A Phase 3, Randomized, Double-blind, Placebo-controlled Study For Subjects With Locally-advanced Unresectable or Metastatic Synovial Sarcoma (V943-003, IMDZ-04-1702)
Public ClinicalTrials.gov record NCT03520959. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-blind, Placebo-controlled Study to Determine the Efficacy and Safety of CMB305 in Unresectable Locally-advanced or Metastatic NY-ESO-1+ Synovial Sarcoma Participants Following First Line Systemic Anti-cancer Therapy (V943-003, IMDZ-04-1702)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
To assess if the CMB305 vaccine regimen may help the body's immune system to slow or stop the growth of synovial sarcoma tumor and improve survival.
Study identification
- NCT ID
- NCT03520959
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1 participant
Conditions and interventions
Interventions
- LV305 Biological
- G305 Biological
- LV305-matching placebo Other
- G305-matching placebo Other
Biological · Other
Eligibility (public fields only)
- Age range
- 12 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 18, 2018 (Actual)
- Primary completion
- Nov 20, 2018 (Actual)
- Completion
- Nov 20, 2018 (Actual)
- Last update posted
- Apr 16, 2020
2018
United States locations
- U.S. sites
- 27
- U.S. states
- 19
- U.S. cities
- 27
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Mayo Clinic- Scottsdale | Scottsdale | Arizona | 85259 | — |
| University of Arizona Cancer Center | Tucson | Arizona | 85724 | — |
| USC Norris Comprehensive Cancer Center | Los Angeles | California | 90033 | — |
| Stanford University | Palo Alto | California | 94305 | — |
| Sarcoma Oncology Center | Santa Monica | California | 90403 | — |
| University of Colorado Cancer Center | Boulder | Colorado | 80309 | — |
| Yale University School of Medicine- Cancer Center | New Haven | Connecticut | 06520 | — |
| University of Miami | Coral Gables | Florida | 33146 | — |
| Mayo Clinic- Jacksonville | Jacksonville | Florida | 32224 | — |
| Moffitt Cancer Center at USF | Tampa | Florida | 33612 | — |
| Northwestern | Chicago | Illinois | 60611 | — |
| Dana Farber Cancer Institute/Mass General Hospital Dana-Farber Cancer Institute | Boston | Massachusetts | 02215 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| Washington University in St. Louis | St Louis | Missouri | 63110 | — |
| Nebraska Methodist Hospital | Omaha | Nebraska | 68114 | — |
| Hackensack University Medical Center | Edison | New Jersey | 08837 | — |
| Cohen Children's Medical Center (Northwell) | Astoria | New York | 11105 | — |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | — |
| Duke University | Durham | North Carolina | 27708 | — |
| Cincinnati Children's Hospital | Cincinnati | Ohio | 45229 | — |
| Ohio State University | Columbus | Ohio | 43210 | — |
| Oregon Health and Science University | Portland | Oregon | 97239 | — |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | — |
| University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | 15224 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | — |
| MD Anderson Cancer Center | Houston | Texas | 77030 | — |
| Fred Hutchinson Cancer Research Center/Seattle Cancer Care Alliance | Seattle | Washington | 98109 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03520959, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 16, 2020 · Synced Oct 26, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03520959 live on ClinicalTrials.gov.