A Study in Ovarian Cancer Patients Evaluating Rucaparib and Nivolumab as Maintenance Treatment Following Response to Front-Line Platinum-Based Chemotherapy
Public ClinicalTrials.gov record NCT03522246. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
ATHENA (A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase 3 Study in Ovarian Cancer Patients Evaluating Rucaparib and Nivolumab as Maintenance Treatment Following Response to Front-Line Platinum-Based Chemotherapy)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a Phase 3, randomized, multinational, double-blind, dual placebo-controlled, 4-arm study evaluating rucaparib and nivolumab as maintenance treatment following response to front-line treatment in newly diagnosed ovarian cancer patients. Response to treatment will be analyzed based on homologous recombination (HR) status of tumor samples.
Study identification
- NCT ID
- NCT03522246
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,097 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 14, 2018 (Actual)
- Primary completion
- May 20, 2024 (Actual)
- Completion
- Dec 30, 2030 (Estimated)
- Last update posted
- Jun 24, 2025
2018 – 2030
United States locations
- U.S. sites
- 64
- U.S. states
- 31
- U.S. cities
- 58
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arizona Oncology Associates, PC - HAL | Phoenix | Arizona | 85016 | — |
| Arizona Oncology Associates, PC - HOPE | Tucson | Arizona | 85711 | — |
| The University of Arizona Cancer Center | Tucson | Arizona | 85724 | — |
| John Muir Clinical Research Center | Concord | California | 94520 | — |
| UCLA Women's Health Clinical Research Unit | Los Angeles | California | 90095 | — |
| Kaiser Permanente Northern California | San Francisco | California | 94589 | — |
| University of Colorado Cancer Center | Aurora | Colorado | 80045 | — |
| Rocky Mountain Cancer Centers | Lakewood | Colorado | 80228 | — |
| Yale University | New Haven | Connecticut | 06520 | — |
| Florida Gynecologic Oncology | Fort Myers | Florida | 33905 | — |
| MD Anderson Cancer Center-Baptist | Jacksonville | Florida | 32207 | — |
| Baptist Health Medical Group Oncology, LLC | Miami | Florida | 33176 | — |
| Florida Hospital | Orlando | Florida | 32804 | — |
| Northside Hospital | Atlanta | Georgia | 30342 | — |
| Augusta University | Augusta | Georgia | 30912 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| Dr. Sudarshan K. Sharma, Ltd - Gynecologic Oncology | Hinsdale | Illinois | 60521 | — |
| Ferrell-Duncan Clinic | Springfield | Illinois | 62769 | — |
| Community Health Network | Indianapolis | Indiana | 46250 | — |
| University of Iowa Hospitals | Iowa City | Iowa | 52242 | — |
| University of Kansas Cancer Center | Westwood | Kansas | 66205 | — |
| University of Kentucky | Lexington | Kentucky | 40536 | — |
| Norton Cancer Institute | Louisville | Kentucky | 40241 | — |
| Ochsner Medical Center | New Orleans | Louisiana | 70121 | — |
| Maine Medical Center | Scarborough | Maine | 04074 | — |
| SKCCC at Johns Hopkins | Baltimore | Maryland | 21287 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Karmanos Cancer Institute | Detroit | Michigan | 48201 | — |
| Metro Minnesota Community Oncology Research Consortium | Saint Louis Park | Minnesota | 55416 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Women's Cancer Center of Nevada | Las Vegas | Nevada | 89169 | — |
| MD Anderson Cancer Center at Cooper | Camden | New Jersey | 08103 | — |
| Summit Medical Group | Florham Park | New Jersey | 07932 | — |
| Women's Cancer Care Associates | Albany | New York | 12008 | — |
| Broome Oncology, LLC | Johnson City | New York | 13790 | — |
| Northwell Health Monter Cancer Center | Lake Success | New York | 11042 | — |
| New York University Medical Center | New York | New York | 10016 | — |
| University of North Carolina | Chapel Hill | North Carolina | 27707 | — |
| University of Cincinnati | Cincinnati | Ohio | 45221 | — |
| Oncology Hematology Care, Inc | Cincinnati | Ohio | 45242 | — |
| Cleveland Clinic | Cleveland | Ohio | 44106 | — |
| The Ohio State University | Columbus | Ohio | 43210 | — |
| MD Anderson Cancer Center - Ohio Health | Columbus | Ohio | 44907 | — |
| University of Oklahoma Health Science Center | Oklahoma City | Oklahoma | 73104 | — |
| Oklahoma Cancer Specialists and Research Institute | Tulsa | Oklahoma | 74146 | — |
| Oncology Associates of Oregon, P.C. | Eugene | Oregon | 97401 | — |
| LMG Gynecologic Oncology | Portland | Oregon | 97210 | — |
| Northwest Cancer Specialists, P.C. | Portland | Oregon | 97225 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | — |
| UPMC Magee-Womens Hospital | Pittsburgh | Pennsylvania | 15213 | — |
| Abington Memorial Hospital | Willow Grove | Pennsylvania | 19090 | — |
| Avera Gynecologic Oncology | Sioux Falls | South Dakota | 57105 | — |
| Texas Oncology - Austin Central | Austin | Texas | 78731 | — |
| Texas Oncology - Bedford | Bedford | Texas | 76022 | — |
| Texas Oncology - Dallas Presbyterian Hospital | Dallas | Texas | 75231 | — |
| Texas Oncology - Fort Worth | Fort Worth | Texas | 76104 | — |
| Memorial Hermann | Houston | Texas | 77030 | — |
| University of Texas MD Anderson Cancer Center | Houston | Texas | 77030 | — |
| Texas Oncology - San Antonio Medical Center | San Antonio | Texas | 78240 | — |
| Texas Oncology - The Woodlands, Gynecologic Oncology | The Woodlands | Texas | 77380 | — |
| Huntsman Cancer Institute | Salt Lake City | Utah | 84112 | — |
| Virginia Oncology Associates | Norfolk | Virginia | 23502 | — |
| Froedtert and Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 174 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03522246, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 24, 2025 · Synced Oct 18, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03522246 live on ClinicalTrials.gov.