A Study to Evaluate the Long-Term Efficacy and Safety of Mirikizumab in Participants With Moderately to Severely Active Ulcerative Colitis (LUCENT 3)
Public ClinicalTrials.gov record NCT03519945. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Multicenter, Open-Label Extension Study to Evaluate the Long Term Efficacy and Safety of Mirikizumab in Patients With Moderately to Severely Active Ulcerative Colitis LUCENT 3
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study is designed to evaluate the long-term efficacy and safety of mirikizumab in participants with moderately to severely active ulcerative colitis (UC). The study will last up to 3 years. Participants who complete the 3-year study may continue to receive mirikizumab until it is (outside of this study) in their country or until they meet other discontinuation criteria.
Study identification
- NCT ID
- NCT03519945
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,058 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 18, 2018 (Actual)
- Primary completion
- Mar 4, 2026 (Actual)
- Completion
- Dec 2027 (Estimated)
- Last update posted
- Apr 20, 2026
2018 – 2027
United States locations
- U.S. sites
- 48
- U.S. states
- 22
- U.S. cities
- 44
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Digestive Health Specialists | Dothan | Alabama | 36305 | — |
| Research Solutions of Arizona | Litchfield Park | Arizona | 85340 | — |
| Valleywise Health Medical Center | Phoenix | Arizona | 85008 | — |
| InSite Digestive Health Care | Arcadia | California | 91006 | — |
| Care Access - Berkeley | Berkeley | California | 94705 | — |
| Om Research LLC | Lancaster | California | 93534 | — |
| California Medical Research Associates | Northridge | California | 91324 | — |
| Inland Empire Clinical Trials, LLC | Rialto | California | 92377 | — |
| Clinical Applications Laboratories, Inc. | San Diego | California | 92103 | — |
| Direct Helpers Research Center | Hialeah | Florida | 33012 | — |
| Encore Borland-Groover Clinical Research | Jacksonville | Florida | 32256 | — |
| Wellness Clinical Research | Miami Lakes | Florida | 33016 | — |
| AdventHealth Orlando | Orlando | Florida | 32803 | — |
| Clintheory Healthcare | Orlando | Florida | 32819 | — |
| Gastroenterology Associates of Pensacola, PA | Pensacola | Florida | 32503 | — |
| Florida Medical Clinic LLC | Zephyrhills | Florida | 33542-7505 | — |
| Digestive Healthcare of Georgia | Atlanta | Georgia | 30327 | — |
| Grand Teton Research Group | Idaho Falls | Idaho | 83404 | — |
| NorthShore University HealthSystem - Evanston Hospital | Evanston | Illinois | 60201 | — |
| Indiana University Health University Hospital | Indianapolis | Indiana | 46202 | — |
| Cotton O'Neil Digestive Health Center | Topeka | Kansas | 66606 | — |
| GI Alliance Research Baton Rouge | Baton Rouge | Louisiana | 70809 | — |
| Delta Research Partners | Monroe | Louisiana | 71201 | — |
| Nola Research Works, LLC | New Orleans | Louisiana | 70125 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| Clinical Research Institute of Michigan, LLC | Chesterfield | Michigan | 48047 | — |
| Henry Ford Medical Center - Columbus Center | Novi | Michigan | 48377 | — |
| West Michigan Clinical Research Center | Wyoming | Michigan | 49519 | — |
| MNGI Digestive Health - Plymouth Endoscopy Center & Clinic | Plymouth | Minnesota | 55446 | — |
| Columbia University Medical Center | New York | New York | 10032 | — |
| Clinical & Translational Research Center (CTRC) | Chapel Hill | North Carolina | 27599-7080 | — |
| Carolina Digestive Diseases and Endoscopy Center | Greenville | North Carolina | 27834 | — |
| Care Access - Youngstown | Poland | Ohio | 44514 | — |
| The University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73104-5008 | — |
| Central Sooner Research - Oklahoma - Northwest 47th Street | Oklahoma City | Oklahoma | 73118 | — |
| Care Access - Pottsville | Pottsville | Pennsylvania | 17901 | — |
| Digestive Disease Associates | Wyomissing | Pennsylvania | 19610 | — |
| Midwest Medical Care | Sioux Falls | South Dakota | 57108 | — |
| GI Alliance | Garland | Texas | 75044 | — |
| Biopharma Informatic, LLC | Houston | Texas | 77084 | — |
| Gastroenterology Research of San Antonio | San Antonio | Texas | 78229 | — |
| Southern Star Research Institute | San Antonio | Texas | 78229 | — |
| GI Alliance | Southlake | Texas | 76092 | — |
| Texas Digestive Disease Consultants | Southlake | Texas | 76092 | — |
| Care Access-Ogden | Ogden | Utah | 84403 | — |
| Care Access Research LLC - Salt Lake City | Salt Lake City | Utah | 84124 | — |
| Carilion Clinic | Roanoke | Virginia | 24014 | — |
| Washington Gastroenterology - Tacoma | Tacoma | Washington | 98405 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 304 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03519945, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 20, 2026 · Synced Oct 24, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03519945 live on ClinicalTrials.gov.