
- 8
- U.S. cities
- 11
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Yale New Haven Hospital | New Haven | Connecticut | 06510 | — |
| Cleveland Clinic, Florida | Weston | Florida | 33331 | — |
| Columbia University | New York | New York | 10027 | — |
| University of North Carolina at Chapel Hill | Chapel Hill | North Carolina | 27599-7010 | — |
| Wake Forest | Winston-Salem | North Carolina | 27157 | — |
| Cleveland Clinic - Fairview | Cleveland | Ohio | 44111 | — |
| Cleveland Clinic - Main Campus | Cleveland | Ohio | 44195 | — |
| The Ohio State University Wexner Medical Center | Columbus | Ohio | 43210 | — |
| Cleveland Clinic - Hillcrest | Mayfield Heights | Ohio | 44124 | — |
| Oregon Health & Science University | Portland | Oregon | 97239 | — |
| Rhode Island Hospital | Providence | Rhode Island | 02903 | — |
| MD Anderson Cancer Center | Houston | Texas | 77030 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 102 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03505723, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 11, 2025 · Synced May 5, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03505723 live on ClinicalTrials.gov.