ExCEED: CENTERA THV System in Intermediate Risk Patients Who Have Symptomatic, Severe, Calcific, Aortic Stenosis
Public ClinicalTrials.gov record NCT03517436. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Prospective, Single-arm, Controlled, Multicenter Study to Establish the Safety and Effectiveness of the CENTERA THV System in Intermediate Risk Patients Who Have Symptomatic, Severe, Calcific, Aortic Stenosis Requiring Aortic Valve Replacement
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will monitor the safety and valve performance of the Edwards CENTERA Transcatheter Heart Valve (THV) System in patients with symptomatic, severe, calcific aortic stenosis who are at intermediate operative risk for surgical aortic valve replacement (SAVR).
Study identification
- NCT ID
- NCT03517436
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 101 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- Not listed
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 18, 2018 (Actual)
- Primary completion
- Oct 2, 2020 (Actual)
- Completion
- Jul 2030 (Estimated)
- Last update posted
- Nov 13, 2025
2018 – 2030
United States locations
- U.S. sites
- 23
- U.S. states
- 16
- U.S. cities
- 22
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Cedars-Sinai Medical Center | Los Angeles | California | 90048 | — |
| Stanford University Medical Center | Stanford | California | 94305 | — |
| UC Health Northern Colorado (Medical Center of the Rockies) | Loveland | Colorado | 80538 | — |
| Washington Hospital Center | Washington D.C. | District of Columbia | 20010 | — |
| Sarasota Memorial Hospital | Sarasota | Florida | 34239 | — |
| Emory University | Atlanta | Georgia | 30308 | — |
| St. Vincent Medical Group, Inc./St. Vincent Heart Center of Indiana, LLC | Indianapolis | Indiana | 46290 | — |
| University of Kansas Health System | Kansas City | Kansas | 66160 | — |
| Cardiovascular Research Institute of Kansas | Wichita | Kansas | 67226 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| Washington University/ Barnes-Jewish Hospital | St Louis | Missouri | 63110 | — |
| Atlantic Health System Hospital Corp | Morristown | New Jersey | 07960 | — |
| Columbia University Medical Center/ NYPH | New York | New York | 10032 | — |
| The Ohio Health Research Institute | Columbus | Ohio | 43214 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Allegheny - Singer Research Institute | Pittsburgh | Pennsylvania | 15212 | — |
| Saint Thomas Health | Nashville | Tennessee | 37205 | — |
| Baylor Heart and Vascular Hospital | Dallas | Texas | 75226 | — |
| The University of Texas Health Science Center at Houston | Houston | Texas | 77030 | — |
| University of Texas Memorial Hermann | Houston | Texas | 77030 | — |
| The Heart Hospital Baylor Plano | Plano | Texas | 75093 | — |
| Baylor Scott and White, Central Texas | Temple | Texas | 76508 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03517436, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 13, 2025 · Synced Oct 30, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03517436 live on ClinicalTrials.gov.