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Completed Phase 3 Interventional Results available

A Study to Assess if Mirikizumab is Effective and Safe Compared to Secukinumab and Placebo in Moderate to Severe Plaque Psoriasis (OASIS-2)

ClinicalTrials.gov ID: NCT03535194

Public ClinicalTrials.gov record NCT03535194. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 24, 2026, 8:46 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study Comparing the Efficacy and Safety of Mirikizumab to Secukinumab and Placebo in Patients With Moderate-to-Severe Plaque Psoriasis OASIS-2

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The reason for this study is to see how effective and safe mirikizumab is compared to secukinumab and placebo for moderate to severe plaque psoriasis.

Study identification

NCT ID
NCT03535194
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Eli Lilly and Company
Industry
Enrollment
1,484 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 26, 2018 (Actual)
Primary completion
Mar 5, 2020 (Actual)
Completion
Jun 3, 2020 (Actual)
Last update posted
Mar 30, 2021

2018 – 2020

United States locations

U.S. sites
42
U.S. states
22
U.S. cities
40
Facility City State ZIP Site status
University of Alabama at Birmingham Birmingham Alabama 35233 —
Bakersfield Dermatology and Skin Cancer Medical Group Bakersfield California 93309 —
David Stoll, M.D. Beverly Hills California 90212 —
California Dermatology and Clinical Research Institute Encinitas California 92024 —
Tien Q. Nguyen, MD inc. DBA First OC Dermatology Fountain Valley California 92708 —
Keck School of Medicine University of Southern California Los Angeles California 90033 —
Dermatology Clinical Trials Newport Beach California 92660 —
San Luis Dermatology & Laser Clinic, Inc San Luis Obispo California 93405 —
Clinical Science Institute Santa Monica California 90404 —
Park Avenue Dermatology Orange Park Florida 32073 —
Dermatologic Surgery Specialists, PC Macon Georgia 31217 —
Medaphase Inc Newnan Georgia 30263 —
Meridian Clinical Research Savannah Georgia 31406 —
Treasure Valley Dermatology Boise Idaho 83713 —
University Dermatology Darien Illinois 60561 —
Arlington Dermatology Rolling Meadows Illinois 60008 —
Dawes Fretzin Clinical Research Indianapolis Indiana 46250 —
The Indiana Clinical Trials Center, PC Plainfield Indiana 46168 —
The South Bend Clinic South Bend Indiana 46617 —
Dermatology Specialist Louisville Kentucky 40241 —
DelRicht Research Baton Rouge Louisiana 70809 —
Dermatology and Skin Cancer Specialists Rockville Maryland 20850 —
Lawrence J Green, M.D, LLC Rockville Maryland 20850 —
ORA, Inc Andover Massachusetts 01810 —
Central Dermatology PC St Louis Missouri 63117 —
Psoriasis Treatment Center of Central New Jersey East Windsor New Jersey 08520 —
Mount Sinai School of Medicine Dermatology Clinical Trials New York New York 10029 —
PMG Research of Cary, LLC Cary North Carolina 27511 —
University of North Carolina Dermatology and Skin Cancer Cen Chapel Hill North Carolina 27516 —
PMG Research of Wilmington, LLC Wilmington North Carolina 28401 —
Bexley Dermatology Research Bexley Ohio 43209 —
University Hospitals Cleveland Medical Center Cleveland Ohio 44106 —
Wright State Physicians Dermatology Fairborn Ohio 46435 —
Oregon Dermatology and Research Center Portland Oregon 97210 —
Oregon Health and Science University Portland Oregon 97239 —
Clinical Partners LLC Johnston Rhode Island 02919 —
Modern Research Associates PLLC Dallas Texas 75231 —
Austin Institute for Clinical Research, Inc. Pflugerville Texas 78660 —
Texas Dermatology and Laser Specialists San Antonio Texas 78218 —
Jordan Valley Dermatology Center West Jordan Utah 84088 —
Virginia Clinical Research Norfolk Virginia 23502 —
Dermatology Associates Seattle Washington 98101 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 136 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03535194, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 30, 2021 · Synced Oct 24, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT03535194 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →